DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Rlip and Bcr

DIOPT Version :9

Sequence 1:NP_650933.2 Gene:Rlip / 42484 FlyBaseID:FBgn0026056 Length:625 Species:Drosophila melanogaster
Sequence 2:XP_038955099.1 Gene:Bcr / 309696 RGDID:1307993 Length:1270 Species:Rattus norvegicus


Alignment Length:470 Identity:103/470 - (21%)
Similarity:172/470 - (36%) Gaps:143/470 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MDFDSPEEKE-FPG--LYASEAADA-KSRKSKEESDFSEDHDHSKKDLLIGRRKDKKEKGKDRGY 61
            :.|...:|.| .|.  |...|..|| |.:.|:.:||...:           :|.:|..|..:|..
  Rat   761 LSFQMVDELEALPNIPLVPDEELDALKIKISQIKSDIQRE-----------KRANKGSKVMERLR 814

  Fly    62 AALEGESSPEEELDTKSPS-----KSKKSKTFKFTSSKSKEK---REKSRDKSEK---------- 108
            ..|   |..|..|...|||     .|:..|::.|..|...|:   ||..|::.:|          
  Rat   815 KKL---SEQESLLLLMSPSMAFRVHSRNGKSYTFLISSDYERAEWRESIREQQKKCFKSFSLTSV 876

  Fly   109 ---------------------DSKHAEEEP-----------------------------SVSHKV 123
                                 .:|..:|.|                             |..:.|
  Rat   877 ELQMLTNSCVKLQTVHHIPLTINKEDDESPGLYGFLHAIVHSATGFKQSSNLYCTLEVDSFGYFV 941

  Fly   124 KEKERDKEKDRDEP----------------------KKKDKEEKRKEKDKKADKKDKKDKKSKQL 166
            .:.:....:|..||                      |..:|.:..||..:.|||  ...|...||
  Rat   942 NKAKTRVYRDTTEPNWNEEFEIELEGSQTLRILCYEKCYNKMKMAKEDGESADK--LMGKGQVQL 1004

  Fly   167 SQQ--QD--------DVSAAEEVLALGYP----------------VFGVSVSLATERSRCHDGVD 205
            ..|  ||        |::..|..|::.:.                ||||.:::.|:|.|.    .
  Rat  1005 DPQTLQDRDWQRTVIDMNGIEVKLSVKFTSREFSLKRMPSRKQTGVFGVKIAVVTKRERS----K 1065

  Fly   206 IPLVVRDCIDFLQDH-LKCEQIYKIEPIKTRLMHFKRLY--NNREHDSAVDELNLPTACSLLKLF 267
            :|.:||.|::.::.. ::...||::..:.|.:...|..:  ||::....:.|:::......|||:
  Rat  1066 VPYIVRQCVEEIERRGMEEVGIYRVSGVATDIQALKAAFDVNNKDVSVMMSEMDVNAIAGTLKLY 1130

  Fly   268 LRELPEPLLTTDLVARFEEVASHPKVTTQQAELQQLLEQLPKCNRTLLAWVLLHFDAVIQQERHN 332
            .|||||||.|.:....|.|..:......:::.:..||..||:.|.....::|.|...|.::|..|
  Rat  1131 FRELPEPLFTDEFYPNFAEGIALSDPVAKESCMLNLLLSLPEANLLTFLFLLDHLKRVAEKETVN 1195

  Fly   333 KLNAQSLAMLLSPTL 347
            |::..:||.:..|||
  Rat  1196 KMSLHNLATVFGPTL 1210

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
RlipNP_650933.2 RhoGap_RalBP1 187..368 CDD:239846 46/164 (28%)
BcrXP_038955099.1 Bcr-Abl_Oligo 3..75 CDD:401106
RhoGEF 501..688 CDD:395496
PH-like 683..876 CDD:418428 32/128 (25%)
C2_ABR 912..1032 CDD:176068 21/121 (17%)
RhoGAP_Bcr 1051..1251 CDD:239852 46/164 (28%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
21.910

Return to query results.
Submit another query.