Protein Alignment Grik and ATGLR1.2

DIOPT Version :10

• Sequence 1: NP_001262788.1
• Gene: Grik / 42476
• FlyBaseID: FBgn0038840
• Length: 907
• Species: Drosophila melanogaster
• Sequence 2: NP_199651.1
• Gene: ATGLR1.2 / 834895
• AraportID: AT5G48400
• Length: 867
• Species: Arabidopsis thaliana
• Alignment Length: 933
• Identity: 188/933 - (20%)
• Similarity: 340/933 - (36%)
• Gaps: 240/933 - (25%)

  Fly    15 LGFILTSLLLAFPGC----------RGERTNVGLVYENTDPDLEKIFHLAISKA--------NEE 61
            |.|:|. ||.....|          :..|..||||.:....: .||...::|.|        |:.
plant    12 LSFLLV-LLFFISNCFASSQNNDDDKRIRVRVGLVLDLGSVE-GKIVRSSVSMALSDFYDNHNDY 74

  Fly    62 NEDLQL-----HGVSVSIEPGNSFETSKKLCKMLRQNLVAVFGPTSNLAARHAMSICDAKELPFL 121
            ...|.|     ||     ||..:.::...|  :..:.:.|:.|         ..|:.:||.|..|
plant    75 KTRLSLLVRDSHG-----EPLLALDSVVDL--LQTEGVQAIIG---------GNSLLEAKLLAEL 123

  Fly   122 DTRWDFGAQLPTINLHPHPATLGVA------------------LRDMVVALGWESFTIIYES-GE 167
            ..:    |::|.|:|: .|.:|.::                  :...:....|.|..::.|. .:
plant   124 GEK----ARVPVISLN-SPMSLSLSKYTHLIQATHNSASEVKGITAFLHGFDWNSVALVLEDHDD 183

  Fly   168 YLPTVRELLQMYGTAGPTVTVRRYELDLNGNYRNVLRRIRNADDFS---FVVVGSMATLPEFFKQ 229
            :..::..::..:......|. .:....:..:..:::.|:|...|..   |||..|.......|..
plant   184 WRESMHFMVDHFHENNVHVQ-SKVAFSVTSSEDSLMDRLRELKDLGTTVFVVHLSEVIATRLFPC 247

  Fly   230 AQQVGLVTSDYRYIIGN---LDWHTMDLEPY-QHAGTNITGLRLVSPDSEQVQEVA----KALYE 286
            |:::|::...:.:|:.:   ..:|...::.. :.|...:.|.:...|.|:::....    |.|
plant   248 AEKLGMMGEGFAWILTSRSMSSFHDQFIDDLTKEAMEGVVGFKSYIPMSKELHNFTLRWRKTL-- 310

  Fly   287 SEEPFQNVS----CPLTNSMALVYDGVQLLAETYKHVNFRPVALSCNDDSAWDKGYTLVNYMKSL 347
               |.:.|:    ..|:.|....:|....||.. ..|...|...|           ||:..:|..
plant   311 ---PVEEVTGSEITRLSISGVWAHDVAWSLASA-AEVTRMPTVTS-----------TLLEAIKES 360

  Fly   348 TLNGLTGPIRFDYEGLRTDFKLEVIELAVSGMQKIGQWSGEDGFQENRPA------------PAH 400
            ...||:|..:.|...|.:| |.|::.:..||.:::|.|:....|...|..            |..
plant   361 RFKGLSGNFQLDDMKLLSD-KFEIVNMIGSGERRVGFWNSNGSFSNRRQLSSTHDNLETIIWPGG 424

  Fly   401 SLE-PDMRSL----VNKSFVVITAISE-PYGMLKETSEKLEGNDQFEGFGIELIDELSKKLGF-- 457
            |.: |..|||    ..|..|::|:.:. |..|..||..........|||.||:.........:
plant   425 SAQSPKGRSLRESGRKKLRVLVTSSNRFPRLMKVETDPITHEITIVEGFCIEVFQASIAPFNYEV 489

  Fly   458 --------------SYTWRLQEDNKYGGIDPKTGEWNGMLREIIDSRADMGITDLTMTSERESGV 508
                          :|....|:| ||                      |..:.|:|:||:|...|
plant   490 EYIRWLNGTNYTKLAYALHSQKD-KY----------------------DAAVGDITITSDRSMYV 531

  Fly   509 DFTIPFMSLGIGILFRKPMKEPPKLFSFMSPFSGEVWLWLGLAYMGVSISMFVLGRLSPAEWDNP 573
            |||:|:..:|:||:..|..    .::.|..|.:..:|:.....::...|.::::.|....|:...
plant   532 DFTLPYTEMGLGIVAAKER----SMWVFFQPLTPNLWITSAAFFVLTGIIVWLIERAENKEFQGS 592

  Fly   574 YPCIEEPTELENQFSFANCLWFSIGALLQQGSELAPKAYSTRAVAASWWFFTLILVSSYTANLAA 638
            :|         .|....  :||....|:....|......| |.|...|.|..||||:||||.|.:
plant   593 WP---------QQIGVV--IWFGFSTLVYAHREKLQHNLS-RFVVTVWVFAVLILVTSYTATLTS 645

  Fly   639 FLTVESLVTPINDADDLSKNKGGVNY--GAKIGGATFNFFKESNYPTYQRMYEFMRDNPQYMTNT 701
            .:||:.:        ..:.|:..|.:  |:.|..|.                         :||:
plant   646 MMTVQQI--------RFNANEDYVGHLSGSLIANAA-------------------------LTNS 677

  Fly   702 NQE-----GVDRVENSNYAFLMESTTIEYITERRCTLTQVGALLDE--------------KGYGI 747
            :..     |::..|  :||..:.:.::.||...   |..:..||.|              .|:|.
plant   678 SLRAMRLLGLNTSE--DYAQALMNKSVSYIVSE---LPYLKILLGENPGHFLMVKTQSTTNGFGF 737

  Fly   748 AMRKNWPYRDTLSQAVLEMQEQGLLTKMKTKWWQEKRGGGACSDADEDSGAVALEISNLGGVFLV 812
            ..:|.......:|:.:.:::....|.:|:.:|:.::    .....|:.|..:.|  ....|:|::
plant   738 MFQKGSELAPNVSREIAKLRTSERLNEMERRWFDKQ----LPYTTDDTSNPITL--YRFRGLFMI 796

  Fly   813 MGVGSFFGIFVSLLEMVLGVKER 835
            .||...|.:.|.|   :|.::||
plant   797 TGVSFAFALAVLL---ILWLRER 816

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grik	NP_001262788.1	PBP1_iGluR_Kainate	35..395	CDD:380605	77/406 (19%)
		Periplasmic_Binding_Protein_Type_2	411..781	CDD:473866	84/407 (21%)
ATGLR1.2	NP_199651.1	PBP1_GABAb_receptor_plant	41..407	CDD:380645	77/406 (19%)
		GluR_Plant	440..770	CDD:270404	83/406 (20%)