Protein Alignment Rlip and ralbp1

DIOPT Version :9

• Sequence 1: NP_650933.2
• Gene: Rlip / 42484
• FlyBaseID: FBgn0026056
• Length: 625
• Species: Drosophila melanogaster
• Sequence 2: NP_996963.1
• Gene: ralbp1 / 404612
• ZFINID: ZDB-GENE-040426-2098
• Length: 665
• Species: Danio rerio
• Alignment Length: 655
• Identity: 214/655 - (32%)
• Similarity: 334/655 - (50%)
• Gaps: 130/655 - (19%)

  Fly     5 SPEE---KEFPGLYAS------------EAADAKSRKSKEESDFSEDHDHSKKDLLIGRRKDKKE 54
            |.||   .:|||||.:            |..||.|...||         |:||     :.|.||:
Zfish    29 SSEEISPTKFPGLYRTGDPSPPHDGHHHEPPDAASDDEKE---------HNKK-----KNKFKKK 79

  Fly    55 KGKDRGYAALEGESSPEEELDTKSPSKSKKSKTFKFTSSKSKEKREKSRDKSEKDSKHAEEEPSV 119
            :.:..||||.:.:||.:   |.:||||.|:||..                       |..::||.
Zfish    80 EKRTEGYAAFQEDSSAD---DAESPSKMKRSKGI-----------------------HVFKKPSF 118

  Fly   120 SHKVKEKERDKEKDRDEPKKKDKEEKRKEKDKK----AD--KKDKKDKKSKQLSQQQDDVSAAEE 178
            |.|       ||||....:|..||||.|:|..|    ||  |:.|:.||.|:.|.:.:.|  ..|
Zfish   119 SKK-------KEKDFKVKEKGPKEEKAKDKKSKDLTAADVVKQWKEKKKKKKPSTEPEPV--ITE 174

  Fly   179 VLALGYPVFGVSVSLATERSRCHDGVDIPLVVRDCIDFLQDH-LKCEQIYKIEPIKTRLMHFKRL 242
            |.....|:||.|:..|..|:..:||:.:|.:.|:|:|:::.: :|||.||::..:|:::...|..
Zfish   175 VTVTFRPIFGASLVEAVRRTALYDGIQLPAIFRECVDYIESYGMKCEGIYRVSGMKSKVDELKAA 239

  Fly   243 YNNREHDSAVDELNLPTACSLLKLFLRELPEPLLTTDLVARFEEVASHPKVTTQQAELQQLLEQL 307
            | :||....::|.:..|..||||.:|||||:.||..:|..||||....|....:..|.|:||.::
Zfish   240 Y-DREECPCLEEYDPHTVASLLKQYLRELPDNLLGKELSLRFEEACGRPSEAEKLQEFQRLLTEV 303

  Fly   308 PKCNRTLLAWVLLHFDAVIQQERHNKLNAQSLAMLLSPTLQMSHRLMVALLCHCNNLFADVQLIK 372
            |..:|.||||::.|.|.||.:|...|:|.|:::::|:||:|:|:|::.....|...:|.||.|..
Zfish   304 PAGSRLLLAWLITHMDHVIAREADTKMNIQNISIVLNPTIQISNRVLYVFFTHVREMFGDVFLKP 368

  Fly   373 YVPPL----TSTSPKLPDTPEDIQTELRKQDSLLSQIHSEMNAGFITKKREEQLWEVQRIITQLK 433
            .|.||    .:|.|.||||.|.|:.|:|:|:.||:::|.::.||.....:||:|||||||:|.||
Zfish   369 VVHPLRWSNMATMPTLPDTQESIKEEIRRQEFLLNRLHRDLQAGVKDLSKEERLWEVQRIVTALK 433

  Fly   434 RKLRTFEKKQE---KTAEEVDNSSSAPPAVASEDTTDSKPAGTPAVSTNNSISQEEPKTDTLTPK 495
            ||||. .|:||   |.|:|:  :|.:...|:.|:.|:               ::||
Zfish   434 RKLRE-AKRQECETKIAQEI--ASLSKEDVSKEEMTE---------------NEEE--------- 471

  Fly   496 DAPNDFTIDPSTGFILLPKSNPHRENLLRLQIEYDELMEWQNELKARIVAERNEVYRLK------ 554
                  .|:     :||.:.|       .:..|.:||:..:..|:.:|..|:.|:.||:
Zfish   472 ------VIN-----LLLAQEN-------EILTEQEELISLEQVLRRQIATEKEEIERLRAEIADI 518

  Fly   555 QLYEQQSINSQMASLASGSQAPPESDYERIIEHYTRENALLEHKKNMLGMELKEERRACIALQVE 619
            |..:|....::..|..|.|::..|.:.:.|:|...::|..||:|...|...:.||:.|.:.|:|:
Zfish   519 QSRQQGRSETEEYSSDSESESEDEEELQMILEDLQKQNEELENKNTHLNQAIHEEQEAILELRVQ 583

  Fly   620 LRLQQ 624
            |||.|
Zfish   584 LRLLQ 588

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rlip	NP_650933.2	RhoGap_RalBP1	187..368	CDD:239846	66/181 (36%)
ralbp1	NP_996963.1	RhoGap_RalBP1	183..364	CDD:239846	66/181 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170580371
Domainoid	1	1.000	116	1.000	Domainoid score	I5943
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	286	1.000	Inparanoid score	I2830
OMA	1	1.010	-	-		QHG49463
OrthoDB	1	1.010	-	-		D514124at2759
OrthoFinder	1	1.000	-	-		FOG0005056
OrthoInspector	1	1.000	-	-		oto39474
orthoMCL	1	0.900	-	-		OOG6_107500
Panther	1	1.100	-	-	LDO	PTHR12783
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	11	10.910