Protein Alignment Rlip and Arhgap18

DIOPT Version :9

• Sequence 1: NP_650933.2
• Gene: Rlip / 42484
• FlyBaseID: FBgn0026056
• Length: 625
• Species: Drosophila melanogaster
• Sequence 2: NP_001164046.1
• Gene: Arhgap18 / 293947
• RGDID: 1305053
• Length: 665
• Species: Rattus norvegicus
• Alignment Length: 663
• Identity: 147/663 - (22%)
• Similarity: 252/663 - (38%)
• Gaps: 191/663 - (28%)

  Fly     5 SPEE----KEFPGLYASEAADAKSRKSK-------EESDFSEDHDHSKKDLLIGRRKD----KKE 54
            :||.    .|.|....|.:.|:....|.       |....|.::....::.::.:..|    ::|
  Rat    47 NPESSTKLSERPPFDRSSSQDSLDEVSMEAYWTELENIKRSTENCQEGQEAIVVKEPDEGELEEE 111

  Fly    55 KGKDRGYAALEGESSPEEE--------------------LDTKSPSKSKKSKTFKFTS-----SK 94
            ..|:.|.:.|.|||:.:.:                    ::|.|.:..||||.:....     ::
  Rat   112 WLKEAGLSNLFGESADDSQESIVFLSTLTRTQAAAVQKRVETVSQTLRKKSKQYHIPDVRDIFAQ 176

  Fly    95 SKEKREKSRDKS--------EKDSKHAEEEPSVSHKVKEKERDKEKDRDEP-------------- 137
            .:|.:|||.|.|        |.:.:..:::|| |..|..||.......|.|
  Rat   177 QREAQEKSPDDSDLRSVRTNENEDQGKDDQPS-SGAVDNKEPIPRVPEDIPASETDINLEVSFAE 240

  Fly   138 -----KKKDKEEKRKEKDKKAD------KKDK-----------KDKK-----------------S 163
                 |:..||..:|.:...|.      .|||           :|.|                 .
  Rat   241 QAVNQKELSKERMQKTRGNDASLPSFRLPKDKTGTTRIGDLAPQDMKKVCYLSLIELTALYDVLG 305

  Fly   164 KQLSQQQDDVSAAEEVLALGYPVFGVSVSLATER-SRCHDGVDIPLVVRDCIDFLQD-HLKCEQI 226
            .:|.||:     |.::......:||:.:::..|: .|...|..|||:.:..|..::: .|:.|.:
  Rat   306 VELKQQK-----AVKIKTRDSGLFGIPLTILLEQDQRKVPGTRIPLIFQKLISCIEEGSLETEGL 365

  Fly   227 YKIEPIKTRLMHF-----KRLYNN-------REHDSAVDELNLPTACSLLKLFLRELPEPLLTTD 279
            .:|.....|:.:.     .:.|..       ::||:|          |||||||||||:|||:|:
  Rat   366 LRIPGAAMRVKNLCQELEAKFYEGTFNWESVKQHDAA----------SLLKLFLRELPQPLLSTE 420

  Fly   280 LVARFEEVASHPKVTTQQAELQQLLEQLPKCNRTLLAWVLLHFDAVIQQERHNKLNAQSLAMLLS 344
            .:..|:.|.:.|....|...|..|:..||..||..|..:|.....||..:..||:.|.::||:::
  Rat   421 YLKAFQAVQNLPTKKEQLQALNLLVILLPDANRDTLKALLEFLQRVIDNKEKNKMTAVNVAMVMA 485

  Fly   345 PTLQMSHRL-----------MVALLCHCNNLFADVQLIKYVPPLTSTSPKLPDTPEDIQTELRKQ 398
            |.|.|.|.|           |.|...:..:|     ||:| ..|..|.||.      |..::||.
  Rat   486 PNLFMCHALGLKSSEHREFEMAAGTANTMHL-----LIRY-QKLLWTIPKF------IVNQVRKH 538

  Fly   399 DSLLSQIHSEMNAGFITKKREEQLWEVQRIITQLKRKLRTFEKKQEKTAEEVDNSSSAPPAV--- 460
            ::    .|         :|:|      :|.:.:|.:|:....:|.|| .:...|.:..|..|
  Rat   539 NT----AH---------QKKE------RRAMKKLLKKMAYDREKHEK-QDRAANGADVPQGVIRV 583

  Fly   461 ----------ASEDTTDSKPAGTPA--VSTNNSISQEEPKTDTLTPKDAPN--DFTIDPSTGFIL 511
                      |.:.|.:.|.:...|  :|..:.::|...|.:....:...|  :..:|..|....
  Rat   584 QAPHLSKVSMAIQLTEELKASDVLARFLSQESGVAQTLKKGEVFLYEIGGNIGERCLDDDTYMKD 648

  Fly   512 LPKSNPHRENLLR 524
            |...||:.|.:::
  Rat   649 LYHLNPNAEWVIK 661

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rlip	NP_650933.2	RhoGap_RalBP1	187..368	CDD:239846	59/205 (29%)
Arhgap18	NP_001164046.1	RhoGAP_ARHGAP18	323..536	CDD:239856	67/234 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1372
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.000