Protein Alignment Grik and GLR3.6

DIOPT Version :10

• Sequence 1: NP_001262788.1
• Gene: Grik / 42476
• FlyBaseID: FBgn0038840
• Length: 907
• Species: Drosophila melanogaster
• Sequence 2: NP_190716.3
• Gene: GLR3.6 / 824311
• AraportID: AT3G51480
• Length: 903
• Species: Arabidopsis thaliana
• Alignment Length: 986
• Identity: 218/986 - (22%)
• Similarity: 373/986 - (37%)
• Gaps: 196/986 - (19%)

  Fly     2 WFVKMISTEASFPL-GFILTSLLLAFPGCRGERTNVGLVYENTDPDLEKIFHLAISKANEENEDL 65
            ||:.|:....:.|| |  ||.::.|.|    :..|:|.|: ..:..:.|:..:|:..|.|:
plant     3 WFLLMLIICNAVPLQG--LTKIVSARP----QVVNIGSVF-TFNSLIGKVIKVAMDAAVED---- 56

  Fly    66 QLHGVSVSIEPG----------------NSFETSKKLCKMLRQNLVAVFGPTSNLAARHAMSICD 114
                  |:..|.                |.|.:..:..:.:....||:.||..:..||....:..
plant    57 ------VNASPSILNTTTLRIIMHDTKYNGFMSIMEPLQFMESETVAIIGPQRSTTARVVAHVAT 115

  Fly   115 AKELPFLDTRWDFGAQLPTINLHPHPATLG---------VALRDMVVALGWESFTIIYESGEY-- 168
            ..::|.|    .|.|..||::....|..:.         .|:.|:|...||.....||...:|
plant   116 ELKIPIL----SFSATDPTMSPLQFPFFIRTSQNDLFQMAAIADIVQFYGWREVVAIYGDDDYGR 176

  Fly   169 --LPTVRELLQ------MYGTAGPTVTVRRYELDLNGNYRNVLRRIRNADDFSFVVVGSMATLPE 225
              :..:.:.|.      .|..|.|....|.       |..::|.::..::....||..|.....|
plant   177 NGVAALGDRLSEKRCRISYKAALPPAPTRE-------NITDLLIKVALSESRIIVVHASFIWGLE 234

  Fly   226 FFKQAQQVGLVTSDYRYIIGNLDWHTMDLEPYQHAGT--NITG---LRLVSPDSEQVQEVAKALY 285
            .|..|:.:|::::.|.:|..|.....:|.:......|  ||.|   |||.:|:|...|...
plant   235 LFNVARNLGMMSTGYVWIATNWLSTIIDTDSPLPLDTINNIQGVITLRLHTPNSIMKQNFV---- 295

  Fly   286 ESEEPFQNVSCPLTNSMAL-VYDGVQLLAET----YK---HVNF--RPVA-------LSCNDDSA 333
               :.:.|::....::.|| .||.|.|||:.    :|   :|:|  .|:.       |..:....
plant   296 ---QRWHNLTHVGLSTYALYAYDTVWLLAQAIDDFFKKGGNVSFSKNPIISELGGGNLHLDALKV 357

  Fly   334 WDKGYTLVNYMKSLTLNGLTGPIRFDYEGLRTDFKLEVIELAVSGMQKIGQWSGEDGF------- 391
            :|.|...:..:..:...||||.::|..:....:...:|:.:..:|...||.|....|.
plant   358 FDGGKIFLESILQVDRIGLTGRMKFTSDRNLVNPAFDVLNVIGTGYTTIGYWFNHSGLSVMPADE 422

  Fly   392 QENRPA----------PAHSLEPDMRSLVNKSFVVIT-----AISEPYGMLKETSEKLEGNDQFE 441
            .||...          |.||::      :.:.:|...     .|..|.....|....::.|....
plant   423 MENTSFSGQKLHSVVWPGHSIK------IPRGWVFSNNGRHLRIGVPNRYRFEEVVSVKSNGMIT 481

  Fly   442 GFGIELIDELSKKLGFSYTWRLQEDNKYGGIDPKTGEWNGMLREIIDSRADMGITDLTMTSERES 506
            ||.:::.......|.::..:.|..... |..:|...|   ::|.|.....|.|:.|:|:.:||..
plant   482 GFCVDVFIAAINLLPYAVPFELVAFGN-GHDNPSNSE---LVRLITTGVYDAGVGDITIITERTK 542

  Fly   507 GVDFTIPFMSLGIGILFRKPMKE-PPKLFSFMSPFSGEVWLWLGLAYMGVSISMFVLGRLSPAEW 570
            ..|||.|::..|:.::  .|::: .....:|:.||:.::||....:::.|...::.|......|:
plant   543 MADFTQPYVESGLVVV--APVRKLGSSAMAFLRPFTPQMWLIAAASFLIVGAVIWCLEHKHNDEF 605

  Fly   571 DNPYPCIEEPTELENQFSFANCLWFSIGALLQQGSELAPKAYSTRAVAASWWFFTLILVSSYTAN 635
            ..|      |..     ......|||...|.....|....... |.|...|.|..||:.|||||:
plant   606 RGP------PRR-----QVITTFWFSFSTLFFSHRETTTSNLG-RIVLIIWLFVVLIINSSYTAS 658

  Fly   636 LAAFLTVESLVTPINDADDLSKNKGGVNYGAKIGGATFNFFKE----------SNYPTYQRMYEF 690
            |.:.|||..|.:||...:.|..|...:.|      ...:|.::          |.....:...|:
plant   659 LTSILTVHQLSSPIKGIETLQTNHDPIGY------PQGSFVRDYLIHELNIHVSRLVPLRSPEEY 717

  Fly   691 ---MRDNPQYMTNTNQEGVDRVENSNYAFLMESTTIEYITERRCTLTQVGALLDEKGYGIAMRKN 752
               :||.|      .:.||..|.:       |...||.....||....||....:.|:|.|..:|
plant   718 DKALRDGP------GKGGVAAVVD-------ERAYIELFLSNRCEFGIVGQEFTKNGWGFAFPRN 769

  Fly   753 WPYRDTLSQAVLEMQEQGLLTKMKTKWWQEKRGGGACSDADEDSGAVALEISNLGGVFLVMGVGS 817
            .|....:|.|:|::.|.|.:.:::.||...|    |||....:.....||:.:..|:|:|.||..
plant   770 SPLAVDVSAAILQLSENGDMQRIRDKWLLRK----ACSLQGAEIEVDRLELKSFWGLFVVCGVAC 830

  Fly   818 FFGIFVSLLEMV--LGVK-----ERSDENQVSFKTELLDEIRFILQCSGNTKAVKYPKNSSR--- 872
            ...:.|..:.|:  .|.:     |.|...:.|....:...:.|:.:...:.||     .|||
plant   831 VLALAVYTVLMIRQFGQQCPEEAEGSIRRRSSPSARIHSFLSFVKEKEEDAKA-----RSSRERQ 890

  Fly   873 -----SNASSK 878
                 :|.||:
plant   891 LEDISANGSSR 901

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grik	NP_001262788.1	PBP1_iGluR_Kainate	35..395	CDD:380605	88/423 (21%)
		Periplasmic_Binding_Protein_Type_2	411..781	CDD:473866	90/388 (23%)
GLR3.6	NP_190716.3	PBP1_GABAb_receptor_plant	31..419	CDD:380645	87/416 (21%)
		GluR_Plant	458..797	CDD:270404	88/375 (23%)
		Lig_chan	576..829	CDD:459656	71/287 (25%)