Protein Alignment Rlip and asap1

DIOPT Version :9

• Sequence 1: NP_650933.2
• Gene: Rlip / 42484
• FlyBaseID: FBgn0026056
• Length: 625
• Species: Drosophila melanogaster
• Sequence 2: XP_031759002.1
• Gene: asap1 / 100036721
• XenbaseID: XB-GENE-1013472
• Length: 1136
• Species: Xenopus tropicalis
• Alignment Length: 641
• Identity: 120/641 - (18%)
• Similarity: 224/641 - (34%)
• Gaps: 188/641 - (29%)

  Fly     9 KEFPGLYASEAADAKSRKSKEESDFSEDHDHSKKDLLIGRRKDKKE-KGKDRGYA--ALEGESSP 70
            |::....|::..:.|..:.:|:...:...|..|..|.:.:::.::: :.|..||:  .|:|
 Frog   262 KQYIEKLAADLYNIKQTQDEEKKQLTALRDLIKSSLQLDQKESRRDSQSKQAGYSMHQLQG---- 322

  Fly    71 EEELDTKSPSKSKKSKTFKFTSSKSKE-KREKSRDKSEKDSKHAEEEPSVSHKVKEKERDK---- 130
                 .|.....||....|.:....|. :|.|...|:        ...::||....:...|
 Frog   323 -----NKEYGSEKKGYLLKKSDGIRKVWQRRKCTVKN--------GILTISHATSNRPPTKLNLL 374

  Fly   131 ----EKDRDEPK--------------KKDKEE-------KRKEKDKKADKKDKKDKKSKQLSQQQ 170
                :.:.||.|              .:|::|       ....|:...:...:.|:.:.:.|.:.
 Frog   375 TCQVKPNADEKKCFDLISHNRTYHFQAEDEQEYIAWISVLTNSKEDALNMAFRGDQSTGESSLED 439

  Fly   171 ------DDV--SAAEEVLALGYPVFGVSVSLATERSRCHDGVDIP------LVVRDCIDF----- 216
                  |||  :...||.                   |..|...|      |.:..||:.
 Frog   440 LTKAIIDDVQKTPGNEVC-------------------CDCGSPDPTWLSTNLGILTCIECSGIHR 485

  Fly   217 -LQDHLKCEQIYKIEPIKT-RLMHFKRLYNNREHDSAVDELNLPTACSLLKLFLRELPEPLLTTD 279
             :..|:...|..:::.:.| .|:..|.:.||..:|.....|..|:|            :|..::|
 Frog   486 EMGVHISRIQSLELDKLGTSELLLAKNVGNNSFNDIMEGNLLSPSA------------KPSPSSD 538

  Fly   280 LVARFEEVAS-------HPKVTTQQAE-LQQLLEQLPKCNRTLLAWVLLHFDAV-IQQ---ERHN 332
            ::||.|.:.:       ..|:.:..|| |.:|||.:.  :|.|||.:.::.:.| |.:   |...
 Frog   539 MIARKEYITAKYVERRFSRKICSTGAEKLNELLEAVK--SRDLLALIQVYAEGVEIMEPLLESGQ 601

  Fly   333 KLNAQSLAMLLSPTLQMSHRLMVALLCHCNNLFADVQ----------------------LIKYVP 375
            :....:|...:......|..|:..|:.:|.||  |.|                      |::..|
 Frog   602 EPGETALHYAVRTADHTSLPLVDFLVQNCGNL--DKQTGKGNTALHYCCLYNKPECLKLLLRGKP 664

  Fly   376 PLTSTSPKLPDTPEDI-------QTELRKQDSLLSQIHSEMNAGFITKKREEQLWEVQRIITQLK 433
            .:.:.: .:.:|..|:       |.|.....:|..:::..::..:....|:|::.|..   ..|:
 Frog   665 TIDAVN-HIGETAFDVAKRQKAAQCEELVSQALAGKLNPHVHVEYDWNLRQEEMDESD---DDLE 725

  Fly   434 RKLRTFEKKQEKTAEEVDNSSSAPPAVASEDTTDSKPAGTP--------AVSTNN---SISQEEP 487
            .|....:|::....:...:|||..|    :|........||        ...||.   |.|.:.|
 Frog   726 DKPSPIKKERSPRPQSFCHSSSISP----QDKLSLPGFSTPRDKQRLSYGAFTNQIFMSTSTDSP 786

  Fly   488 KTDT-----LTPKDA------PNDFTIDPST----GFILLPKSNP------HRENL 522
            .:.|     |.|::|      |.. |:..||    |...|.|..|      |:..|
 Frog   787 TSPTADAPPLPPRNAGKVASGPTS-TLPLSTQSPSGSSTLSKKRPPPPPPGHKRTL 841

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rlip	NP_650933.2	RhoGap_RalBP1	187..368	CDD:239846	43/205 (21%)
asap1	XP_031759002.1	BAR_ASAP1	54..268	CDD:153325	1/5 (20%)
		PH_ASAP	319..425	CDD:270071	19/122 (16%)
		ArfGap_ASAP1	440..561	CDD:350073	28/151 (19%)
		Ank_2	585..660	CDD:403870	12/76 (16%)
		ANK repeat	604..637	CDD:293786	8/34 (24%)
		ANK repeat	639..670	CDD:293786	2/30 (7%)
		PHA03247	<735..1052	CDD:223021	26/112 (23%)
		SH3_ASAP1	1078..1134	CDD:212898

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910