Protein Alignment Grik and GLR2.6

DIOPT Version :10

• Sequence 1: NP_001262788.1
• Gene: Grik / 42476
• FlyBaseID: FBgn0038840
• Length: 907
• Species: Drosophila melanogaster
• Sequence 2: NP_001330285.1
• Gene: GLR2.6 / 830988
• AraportID: AT5G11180
• Length: 967
• Species: Arabidopsis thaliana
• Alignment Length: 954
• Identity: 187/954 - (19%)
• Similarity: 364/954 - (38%)
• Gaps: 234/954 - (24%)

  Fly    65 LQLHGVSVSI----EPGNSFET--------SKK---------LCKMLRQNLVAVFGPTSNLAARH 108
            |.|..:::|:    ...|.|:|        ||:         |..:.::.:||:.||.:::.|..
plant    51 LSLRAINMSLSEFYNTHNGFKTRIVLNIRDSKRTVVGAAASALYLIKKREVVAIIGPGNSMQAPF 115

  Fly   109 AMSICDAKELPFLDTRWDFGAQLPTINLHPHPATLGV---------ALRDMVVALGWESFTIIYE 164
            .:::.:..::|.:    .|.|..|.::....|..:..         |:..::.:..|.....||.
plant   116 LINLGNQSQVPII----SFSASSPVLDSLRSPYFIRATHDDSSQVHAISAIIESFRWREVVPIYA 176

  Fly   165 SGEY----LPTVRELLQMYGTAGPTVTVRRYELDLNGNYRNVLRRIRNADDFSFVVVGSMATLP- 224
            ..|:    ||.:.:..|              |:::...||:.: .:.:.||.....:..:.|:|
plant   177 DNEFGEGILPYLVDAFQ--------------EINVRIRYRSAI-SVHSTDDLVKKELYKLMTMPT 226

  Fly   225 -------------EFFKQAQQVGLVTSDYRYIIGN--LDWHTMDLEPYQHAGTNITGLRLVSPDS 274
                         ..|..|:::|::|..|.:|:.|  .|..::..|........:.|::.....|
plant   227 RVFIVHMLPDLGSRLFSIAKEIGMMTKGYVWIVTNGIADQMSVMGESSLENMHGVLGVKTYFSRS 291

  Fly   275 EQVQEVA---KALYESEEPFQNVSCPLTNSMALVYDGVQLLA----ETYKHVNF---RPVALSCN 329
            :::..:.   :..:..||        |.|.....||....||    |...:||.   :....:..
plant   292 KELMYLETRWRKRFGGEE--------LNNFECWGYDTATALAMSIEEISSNVNMSFSQTKRNTSR 348

  Fly   330 DDSAWD--------KGYTLVNYMKSLTLNGLTGPIRFDYEGLR---TDFKLEVIELAVSGMQKIG 383
            ||:..|        .|..|:..:.:::..|:.|  ||..:..:   |.||  ::.:..||.:.:|
plant   349 DDTGTDLDDLSFALSGPKLLQALATVSFKGVAG--RFQLKNGKLEATTFK--IVNIEESGERTVG 409

  Fly   384 QWSGEDGFQENRPAPAHSLEPDMRSL-VNKSFVVIT--------------AISEPYG-------- 425
            .|..:.|.              ::|| ||::.:.|:              .|..|.|
plant   410 FWKSKVGL--------------VKSLRVNQTGIKISHSSHRLRPIIWPGDTIFVPKGWEFPTNAK 460

  Fly   426 MLKETSEKLEGNDQF--------------EGFGIELIDELSKKLGFSYTWRL----QEDNKYGGI 472
            .|:....|.:|.:.|              .||.|::.|...:::.::..:..    ..|.|
plant   461 KLRIAVPKKDGFNNFVEVTKDANTNAPTITGFCIDVFDTAMRQMPYAVPYEYIPFETPDGK---- 521

  Fly   473 DPKTGEWNGMLREIIDSRADMGITDLTMTSERESGVDFTIPFMSLGIGILFRKPMKEPPK--LFS 535
             |: |.::.|:..:.....|..:.|.|:.:.|.:.|||.:|:...||.::.  |:|:..:  .:.
plant   522 -PR-GSYDEMVYHVFLGEFDGAVGDTTILANRSTYVDFALPYSETGIVVVV--PVKDEREKGKWV 582

  Fly   536 FMSPFSGEVWLWLGLAYMGVSISMFVLGRLSPAEWDNPYPCIEEPTELENQFSFANCLWFSIGAL 600
            |:.|.:.|:|.....:::.:.|.:::....:..::        ....:.|:.|  |..:||...|
plant   583 FLKPLTRELWFLTAASFLYIGIMVWIFEYQASGDF--------RKQSIINKIS--NVFYFSFSTL 637

  Fly   601 LQQGSELAP-KAYSTRAVAASWWFFTLILVSSYTANLAAFLTVESLVTPINDADDLSKNKGGVNY 664
            .  .:.:.| ::..||.:...|.|..|||..||||.|.:.|||:.|...:...|||  ...|||.
plant   638 F--FAHMRPSESIFTRVLVVVWCFVLLILTQSYTATLTSMLTVQELRPTVRHMDDL--RNSGVNI 698

  Fly   665 GAKIGGATFN-----FFKESNYPTY---QRMYEFMRDNPQYMTNTNQEGVDRVENSNYAFLMEST 721
            |.:.|..||.     .:|||...||   |.|:|.      ::..::..|:|       |...|..
plant   699 GYQTGSFTFERLKQMGYKESRLKTYDTPQEMHEL------FLKKSSNGGID-------AAFDEVA 750

  Fly   722 TIEYITERRCT-LTQVGALLDEKGYGIAMRKNWPYRDTLSQAVLEMQEQGLLTKMKTKWWQEKRG 785
            .::....:.|: .|.:.......|:|.|.....|....||:.:|.:.|...:..::.||   ..|
plant   751 YVKLFMAKYCSKYTIIEPTFKADGFGFAFPLGSPLVPDLSRQILNITEGETMKAIENKW---LLG 812

  Fly   786 GGACSDADEDSGAVALEISNLGGVFLVMGVGSFFGIFVSLLEMVLGVKERSDENQVSFKTELLDE 850
            ...|.|:......:.|:..:...:|.::.|.|    .:.||.|::..:.|.:..
plant   813 EKHCLDSTTSDSPIRLDHHSFEALFTIVFVVS----MLLLLAMLVCRRYRQESK----------- 862

  Fly   851 IRFILQCSGNTKAVKYPKNSSRSNASSKSKGSSMSVDSLPEDTS 894
                   ||...|     |:|.::.:.::..:..:.|::...||
plant   863 -------SGEINA-----NNSPTDGNMRAPPNQPTDDNMRAPTS 894

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grik	NP_001262788.1	PBP1_iGluR_Kainate	35..395	CDD:380605	73/400 (18%)
		Periplasmic_Binding_Protein_Type_2	411..781	CDD:473866	92/421 (22%)
GLR2.6	NP_001330285.1	PBP1_GABAb_receptor_plant	38..421	CDD:380645	73/414 (18%)
		GluR_Plant	460..810	CDD:270404	87/387 (22%)
		Lig_chan	590..842	CDD:459656	65/281 (23%)