Protein Alignment Rlip and Arhgap42

DIOPT Version :9

• Sequence 1: NP_650933.2
• Gene: Rlip / 42484
• FlyBaseID: FBgn0026056
• Length: 625
• Species: Drosophila melanogaster
• Sequence 2: XP_576354.3
• Gene: Arhgap42 / 500943
• RGDID: 1564081
• Length: 875
• Species: Rattus norvegicus
• Alignment Length: 680
• Identity: 126/680 - (18%)
• Similarity: 229/680 - (33%)
• Gaps: 180/680 - (26%)

  Fly    46 IGRRKDKK---EKGKDRGYAALE-----GESSPEEELDTKSPSKSKKSKTFKFTS----SKSKEK 98
            ||..||.|   :|..::.|:.|:     .....|..|........::.:.|...|    .|.:|.
  Rat   124 IGAAKDGKKKFDKESEKYYSILDKHLNLSAKKKESHLQEADSQIGREHQNFYEASLEYVFKIQEV 188

  Fly    99 REKSR-------------------DKSEKDSKHAEEEPSVSHKVKEKERDKEKDRDEPKKKDKEE 144
            :||.:                   :..|...:.|..:..:...::....:.|..|.|.::..:..
  Rat   189 QEKKKFEFVEPLLSFLQGLFTFYHEGYELAQEFAPYKQQLQFNLQNTRNNFESTRQEVERLMQRM 253

  Fly   145 KRKEKDKKADK----------KDKK-------------DKKSKQLSQQQDDVSAAEEV--LALGY 184
            |...:|.:...          ::|:             ||.||..:....||.|:.::  |..|.
  Rat   254 KAANQDYRPPSQWTMEGYLYVQEKRPLGFTWTKHYCTYDKGSKMFTMSVSDVKASGKMNGLVTGS 318

  Fly   185 P-VFGVSVSL-----ATERSRCHDGVDIPLVVRDCIDFLQDH----------------------- 220
            | :|.:...:     :.::..|   .||.:|.|..|..||..
  Rat   319 PEMFKLKSCIRRKTDSIDKRFC---FDIEVVERHGIITLQAFSEANRKLWLEAMDGKEPIYTLPA 380

  Fly   221 --LKCEQIYK-----------IEPIKTRLMHFKRLYNNREHDSAVDEL----------------- 255
              .|.|::|.           |:.::||.::...||.....:|.|.:|
  Rat   381 IISKKEEMYLNEAGFNFVRKCIQAVETRGINILGLYRIGGVNSKVQKLMNTTFSPKSPPDMDIDI 445

  Fly   256 ---NLPTACSLLKLFLRELPEPLLTTDLVARFEEVASHPKVTTQQAELQQLLEQLPKCNRTLLAW 317
               :..|..|.||.:||.|.|||:|..|...|...........:...:..|:.:||:.||.:|..
  Rat   446 ELWDNKTITSGLKNYLRCLAEPLMTYKLHKDFIIAVKSDDQNYRVEAVHALVHKLPEKNREMLDI 510

  Fly   318 VLLHFDAVIQQERHNKLNAQSLAMLLSPTLQMSHRLMVALLCHC--NNLFADVQLIKYVPPL--T 378
            ::.|...|....:.|.:...:|.::..|||..:....||.:.:.  .|:..:: ||::...:  |
  Rat   511 LIKHLLKVSLHSQQNLMTISNLGVIFGPTLMRAQEETVAAMMNIKFQNIVVEI-LIEHYEKIFHT 574

  Fly   379 STSPKLPDTPEDIQTELRKQDSLLSQIHSEMNAGFITKKREEQLWEVQRIITQLKRKLRTFEKKQ 443
            :..|.:|......::..|:..::.....|....|..|....|
  Rat   575 APDPNIPLPQPQSRSGSRRTRAICLSTGSRKPRGRYTPCLAE----------------------- 616

  Fly   444 EKTAEEVDNSSSAPPAVASEDTTDSKPAGT-PAVSTNNSISQEEPKTDTLTPKD---------AP 498
                .:.|:.||:|         ||.|.|: .::|:::|......|:.:..|::         ||
  Rat   617 ----PDSDSYSSSP---------DSTPMGSIESLSSHSSEQNSTTKSTSCQPREKSGGIPWIAAP 668

  Fly   499 NDFTIDPSTGFILLPKSNPHRENLLRLQIEYD----ELMEWQNELKARIVAERNEVYRLKQLYEQ 559
            :......|.|.......:..||:..:..:|.|    ..:....::...|...:...|.|..|..
  Rat   669 SSSNGQKSLGLWTTSPESSSREDATKTDVESDCQSVASVTSPGDVSPPIDLVKKGPYGLSGLKR- 732

  Fly   560 QSINSQMASLASGSQAPPESDYERIIEHYT 589
               :|..:||.|.|.|.....|...|:..|
  Rat   733 ---SSASSSLRSISAAEGNKSYSGSIQSLT 759

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rlip	NP_650933.2	RhoGap_RalBP1	187..368	CDD:239846	49/243 (20%)
Arhgap42	XP_576354.3	BAR_GAP10-like	19..225	CDD:153318	18/100 (18%)
		BAR-PH_GRAF_family	267..376	CDD:269953	20/111 (18%)
		PH	267..369	CDD:278594	20/104 (19%)
		RhoGAP	369..567	CDD:295372	42/198 (21%)
		SH3_GRAF3	821..875	CDD:212999

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910