Protein Alignment Rlip and arhgap22

DIOPT Version :9

• Sequence 1: NP_650933.2
• Gene: Rlip / 42484
• FlyBaseID: FBgn0026056
• Length: 625
• Species: Drosophila melanogaster
• Sequence 2: XP_002940376.2
• Gene: arhgap22 / 100127847
• XenbaseID: XB-GENE-5807514
• Length: 544
• Species: Xenopus tropicalis
• Alignment Length: 543
• Identity: 121/543 - (22%)
• Similarity: 207/543 - (38%)
• Gaps: 165/543 - (30%)

  Fly   168 QQQDDVSAAEEVL--ALGYPVFGV----SVSLATERSRCHDGVDIPLVVRDCIDFLQDH-LKCEQ 225
            :.:|.|.|..:|:  ..|..|||.    :|||.|..:        ||||..|:||:::: |:.|.
 Frog    34 EMEDWVRAIHKVIWAPFGGAVFGQRLEDAVSLETRHA--------PLVVEQCVDFIRENGLQEEG 90

  Fly   226 IYKIEPIKTRLMHFKRLYNNREHDSAVDELNLPTACSLLKLFLRELPEPLLTTDLVARFEE---- 286
            ::::....|.:...:..:::....:.....::.|..|||||:|||||||::.   .:|:::
 Frog    91 LFRLPGQATLVKELQDTFDSGGKPTFDKSTDVHTVASLLKLYLRELPEPVIP---FSRYQDFLRC 152

  Fly   287 ---VASHPKVTTQQAELQQLLEQLPKCNRTLLAWVLLHFDAVIQQERHNKLNAQSLAMLLSPTL- 347
               ::......||  ||..|::.||..|..||.::....|.|......||:|.|:||.:.:|.:
 Frog   153 AHILSGDQGEGTQ--ELSILIKSLPPVNYNLLKYICSFLDEVQSYSDTNKMNVQNLATVFAPNIL 215

  Fly   348 ---------------QMSHRLMVALLCHCNN-LFADVQLIKYVPPLTSTSPKLPDTP--EDIQTE 394
                           .:.|  ::.:|.|.|: :|   |.:....|:..:..::.:|.  :|:.|
 Frog   216 RPKQQDPVALIEGASLIQH--LLTILIHENHWIF---QAVSADSPVGVSVQQIDNTQSIQDVDT- 274

  Fly   395 LRKQDSLLSQIHSEMNAGFITKKREEQLWEVQRIITQLK-------------------------- 433
               ..||...:|.          ..||.|...:|....|
 Frog   275 ---AKSLEPTLHG----------NHEQTWAKSQIFANWKASFMLSSSKPVFPSCDPSNLPPSVSW 326

  Fly   434 -----RKLRTFEKKQEKTAEEV---DNSSSAPPAVASEDTTD-----------SKPA-GTPAVST 478
                 ..||:.::|....|:.:   ||..|..|::.|.:.:.           |.|| |...||.
 Frog   327 LQDGFSSLRSHKEKDSVKAQRLSSYDNVPSCLPSLPSSNWSSFSNVSLNESLCSCPACGGSQVSQ 391

  Fly   479 NN------SISQEEPKTDTLTPKDAPNDFTIDPSTGFILLPKSNPHRENLLRLQIEYDELMEWQN 537
            .:      |:|:.|                    .|.:.||.|....|..:......|.|.....
 Frog   392 GSESGWHLSLSESE--------------------RGILPLPSSIERLELCVSSSGNSDTLTSDSG 436

  Fly   538 EL---KARIVAERNEVYRLKQLYEQQSINSQMASLASGSQAPPESDYERIIEHYTRENA-LLEHK 598
            |:   ..:||:|..|     ||.:||                  .:||..||...:..| :|.|.
 Frog   437 EVWNTYQKIVSELKE-----QLAKQQ------------------VEYENKIESLEKSRAEVLVHV 478

  Fly   599 KNMLGMELKEERRACIALQVELR 621
            :: |...|.:|:..|..|:::||
 Frog   479 RS-LQNTLDQEKNRCTLLEIKLR 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rlip	NP_650933.2	RhoGap_RalBP1	187..368	CDD:239846	54/209 (26%)
arhgap22	XP_002940376.2	PH-like	<16..52	CDD:388408	4/17 (24%)
		RhoGAP	53..247	CDD:383032	54/208 (26%)
		Myosin_tail_1	<446..>521	CDD:366712	21/79 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910