Protein Alignment Alp5 and PHO8

DIOPT Version :10

• Sequence 1: NP_650931.1
• Gene: Alp5 / 42482
• FlyBaseID: FBgn0038845
• Length: 522
• Species: Drosophila melanogaster
• Sequence 2: NP_010769.3
• Gene: PHO8 / 852092
• SGDID: S000002889
• Length: 566
• Species: Saccharomyces cerevisiae
• Alignment Length: 564
• Identity: 149/564 - (26%)
• Similarity: 225/564 - (39%)
• Gaps: 169/564 - (29%)

  Fly    52 RVVDGEDTNAYWRQQ----------------GVQFVQQKLA--------SEPNKRQAKNVILFLG 92
            |:|.|.|:::..:::                |:..|..:||        |..:|:  ||||.|:.
Yeast    12 RLVPGSDSSSRPKKRRISKRSKIIVSTVVCIGLLLVLVQLAFPSSFALRSASHKK--KNVIFFVT 74

  Fly    93 DGMGVTTTSAARNLLGGEEKSLSFENF-----PFTGLSKTYSVDKIVPDSACTATAYLCGVKGQE 152
            ||||..:.|.||: .......|..::.     .|.|.|:|.|.|.:|.|||..|||:.|.:|...
Yeast    75 DGMGPASLSMARS-FNQHVNDLPIDDILTLDEHFIGSSRTRSSDSLVTDSAAGATAFACALKSYN 138

  Fly   153 GTIGVNGQVPRTDCKVMLDESTHVDSIAKWAMEAGKWAGLVTTTRVTHASPSGVYAHIAERDWEN 217
            |.|||:..  ...|..:|:.          |..||...|||.|||:|.|:|:...:|:..| |:.
Yeast   139 GAIGVDPH--HRPCGTVLEA----------AKLAGYLTGLVVTTRITDATPASFSSHVDYR-WQE 190

  Fly   218 DAEVATDCGAGSGINDIAYQLARGEVGSKLKVIMGGGRKHFVD-----SSLESWGKRTDGLNLID 277
            |. :||            :||....:|..:.::|||||.||..     |.....|.|.||.:|||
Yeast   191 DL-IAT------------HQLGEYPLGRVVDLLMGGGRSHFYPQGEKASPYGHHGARKDGRDLID 242

  Fly   278 E------------------FKSASENNVYVTTAAELAAVDVTKTDRLLGLFNDDHLQYLMETTTE 324
            |                  .||..||   ||..             .||||.|:.:.:.:: ..|
Yeast   243 EAQSNGWQYVGDRKNFDSLLKSHGEN---VTLP-------------FLGLFADNDIPFEID-RDE 290

  Fly   325 SSQPTLEQMTRKAIEYM--SQNE----QGYFLFIEGGRIDQAHHINQARMALNETIEFSKAIAAA 383
            ...|:|::..:.|:..:  :.||    .|:||.:||.|||.|.|.|.....:.|.:.|.:|....
Yeast   291 KEYPSLKEQVKVALGALEKASNEDKDSNGFFLMVEGSRIDHAGHQNDPASQVREVLAFDEAFQYV 355

  Fly   384 QEL--TSEDDTLLVVTADH-------SHVFT-----YAGY-------SYRGSDVFGKTP--VNGH 425
            .|.  .|:.:|:||.|:||       |...|     |..|       ::.|..:..|..  |:.|
Yeast   356 LEFAENSDTETVLVSTSDHETGGLVTSRQVTASYPQYVWYPQVLANATHSGEFLKRKLVDFVHEH 420

  Fly   426 DGKPYMVLSYANGPSYENFYDAETMER---------KDPTTVVKGDHDDEFPSGVP---IDMDS- 477
            .|....:         |||...|.:|:         .|..|::   |.|:..:.:.   .||.|
Yeast   421 KGASSKI---------ENFIKHEILEKDLGIYDYTDSDLETLI---HLDDNANAIQDKLNDMVSF 473

  Fly   478 ----------HGGDDVPVYAL----GPWAHLFT---GVYEQSTI 504
                      |...||.:||.    ..|:::..   |.:|.:.:
Yeast   474 RAQIGWTTHGHSAVDVNIYAYANKKATWSYVLNNLQGNHENTEV 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Alp5	NP_650931.1	alkPPc	85..515	CDD:214515	139/507 (27%)
PHO8	NP_010769.3	Alk_phosphatase	66..527	CDD:395188	139/510 (27%)