Protein Alignment Rlip and acap3b

DIOPT Version :9

• Sequence 1: NP_650933.2
• Gene: Rlip / 42484
• FlyBaseID: FBgn0026056
• Length: 625
• Species: Drosophila melanogaster
• Sequence 2: NP_001076484.1
• Gene: acap3b / 100009646
• ZFINID: ZDB-GENE-070209-274
• Length: 846
• Species: Danio rerio
• Alignment Length: 558
• Identity: 108/558 - (19%)
• Similarity: 183/558 - (32%)
• Gaps: 159/558 - (28%)

  Fly   110 SKHAEEEPSVSHKVKEKERDKEK---------DRDEPKKKD------KEEKRKEKD-KKADKKDK 158
            |.|.::|..:|..:::.....::         |:.:...|.      ||:.||.|: ||...|.:
Zfish    65 SHHCKKEEMISECLEKCGESLQEIVNYHMILFDQAQRSVKQQLHSFVKEDVRKFKETKKQFDKVR 129

  Fly   159 KDKKSKQLSQQQDDVSAAEEVLALGYPVFGVSVSLATERSRCHDGVDIPLVVRDCIDFLQDHLKC 223
            :|.:..|:...|...:...||..      ..|..:.|.:...|..:|..|.    |:.||...|.
Zfish   130 EDMEIAQVKNAQAPRNKPHEVEE------ATSTLITTRKCFRHLALDYVLQ----INVLQAKKKF 184

  Fly   224 EQIYKIEPIKTRLMHFKRLYNNREHD--SAVDELNLPTACSLLKLFLRELPEPLLTTDLVARFEE 286
            |       |...::.|.:......|.  :.:||::     ..:|....||.:.::.:.:..|..|
Zfish   185 E-------ILDSMLSFMQAQYGLFHQGFNLLDEID-----PYMKKLAAELDQLVIDSAMEKREME 237

  Fly   287 VASHPKVTTQQAELQQ-------------------LLE--QLPKCNRTLLAWVLLHFDAVIQQER 330
               |...|.||..|.|                   ::|  ...:.:.....|....|.  ||
Zfish   238 ---HKHATIQQRTLMQDFAYDDSKVEFNVDAPNGVVMEGYLFKRASNAFKTWNRRWFS--IQ--- 294

  Fly   331 HNKLNAQSLAMLLSPTLQMSHRLMVALLCHCNNLFADVQLIKYVPPLTSTSPKLPDTPEDIQTE- 394
                |:|         |....||..||..    :..|::|....|            .|||:..
Zfish   295 ----NSQ---------LVYQKRLKDALTV----VVEDLRLCSVKP------------CEDIERRF 330

  Fly   395 ----LRKQDSLLSQIHSEMNAGFITKKREEQLWEVQRIITQLKRKL--RTFEKKQEKTA----EE 449
                :....|.:.|..||       |.|:..:..||..|....|::  ..:.::.::||    ..
Zfish   331 CFEVVSPTKSCMLQAESE-------KLRQAWIQAVQASIASAYREISENYYIERLDRTASPSTSS 388

  Fly   450 VDNSSSAPPAVASEDTTDSKPAGTPAVSTNNSISQEEPKTDTLTPKDAPNDFTIDPSTGFIL-LP 513
            :|::|.....|...|:...:....|.........|.:|:..::             :.|.:| :.
Zfish   389 IDSASEPRERVVRGDSILQRVQCLPGNEICCDCGQSDPRWASI-------------NLGILLCIE 440

  Fly   514 KSNPHRE--------NLLRLQIEYDELMEWQNELKARIVAERNEVYRLKQLYEQQSINSQMASLA 570
            .|..||.        ..|.|.....|||:...||...::   |::|  :...|:|.:.
Zfish   441 CSGIHRSLGVHCSKVRSLTLDTWEPELMKLMCELGNTVI---NQIY--EGACEEQGLK------- 493

  Fly   571 SGSQAPPESDYER---IIEHYTRENALLEHKKNMLGME 605
              ...|..|..|:   |...|.....|    |.|.|.|
Zfish   494 --KPGPNSSRQEKEAWIKAKYVERKFL----KKMCGSE 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rlip	NP_650933.2	RhoGap_RalBP1	187..368	CDD:239846	38/203 (19%)
acap3b	NP_001076484.1	BAR_ACAP3	16..215	CDD:153321	34/171 (20%)
		PH	269..363	CDD:278594	26/134 (19%)
		PH_ACAP	271..367	CDD:270070	27/136 (20%)
		ArfGap	403..520	CDD:279720	26/147 (18%)
		ANK repeat	666..697	CDD:293786
		ANK	668..787	CDD:238125
		Ank_2	671..759	CDD:289560
		ANK repeat	699..732	CDD:293786
		ANK repeat	734..759	CDD:293786

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910