Protein Alignment Rlip and Arhgap26

DIOPT Version :9

• Sequence 1: NP_650933.2
• Gene: Rlip / 42484
• FlyBaseID: FBgn0026056
• Length: 625
• Species: Drosophila melanogaster
• Sequence 2: XP_036017177.1
• Gene: Arhgap26 / 71302
• MGIID: 1918552
• Length: 823
• Species: Mus musculus
• Alignment Length: 641
• Identity: 129/641 - (20%)
• Similarity: 231/641 - (36%)
• Gaps: 128/641 - (19%)

  Fly    32 DFSEDHDHSKKDLLIGRRKDKKEKGKDRGYAALEGESSPEEELDTKSPSKSKKSKTFKFTSSKS- 95
            :.::|....|..|.|..:..:..         .||..|..|.|..|......:.||....:.:.
Mouse   225 ELAKDFGDFKTQLTISIQNTRNR---------FEGTRSEVESLMKKMKENPLEHKTISPYTMEGY 280

  Fly    96 ---KEKRE------KSRDKSEKDSKHAEEEPSVSHKVKEKERDKEKDRDEP--------KKKDKE 143
               :|||.      |.....::|||.....|.      :::...:...||.        :|.|..
Mouse   281 LYVQEKRHFGTSWVKHYCTYQRDSKQITMVPF------DQKSGGKGGEDESVTLKSCTRRKTDSI 339

  Fly   144 EKRKEKDKKADKKDKKDKKSKQLSQQQD-----DVSAAEEVLALGYPVFGVSVSLATERSRCHDG 203
            |||...|.:|  .|:....:.|...::|     :.....|      ||:..:....:|.:...|.
Mouse   340 EKRFCFDVEA--VDRPGVITMQALSEEDRRLWMEAMDGRE------PVYNSNRDSQSEGTAQLDS 396

  Fly   204 VDIPLVVRDCIDFLQDHLKCEQ-IYKIEPIKTRLMHFKRLYNNREHDSAVD-----ELNLPTACS 262
            :... ::|.||..::.....|| :|:|..:.:|:.....:..:.:..|..:     |..:.|..|
Mouse   397 IGFS-IIRKCIHAVETRGINEQGLYRIVGVNSRVQKLLSVLMDPKAASETETDICAEWEIKTVTS 460

  Fly   263 LLKLFLRELPEPLLTTDLVARFEEVASHPKVTTQQAELQQLLEQLPKCNRTLLAWVLLHFDAVIQ 327
            .||.:||.||.||:.......|.:.|......|:.:|:..|:.:||:.||.:|..::.|...|..
Mouse   461 ALKTYLRMLPGPLMMYQFQRSFIKAAKLENQETRVSEIHSLVHRLPEKNRQMLQLLMNHLANVAN 525

  Fly   328 QERHNKLNAQSLAMLLSPTLQMSHRLMVALLCHC--NNLFADVQLIKYVPPLTSTSPKLPDTPED 390
            ..:.|.:...:|.::..|||.......||.:...  .|:..:: ||:....:.:|.|.:|.|...
Mouse   526 NHKQNLMTVANLGVVFGPTLLRPQEETVAAIMDIKFQNIVIEI-LIENHEKIFNTVPDVPLTNAQ 589

  Fly   391 IQTELRK-QDSL--------LSQIHSEMNAGFITKKREEQLWEVQRIITQLKRKLRTFEKKQEKT 446
            :....:| .||.        |:..|:..:    |:|:|::    ..||..      :.|......
Mouse   590 LHLSRKKSSDSKPPSCSKRPLTLFHAVPS----TEKQEQR----NSIINS------SLESVSSSA 640

  Fly   447 AEEVDNSSSAPPAVASEDTT-----DSKPAGTPA-VSTNNSISQ-----EEPKTDTLTPKDAPND 500
            ...:::|||..|.:.|.|:.     .|:|:..|. .|..:.:|.     ..|.:...|...:.:.
Mouse   641 NSILNSSSSLQPNLNSSDSNLDVVKPSRPSSLPPNPSPTSPLSPSWPMFSAPSSPMPTSSTSSDS 705

  Fly   501 FTIDPSTGFI---------------------LLPKSNPHRENLLRLQIEYDELMEWQNELKARIV 544
            ..|....||:                     ||....|...||..|....:|.:...:....|
Mouse   706 SPIRSVAGFVWFSVAAVVLSLAWSSLHAVFSLLVNFVPCHPNLHLLFDRPEEAVREDSSTPFR-- 768

  Fly   545 AERNEVYRLKQLYEQQSINSQMASLASGSQAPPESDYERIIEHYTRENALLEHKKN 600
                   :.|.||..|:.:....|..:|:.      ::.:  |.::|...||...|
Mouse   769 -------KAKALYACQAEHDSELSFTAGTV------FDNV--HPSQEPGWLEGTLN 809

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rlip	NP_650933.2	RhoGap_RalBP1	187..368	CDD:239846	42/188 (22%)
Arhgap26	XP_036017177.1	BAR	61..234	CDD:416402	1/8 (13%)
		BAR-PH_GRAF_family	276..380	CDD:269953	22/117 (19%)
		RhoGAP_Graf	373..572	CDD:239839	47/206 (23%)
		SH3_GRAF	768..823	CDD:212997	12/59 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910