DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rlip and si:dkeyp-68b7.12

DIOPT Version :9

Sequence 1:	NP_650933.2	Gene:	Rlip / 42484	FlyBaseID:	FBgn0026056	Length:	625	Species:	Drosophila melanogaster
Sequence 2:	XP_021324056.1	Gene:	si:dkeyp-68b7.12 / 100151151	ZFINID:	ZDB-GENE-141212-333	Length:	1429	Species:	Danio rerio

Alignment Length:	329	Identity:	63/329 - (19%)
Similarity:	139/329 - (42%)	Gaps:	56/329 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   205 DIPLVVRDCIDFLQDHLKCEQIYKIEPIKTRLMHFKRLYNNREHDSAVDEL---NLPTACSLLKL 266
            |:|.|:|.|.:|::.|...:.||::..:.:.....:..:::........|:   ::....||.|.
Zfish    29 DVPQVLRSCSEFIEKHGIVDGIYRLSGVSSNTQKLRSEFDSEGSPDLYKEVYLQDIHCVSSLCKA 93

  Fly   267 FLRELPEPLLTTDLVARFEEVASHPKVTTQQAELQQLLEQLPKCNRTLLAWVLLHFDAVIQQERH 331
            :.||||.||||.:|..||.:..:......:..:::::|:.||..:...|.:::.|...:......
Zfish    94 YFRELPNPLLTYELYDRFADAVAVQLEDERLVKIREVLKDLPAPHYRTLEFLMRHLVKMSTFASE 158

  Fly   332 NKLNAQSLAMLLSPTLQMSHRL--------------------MVALLCHCNNLF----------- 365
            ..:::::||::.:|.|..|..:                    :..:|.|...||
Zfish   159 TNMHSRNLAIVWAPNLLRSKDIESTGFNGTAAFMEVRVQSIVVEFVLTHVPELFPETGVSMERRK 223

  Fly   366 ----------ADVQLIKYVPPLTSTSPKLPDTPEDIQTELRKQDSLLSQIHSEMNAGFITKKREE 420
                      .|....|.:|.::|.:.    :|.|....:|...:::.  .::...|.:..::.:
Zfish   224 SLPSPSILSSQDDHFFKSLPLISSGNL----SPGDGPLPMRPYHAIID--GTDKRKGSLKGRKWK 282

  Fly   421 QLWEVQRIITQLKRKLRTFEKKQEKT----AEEVDNSSSAPPAVASEDTTDSKPAGTPAVSTNNS 481
            .::.:...:...::|.:...|.:|||    |:.:|:.|:...|:  ||:...:.|..|.|.::.|
Zfish   283 SIFNLGARLHDPRKKNKYCPKDKEKTSLRPAKSMDSLSTGTTAL--EDSKPPQAALPPLVLSSAS 345

  Fly   482 ISQE 485
            .|.|
Zfish   346 GSSE 349

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rlip	NP_650933.2	RhoGap_RalBP1	187..368	CDD:239846	38/206 (18%)
si:dkeyp-68b7.12	XP_021324056.1	RhoGAP_CdGAP	13..207	CDD:239849	35/177 (20%)
si:dkeyp-68b7.12	XP_021324056.1	MDN1	<692..1250	CDD:331582
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D607176at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010