Protein Alignment Rlip and ralbp1

DIOPT Version :9

• Sequence 1: NP_650933.2
• Gene: Rlip / 42484
• FlyBaseID: FBgn0026056
• Length: 625
• Species: Drosophila melanogaster
• Sequence 2: XP_017950523.1
• Gene: ralbp1 / 100379815
• XenbaseID: XB-GENE-1016073
• Length: 673
• Species: Xenopus tropicalis
• Alignment Length: 668
• Identity: 215/668 - (32%)
• Similarity: 341/668 - (51%)
• Gaps: 130/668 - (19%)

  Fly     5 SPEE---KEFPGLYASEAADAKSRKSKEESDF-SEDH-DHSKKDLLIGRRKDKKEKGKDRGYAAL 64
            |.||   .:|||||.:...........|..|. |||. ||.||     :.|.||::.:..||||.
 Frog    29 SSEEISPTKFPGLYRTGEPSPPHDIPYEPPDIVSEDEKDHGKK-----KGKFKKKEKRTEGYAAF 88

  Fly    65 EGESSPEEELDTKSPSKSKKSKTFKFTSSKSKEKREKSRDKSEKDSKHAEEEPSVSHKVKEKERD 129
            :.:||.:|   .:||||.|:||..                       |..::||.|   |:||:|
 Frog    89 QEDSSGDE---AESPSKMKRSKGI-----------------------HVFKKPSFS---KKKEKD 124

  Fly   130 ---KEKDRDEPKKKDKEEKRKEKDKKAD---KKDKKDKKSKQLSQQQDDVSAAEEVLALGYPVFG 188
               |||.:::..|:||.:::|.||..|.   |:.|:.||.|:.:.:.:.:......|.   |:||
 Frog   125 FKIKEKPKEDKHKEDKHKEKKSKDLTAADVVKQWKEKKKKKKPTPEPESLPVDIPRLR---PMFG 186

  Fly   189 VSVSLATERSRCHDGVDIPLVVRDCIDFLQDH-LKCEQIYKIEPIKTRLMHFKRLYNNREHDSAV 252
            :.:..|.||:..:||:.:|.|.|:|||:::.| :|||.||::..||:::...|..|:..|..: :
 Frog   187 IPLVEAAERTMMYDGIRLPAVFRECIDYIEQHGMKCEGIYRVSGIKSKVDELKAAYDRGESPN-L 250

  Fly   253 DELNLPTACSLLKLFLRELPEPLLTTDLVARFEEVASHPKVTTQQAELQQLLEQLPKCNRTLLAW 317
            ::....|..||||.:||||||.:||.||:.||||.........:..|.|:||::||:||..|.:|
 Frog   251 EDYEPYTVASLLKQYLRELPENVLTKDLMPRFEEACGKSTEGERLQECQRLLKELPECNFCLTSW 315

  Fly   318 VLLHFDAVIQQERHNKLNAQSLAMLLSPTLQMSHRLMVALLCHCNNLFADVQLIKYVPPL----T 378
            :::|.|.||::|...|:|.|:::::||||:|:|:|::.....|...||..:|:.:.:.||    .
 Frog   316 LIVHMDHVIEKELETKMNIQNISIVLSPTVQISNRVLYVFFTHVQELFGGIQIKRVIKPLRWSNM 380

  Fly   379 STSPKLPDTPEDIQTELRKQDSLLSQIHSEMNAGFITKKREEQLWEVQRIITQLKRKLRTFEKK- 442
            :|.|.||:|.|.|:.|:|:|:.||:.:|.|:.||.....:||:|||||||:|.||||||..:::
 Frog   381 ATMPTLPETQETIKEEIRRQEFLLNCLHRELQAGIKDLSKEERLWEVQRILTALKRKLREAKRQD 445

  Fly   443 -QEKTAEEVDNSSSAPPAVASEDTTDSKPAGTPAVSTNNSISQEEPKTDTLTPKDAPNDFTIDPS 506
             :.|.|:|:  :|.:...|:.|:.|:               ::||...
 Frog   446 CETKIAQEI--ASLSKEDVSKEEMTE---------------NEEEVLN----------------- 476

  Fly   507 TGFILLPKSNPHRENLLRLQIEYDELMEWQNELKARIVAERNEVYRLK-QLYEQQSINSQMA--- 567
               |||.:.|       .:..|.:||:..:..|:.:|..|:.|:.||: ::.|.||...|..
 Frog   477 ---ILLAQEN-------EILTEQEELVAMEQYLRRQIATEKEEIERLRAEISEIQSRQQQHGRSE 531

  Fly   568 ----SLASGSQAPPESDYERIIEHYTRENALLEH----------------------KKNMLGMEL 606
                |..|.|::..|.:.:.|:|...|:|..||.                      |.|.|...:
 Frog   532 TEEYSSESESESEDEDELQYILEDLQRQNEELEEHWDTSQDLCWVLRLTFCLFHQIKNNHLNQAI 596

  Fly   607 KEERRACIALQVELRLQQ 624
            .|||.|.|.|:|:|||.|
 Frog   597 HEEREAIIELRVQLRLLQ 614

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rlip	NP_650933.2	RhoGap_RalBP1	187..368	CDD:239846	71/181 (39%)
ralbp1	XP_017950523.1	RhoGap_RalBP1	185..366	CDD:239846	71/181 (39%)
		SMC_prok_B	<390..>571	CDD:274008	63/224 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	120	1.000	Domainoid score	I5692
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	287	1.000	Inparanoid score	I2772
OMA	1	1.010	-	-		QHG49463
OrthoDB	1	1.010	-	-		D514124at2759
OrthoFinder	1	1.000	-	-		FOG0005056
OrthoInspector	1	1.000	-	-		oto104418
Panther	1	1.100	-	-	LDO	PTHR12783
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4417
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	10.110