Protein Alignment Alp5 and Alp1

DIOPT Version :9

• Sequence 1: NP_650931.1
• Gene: Alp5 / 42482
• FlyBaseID: FBgn0038845
• Length: 522
• Species: Drosophila melanogaster
• Sequence 2: NP_001262159.1
• Gene: Alp1 / 40372
• FlyBaseID: FBgn0283479
• Length: 530
• Species: Drosophila melanogaster
• Alignment Length: 482
• Identity: 225/482 - (46%)
• Similarity: 299/482 - (62%)
• Gaps: 25/482 - (5%)

  Fly    62 YWRQQGVQFVQQKLASEPNKRQAKNVILFLGDGMGVTTTSAARNLLG------GEEKSLSFENFP 120
            :|.....:.:..||::.||:.:|||||.||||||.|.|.:|.|...|      ||...|.||.|.
  Fly    42 FWFHDAQRTLYNKLSTPPNQYRAKNVIFFLGDGMSVPTVTAGRIFDGQLRGVVGERNRLEFEKFN 106

  Fly   121 FTGLSKTYSVDKIVPDSACTATAYLCGVKGQEGTIGVNGQVPRTDCKVMLDESTHVDSIAKWAME 185
            :.||||||.|:|.|.||||||:|||.|:|....||||...|...||:........:.|||.||::
  Fly   107 YVGLSKTYCVNKQVADSACTASAYLSGIKANYLTIGVTADVELNDCRGSRLPQNRLSSIAAWALK 171

  Fly   186 AGKWAGLVTTTRVTHASPSGVYAHIAERDWENDAEVATDCGAGSG-INDIAYQLARGEVGSKLKV 249
            ..|.||||||||||||||:|||||.:.||:|:|.:| |..|...| ..|||.||..|:||.:|:|
  Fly   172 GSKSAGLVTTTRVTHASPAGVYAHTSNRDFESDYDV-TKLGQNPGNCPDIAQQLIDGDVGKRLRV 235

  Fly   250 IMGGGRKHFVDSSLE----SWGKRTDGLNLIDEFKSASENNVYVT-TAAELAAVDVTKTDRLLGL 309
            :||||...|:.::..    :.|:|.|..|||:|::.....|..|. :..:|...|...||.||||
  Fly   236 VMGGGTIKFLPNTTNDVFGNKGQRLDNRNLIEEWQQTKPGNARVVFSRTDLLNNDAQNTDFLLGL 300

  Fly   310 FNDDHLQYLMETTTESSQPTLEQMTRKAIEYMSQNEQGYFLFIEGGRIDQAHHINQARMALNETI 374
            ||..||.|.|:.:.::  |||.:||..||..:|::..|||||:||||||.|||..:|:.||:||:
  Fly   301 FNASHLAYHMDDSIDT--PTLPEMTAAAINVLSRDPNGYFLFVEGGRIDHAHHETKAKKALDETV 363

  Fly   375 EFSKAIAAAQELTSEDDTLLVVTADHSHVFTYAGYSYRGSDVFG-KTPVNGHDGKPYMVLSYANG 438
            :||.|:..|::||:..|||:||:|||.|..|.:||....:.:.| .:.::..|..||..:|||||
  Fly   364 QFSDAVRKARQLTNPWDTLIVVSADHGHTVTISGYPDVNNSIVGLNSELSNVDQLPYTSISYANG 428

  Fly   439 PSYENFYDAE--TMERKDPTTVVKGDHDDEFPSGVPIDMDSHGGDDVPVYA-------LGPWAHL 494
            |:||.||.:.  .:||.|...:.....|..:|.|||:..::|||.||.|||       .|||:||
  Fly   429 PAYERFYKSTDGVVERVDLRNLDFSKPDAIYPHGVPMTEETHGGGDVAVYAHVVEYLLQGPWSHL 493

  Fly   495 FTGVYEQSTIPHMMAYASCLGDGHTMC 521
            |||||||||:||:|.:|||||.|.|.|
  Fly   494 FTGVYEQSTLPHLMGFASCLGPGITYC 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Alp5	NP_650931.1	Alk_phosphatase	84..514	CDD:278666	214/451 (47%)
Alp1	NP_001262159.1	alkPPc	65..514	CDD:214515	214/451 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466628
Domainoid	1	1.000	363	1.000	Domainoid score	I896
eggNOG	1	0.900	-	-		E1_COG1785
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	383	1.000	Inparanoid score	I2001
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D216917at33208
OrthoFinder	1	1.000	-	-		FOG0000192
OrthoInspector	1	1.000	-	-		mtm6481
orthoMCL	1	0.900	-	-		OOG6_100381
Panther	1	1.100	-	-	P	PTHR11596
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R959
SonicParanoid	1	1.000	-	-		X159
	12	11.830