Protein Alignment Rlip and Arhgap18

DIOPT Version :9

• Sequence 1: NP_650933.2
• Gene: Rlip / 42484
• FlyBaseID: FBgn0026056
• Length: 625
• Species: Drosophila melanogaster
• Sequence 2: NP_789807.1
• Gene: Arhgap18 / 73910
• MGIID: 1921160
• Length: 663
• Species: Mus musculus
• Alignment Length: 651
• Identity: 144/651 - (22%)
• Similarity: 253/651 - (38%)
• Gaps: 178/651 - (27%)

  Fly     6 PEEKEFPGLYASEAADAKSR---KSKEESDFSEDHDHSKKDLLIGRRKD----KKEKGKDRGYAA 63
            ||...|....:.::.|....   ...|....|.::....::.::.:..|    ::|..|:.|.:.
Mouse    55 PERPPFDRSSSQDSLDESMEAYWTELENIKRSNENRQEGQEAIVVKEPDEGELEEEWLKEAGLSN 119

  Fly    64 LEGES--SPEEEL------------------DTKSPSKSKKSKTFKFTS-----SKSKEKREKSR 103
            |.|||  .|:|.:                  :|.|.:..||:|......     ::.:|.:||..
Mouse   120 LFGESIDDPQESILFLSTLTRTQAAAVQKRVETVSQTLRKKNKQHHIRDVRDIFAQQREAQEKPP 184

  Fly   104 DKS--------EKDSKHAEEEPSVSHKVKEKERDKEKDRDEPKKK--------------DKEEKR 146
            |.|        |...:..:::|| |..|..||:......|.|..:              :::|..
Mouse   185 DDSDLRSVRTNENKGQGKDDQPS-SGAVDSKEQISRVPEDTPASETDINLEVSFAEQAVNQKEFS 248

  Fly   147 KEKDKKADKKDK-------KDK-------------KSKQLSQQQDDVSAAEEVLALGYP------ 185
            ||:.:|....|.       |||             ..|..|....:::|..:||.|.:.
Mouse   249 KERTQKISSNDSLPSFRLPKDKTGTTRIGDLAPQDMKKVCSLSLIELTALYDVLGLEFKQQKAVK 313

  Fly   186 -------VFGVSVSLATER-SRCHDGVDIPLVVRDCIDFLQD-HLKCEQIYKIEPIKTRLMHF-- 239
                   :||:.:::..|: .|...|..|||:.:..|..::: .|:.|.:.:|.....|:.:.
Mouse   314 IKTRDSGLFGIPLTILLEQDQRKVPGTRIPLIFQKLISRIEEGSLETEGLLRIPGAAMRIKNLCQ 378

  Fly   240 ---KRLYNN-------REHDSAVDELNLPTACSLLKLFLRELPEPLLTTDLVARFEEVASHPKVT 294
               .:.|..       ::||:|          |||||||||||:|||:.:.:..|:.|.:.|...
Mouse   379 ELEAKFYEGTFNWESVKQHDAA----------SLLKLFLRELPQPLLSMEYLKAFQAVQNLPTRK 433

  Fly   295 TQQAELQQLLEQLPKCNRTLLAWVLLHFDAVIQQERHNKLNAQSLAMLLSPTLQMSHRL------ 353
            .|...|..|:..||..||..|..:|.....||..:..||:.|.::||:::|.|.|.|.|
Mouse   434 EQLQALNLLVILLPDANRDTLKALLEFLQRVIDNKEKNKMTAGNVAMVMAPNLFMCHTLGLKSSE 498

  Fly   354 -----MVALLCHCNNLFADVQLIKYVPPLTSTSPKLPDTPEDIQTELRKQDSLLSQIHSEMNAGF 413
                 |.|...:..:|     ||:| ..:..|.||.      |..::|||:
Mouse   499 QREFEMAAGTANVMHL-----LIRY-QKILWTIPKF------IVIQVRKQN-------------- 537

  Fly   414 ITKKREEQLWEVQRIITQLKRKL---RTFEKKQEKTAEEVDNSSSAPPAV-------------AS 462
            |..:::|     ::.:.:|.:|:   |...:||:|||    |.:..|..|             |.
Mouse   538 IENQKKE-----RKAMKKLLKKMAYDREKHEKQDKTA----NGADVPQGVIRVQAPHLSKVSMAI 593

  Fly   463 EDTTDSKPAGTPA--VSTNNSISQEEPKTDTLTPKDAPN--DFTIDPSTGFILLPKSNPHRENLL 523
            :.|.:.|.:...|  :|..:.::|...|.:....:...|  :..:|..|....|.:.||:.|.::
Mouse   594 QLTEELKASDVLARFLSQESGVAQTLKKGEVFLYEIGGNIGERCLDDDTHMKDLYQLNPNAEWVI 658

  Fly   524 R 524
            :
Mouse   659 K 659

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rlip	NP_650933.2	RhoGap_RalBP1	187..368	CDD:239846	58/205 (28%)
Arhgap18	NP_789807.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	14..73		4/17 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	85..106		2/20 (10%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	173..228		14/55 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	245..277		8/31 (26%)
		RhoGAP_ARHGAP18	321..534	CDD:239856	65/234 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1372
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000