DRSC/TRiP Functional Genomics Resources

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Protein Alignment Rlip and zgc:162872

DIOPT Version :9

Sequence 1:NP_650933.2 Gene:Rlip / 42484 FlyBaseID:FBgn0026056 Length:625 Species:Drosophila melanogaster
Sequence 2:XP_009290262.1 Gene:zgc:162872 / 100004931 ZFINID:ZDB-GENE-081022-1 Length:701 Species:Danio rerio


Alignment Length:520 Identity:98/520 - (18%)
Similarity:173/520 - (33%) Gaps:145/520 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly   204 VDIPLVVRDCIDFLQDHLKCEQIYKIEPIKTRLMHFKRLYNNREHDSAVDELNLPTACSLLKLFL 268
            :|....:||...|.|...|||.  .:..:::|:....:|..     ..||.....|:|:  :|||
Zfish     5 LDFEDCIRDSPAFRQSLDKCES--DMSELESRVEKVMKLCG-----QMVDAGQNYTSCN--QLFL 60

  Fly   269 RELPE-------PLLTTDLVARF----EEVASHPKV---TTQQAELQQLLEQL----PKCNRTLL 315
            ..|.|       ..:..:.:.:|    :|:.....:   .||:|..|||...|    |:...|..
Zfish    61 CALSEFTAYHKSDGVILNCLRQFNQGLQEMIQFQTMLFDQTQRAISQQLTNLLSQFVPQIRETRR 125

  Fly   316 AWVLLHFD---AVI---QQERHNKLNAQSLAMLLSPTLQMSHRLMVALLCHCNNLFADVQL---- 370
            .:|.:..|   ||:   |..||..::|:....||..|.:......:......||.....:|    
Zfish   126 EFVRIGDDLDSAVVKNAQVSRHKPVDAERATHLLLATRKCYQHFALDYCLQLNNFKVQQKLDILN 190

  Fly   371 --IKYVPPLTSTSPKLPDTPEDIQTELRKQDSLLSQIHSEMNA---------------------- 411
              ..|.....:...:..|...|::..::...|.|||:.::.:|                      
Zfish   191 SVFSYFHAQYTFFHQGFDLLRDLEPTMKTMASQLSQLSTDCSAKRKDLENTHLLVQQRDASGEAV 255

  Fly   412 ------------GFITK--KREEQLWEVQRIITQLKRKLRTFEKKQE-------------KTAEE 449
                        |::.|  :::.:.|:.....|:..:.:.....|::             |:.:.
Zfish   256 IVCNPSDGGTIQGYLFKRSRKKNKTWKRCWFSTENNQLIYLKSHKEQPVVLFDDLRLCAVKSLDV 320

  Fly   450 VDNS------SSAPPAVASEDTTDSKPAGTPAVSTNNSISQEEPKTDTLT-------PKDAPNDF 501
            :|..      |.....|...|:.:.|.|...||.....::..:..||..|       |...|:..
Zfish   321 IDRRFCFELLSVQKCCVLQADSEELKSAWMNAVQGCIDMAYRDQVTDQNTQVKESSAPVSIPDPP 385

  Fly   502 TIDPSTGFILLPKSNPH------------RENL-LRLQIEYD----------------ELMEWQN 537
            :..|:.|..|..:.|.|            ..|| :.:.||..                .|..|:.
Zfish   386 SHPPALGVALSGRGNQHCCDCGEAEPRWASVNLGITMCIECSGIHRSLGVHLSKVRSLTLDSWEP 450

  Fly   538 ELKARIVAERNEVYRLKQLYEQQSINSQMASLASGSQAP----PESDYER-IIEHYTRENALLEH 597
            |....:....|||  :..:||:::        |.|.|.|    |..|.|: |...|..:..:..|
Zfish   451 EQLKLLCVLGNEV--INGIYEREA--------ADGLQKPSAGSPRQDKEQWIRSKYVEKRFVARH 505

  Fly   598  597
            Zfish   506  505

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
RlipNP_650933.2 RhoGap_RalBP1 187..368 CDD:239846 43/187 (23%)
zgc:162872XP_009290262.1 BAR_ACAPs 18..217 CDD:153287 43/207 (21%)
PH 265..357 CDD:278594 14/91 (15%)
PH_ACAP 266..362 CDD:270070 14/95 (15%)
ArfGap 399..504 CDD:279720 23/114 (20%)
Ank_2 <508..583 CDD:289560
ANK 522..638 CDD:238125
ANK repeat 552..583 CDD:293786
Ank_2 557..649 CDD:289560
ANK repeat 585..616 CDD:293786
ANK repeat 618..649 CDD:293786
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.910

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