DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rlip and Arhgap15

DIOPT Version :9

Sequence 1:	NP_650933.2	Gene:	Rlip / 42484	FlyBaseID:	FBgn0026056	Length:	625	Species:	Drosophila melanogaster
Sequence 2:	NP_722542.2	Gene:	Arhgap15 / 76117	MGIID:	1923367	Length:	481	Species:	Mus musculus

Alignment Length:	254	Identity:	60/254 - (23%)
Similarity:	108/254 - (42%)	Gaps:	28/254 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   138 KKKDKEEKRKE-----KDKKADKKDKKDKKS--KQLSQQQDDVSAAEEVLALGYPVFGVSVSLAT 195
            :|:.|.|.||.     ....:|..||...||  |:...::..:...:|...:...:||..:....
Mouse   229 RKEQKPEHRKSFMFRLHHSASDTSDKNRVKSRLKKFISRRPSLKTLQEKGLIKDQIFGSHLHTVC 293

  Fly   196 ERSRCHDGVDIPLVVRDCIDFLQDH-LKCEQIYKIEPIKTRLMHFKRLYNNRE----HDSAVDEL 255
            ||...    .:|..|:.||:.::.. |..:.||::......:...:.:.|..|    .||..:::
Mouse   294 EREHS----TVPWFVKQCIEAVEKRGLDVDGIYRVSGNLATIQKLRFIVNQEEKLNLDDSQWEDI 354

  Fly   256 NLPTACSLLKLFLRELPEPLLTTDLVARFEEVA----SHPKVTTQQAELQQLLEQLPKCNRTLLA 316
            ::.|..  ||:|.|||.|||.......||.|..    |:.|:.|    ::.|:::||..|...:.
Mouse   355 HVVTGA--LKMFFRELSEPLFPYSFFERFVEAIKKQDSNEKIET----MRSLVKRLPPPNHDTMK 413

  Fly   317 WVLLHFDAVIQQERHNKLNAQSLAMLLSPTLQMSHRLMVALLCHC--NNLFADVQLIKY 373
            .:..|...::.:...|.::.|||.::..|||..:......:..|.  .|..|:..|.:|
Mouse   414 ILFRHLTKIVAKASQNLMSTQSLGIVFGPTLLRAENESGNVAVHMVYQNQIAEFMLTEY 472

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rlip	NP_650933.2	RhoGap_RalBP1	187..368	CDD:239846	46/191 (24%)
Arhgap15	NP_722542.2	PH	88..196	CDD:278594
		PH_ARHGAP9-like	89..198	CDD:270053
		RhoGAP_ARHGAP27_15_12_9	285..471	CDD:239868	47/195 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910