Protein Alignment Grik and GLR2.1

DIOPT Version :10

• Sequence 1: NP_001262788.1
• Gene: Grik / 42476
• FlyBaseID: FBgn0038840
• Length: 907
• Species: Drosophila melanogaster
• Sequence 2: NP_198062.2
• Gene: GLR2.1 / 832768
• AraportID: AT5G27100
• Length: 901
• Species: Arabidopsis thaliana
• Alignment Length: 995
• Identity: 198/995 - (19%)
• Similarity: 391/995 - (39%)
• Gaps: 232/995 - (23%)

  Fly    15 LGFILTSLLLAFPGCRGE------RTNVGLV------YENTDPDLEKIFHLAISKANEENEDLQL 67
            |.|::..|:..     ||      ..|||:|      |.|.   .....::::|.....:.:.|.
plant    12 LFFVIVFLMQV-----GEAQNRITNVNVGIVNDIGTAYSNM---TLLCINMSLSDFYSSHPETQT 68

  Fly    68 HGVSVSIEPGNSFET--SKKLCKMLRQNLVAVFGPTSNLAARHAMSICDAKELPFLDTRWDFGAQ 130
            ..|:..::..|...|  :..|..:..:.:.|:.||.:::.|:..:.:....::|.:    .:.|.
plant    69 RLVTTVVDSKNDVVTAAAAALDLITNKEVKAILGPWTSMQAQFMIEMGQKSQVPIV----TYSAT 129

  Fly   131 LPTI-----------------NLHPHPATLGVALRDMVVALGWESFTIIYESGEY----LPTVRE 174
            .|::                 .:|        |:::::...||.....:|....:    :|.:.:
plant   130 SPSLASIRSQYFFRATYDDSSQVH--------AIKEIIKLFGWREVAPVYVDDTFGEGIMPRLTD 186

  Fly   175 LLQMYGTAGPTVTVRRYELDLNGNYRNVLRRIRNADDFSFVVVGSMATLP--------------E 225
            :||              |:::...||.|:......|:.| |.:..|.|||              .
plant   187 VLQ--------------EINVRIPYRTVISPNATDDEIS-VELLRMMTLPTRVFVVHLVELLASR 236

  Fly   226 FFKQAQQVGLVTSDYRYIIGNLDWHTM------DLEPYQHAGTNITGLRLVSPDSEQVQEVAKAL 284
            ||.:|.::||:...|.:|:.|.....:      ::|..|    .:.|::...|.|::::.. ::.
plant   237 FFAKATEIGLMKQGYVWILTNTITDVLSIMNETEIETMQ----GVLGVKTYVPRSKELENF-RSR 296

  Fly   285 YESEEPFQNVSCPLTNSMAL-VYDGVQLLAETYKHV---NFRPVALSCNDDSAWDKGYTLVNYMK 345
            :....|..::     |...| .||....||...:..   |...|.:....:.:..:|..:..|..
plant   297 WTKRFPISDL-----NVYGLWAYDATTALALAIEEAGTSNLTFVKMDAKRNVSELQGLGVSQYGP 356

  Fly   346 SL--TLNGLTGPIRFDYEGLRTDFK----------LEVIELAVSGMQKIGQWSGEDGFQEN---R 395
            .|  ||:      |..::||..||:          .|::.:...|.:.||.|..|.|..:|   :
plant   357 KLLQTLS------RVRFQGLAGDFQFINGELQPSVFEIVNVNGQGGRTIGFWMKEYGLFKNVDQK 415

  Fly   396 PAPAHSLE-----------PDMRSLVNKSFVVIT-----AISEPYG-----MLKETSEKLEGNDQ 439
            ||...:..           |...:.|.|.:.:.|     .|..|..     .:|.|.:.:..:..
plant   416 PASKTTFSSWQDRLRPIIWPGDTTSVPKGWEIPTNGKRLQIGVPVNNTFQQFVKATRDPITNSTI 480

  Fly   440 FEGFGIELIDELSKKLGFSYTWRLQEDNKYGGIDPKTGEWNGMLREIIDSRADMGITDLTMTSER 504
            |.||.|:..:.:.:.:.:        |..|..|..:.|.::.::.::...:.|..:.|.|::|.|
plant   481 FSGFSIDYFEAVIQAIPY--------DISYDFIPFQDGGYDALVYQVYLGKYDAVVADTTISSNR 537

  Fly   505 ESGVDFTIPFMSLGIGILFRKPMKEPPKLFS--FMSPFSGEVWLWLGLAYMGVSISMFVL-GRLS 566
            ...|||::|:...|:|::.  |:|:..:..|  |:.|.:..:||...|::..:.:.::|| .|::
plant   538 SMYVDFSLPYTPSGVGLVV--PVKDSVRRSSTIFLMPLTLALWLISLLSFFIIGLVVWVLEHRVN 600

  Fly   567 PAEWDNPYPCIEEPTELENQFSFANCLWFSIGALLQQGSELAPK----AYSTRAVAASWWFFTLI 627
            | ::|.|           .|:..:...|||...::     .||:    ::..|.|...|:|..|:
plant   601 P-DFDGP-----------GQYQLSTIFWFSFSIMV-----FAPRERVLSFWARVVVIIWYFLVLV 648

  Fly   628 LVSSYTANLAAFLTVESLVTPINDADDLSKNKGGVNYGAK--IGGATFNFFKESNYPTYQRMYEF 690
            |..||||:||:.||.:.|...:.:.:.|......|.|.:.  :|....:.|.|::..:|
plant   649 LTQSYTASLASLLTTQHLHPTVTNINSLLAKGESVGYQSSFILGRLRDSGFSEASLVSY------ 707

  Fly   691 MRDNPQYMTNTNQEGVDRVENSNYAFLMESTTIEYITERRCT---LTQVGALLDEKGYGIAMRKN 752
              .:|::......:|  :.|....|.|||...:.....:.|.   :.|....:|  |.|......
plant   708 --GSPEHCDALLSKG--QAEGGVSAVLMEVPYVRIFLGQYCNKYKMVQTPFKVD--GLGFVFPIG 766

  Fly   753 WPYRDTLSQAVLEMQEQGLLTKMKTKWWQEKRGGGACSD--ADEDSGAVALEISNLGGVFLVMGV 815
            .|....:|:|:|:::|.....:::..|:  |....:|.|  .:.|        .|....|..:|.
plant   767 SPLVADISRAILKVEESNKANQLENAWF--KPIDESCPDPLTNPD--------PNPSVSFRQLGF 821

  Fly   816 GSFFGIF--------VSLLEMVLG-VKERSDENQVSFKTELLDE------IRFILQC---SGNTK 862
            .||:.:|        ::||:.|.. :||..::..:....|..:|      |:.:.:|   ||.
plant   822 DSFWVLFLVAAIVCTMALLKFVYQFLKENPNQRNLRVLWEKFNEPDQKSYIKDVTKCQCSSGQ-- 884

  Fly   863 AVKYPKNSSRSNASSKSKGS 882
              ..||| .:..|::.:.|:
plant   885 --GMPKN-GQEGANAVNNGN 901

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grik	NP_001262788.1	PBP1_iGluR_Kainate	35..395	CDD:380605	78/427 (18%)
		Periplasmic_Binding_Protein_Type_2	411..781	CDD:473866	85/391 (22%)
GLR2.1	NP_198062.2	PBP1_GABAb_receptor_plant	33..411	CDD:380645	77/423 (18%)
		GluR_Plant	452..794	CDD:270404	82/380 (22%)
		Lig_chan	574..833	CDD:459656	65/297 (22%)