Protein Alignment Grik and GLR3.5

DIOPT Version :10

• Sequence 1: NP_001262788.1
• Gene: Grik / 42476
• FlyBaseID: FBgn0038840
• Length: 907
• Species: Drosophila melanogaster
• Sequence 2: NP_001324013.1
• Gene: GLR3.5 / 817800
• AraportID: AT2G32390
• Length: 953
• Species: Arabidopsis thaliana
• Alignment Length: 1012
• Identity: 225/1012 - (22%)
• Similarity: 389/1012 - (38%)
• Gaps: 189/1012 - (18%)

  Fly     1 MWFVKMISTEASFPLGFILTSL----LLAFPGCRGE-------------RTNVGLVYENTDPDLE 48
            |.|..||   ....:||:|..:    :|...|...|             ..|||.:: ..|..:.
plant     1 MGFFVMI---RDVSMGFMLLCISALWVLPIQGAGRESFSRNSSSSSLPSSVNVGALF-TYDSFIG 61

  Fly    49 KIFHLAISKANEE-NEDLQ-LHGVSVSI--EPGN--SFETSKKLCKMLRQNLVAVFGPTSNLAAR 107
            :...||...|.|: |.|.. |.|..::|  :..|  .|..:....:::...:||..||.|:....
plant    62 RAAKLAFVAAIEDINADQSILRGTKLNIVFQDTNCSGFVGTMGALQLMENKVVAAIGPQSSGIGH 126

  Fly   108 HAMSICDAKELPFLDTRWDFGAQLPTINLHPHPATLGV---------ALRDMVVALGWESFTIIY 163
            ....:.:...:|||    .|.|..||::...:|..|..         |:.|.|....|.....|:
plant   127 IISHVANELHVPFL----SFAATDPTLSSLQYPYFLRTTQNDYFQMNAITDFVSYFRWREVVAIF 187

  Fly   164 ESGEYLPTVRELLQMYGTAGPTVTVRRYELDL---------NGNYRNVLRRIRNADDFSFVVVGS 219
            ...||   .|..:.:.|.|   :..:|.::..         |.:..::|..:...:...|||..:
plant   188 VDDEY---GRNGISVLGDA---LAKKRAKISYKAAFPPGADNSSISDLLASVNLMESRIFVVHVN 246

  Fly   220 MATLPEFFKQAQQVGLVTSDYRYIIGNLDW--HTMD-LEPYQHAGTN----ITGLRLVSPDSEQV 277
            ..:....|..|:.:|::.|.|.:|  ..||  ..:| :||......:    :...|..:|:|:..
plant   247 PDSGLNIFSVAKSLGMMGSGYVWI--TTDWLLTALDSMEPLDPRALDLLQGVVAFRHYTPESDNK 309

  Fly   278 QEVA--------KALYESEEPFQNVSCPLTNSMAL-VYDGVQLLAETY-------KHVNFR--PV 324
            ::..        |...:|::.|        ||.|| .||.|.|:|...       ..|.|.  |.
plant   310 RQFKGRWKNLRFKESLKSDDGF--------NSYALYAYDSVWLVARALDVFFSQGNTVTFSNDPS 366

  Fly   325 ALSCNDDS-------AWDKGYTLVNYMKSLTLNGLTGPIRFDYEGLRTDFKLEVIELAVSGMQKI 382
            ..:.||..       .:::|...:..:..:...||||.|.|:.|..|.:...:::.:..:|..::
plant   367 LRNTNDSGIKLSKLHIFNEGERFLQVILEMNYTGLTGQIEFNSEKNRINPAYDILNIKSTGPLRV 431

  Fly   383 GQWSGEDGFQENRP-----APAHSLEPDMRSLVNKSFVVITAISEPYGML--------------- 427
            |.||...||....|     .|:::...|.|  :|:.......|..|.|.:
plant   432 GYWSNHTGFSVAPPETLYSKPSNTSAKDQR--LNEIIWPGEVIKPPRGWVFPENGKPLKIGVPNR 494

  Fly   428 ---KETSEKLEGNDQFEGFGIELIDELSKKLGFSY--TWRLQEDNKYGGIDPKTGEWNGMLREII 487
               |..:.|.:.....:||.|::.:...:.|.:..  |:.|..|.|      |...::.::.|:.
plant   495 VSYKNYASKDKNPLGVKGFCIDIFEAAIQLLPYPVPRTYILYGDGK------KNPSYDNLISEVA 553

  Fly   488 DSRADMGITDLTMTSERESGVDFTIPFMSLGIGILFR-KPMKEPPKLFSFMSPFSGEVWLWLGLA 551
            .:..|:.:.|:|:.:.|...||||.||:..|:.::.. |..|..|  :||:.||:.|:|...|..
plant   554 ANIFDVAVGDVTIITNRTKFVDFTQPFIESGLVVVAPVKGAKSSP--WSFLKPFTIEMWAVTGAL 616

  Fly   552 YMGVSISMFVLGRLSPAEWDNPYPCIEEPTELENQFSFANCLWFSIGALLQQGSELAPKAYST-- 614
            ::.|...:::|......|:..|      |..     ......|||...:.....|   ...||
plant   617 FLFVGAVIWILEHRFNEEFRGP------PRR-----QIITVFWFSFSTMFFSHRE---NTVSTLG 667

  Fly   615 RAVAASWWFFTLILVSSYTANLAAFLTVESLVTPINDADDLSKNKGGVNYGAKIGGATFNFFKES 679
            |.|...|.|..||:.|||||:|.:.|||:.|.:.|...|.|..:...:  |.:.|...:.|....
plant   668 RFVLLVWLFVVLIINSSYTASLTSILTVQQLTSRIEGMDTLIASNEPI--GVQDGTFAWKFLVNE 730

  Fly   680 NYPTYQRMYEFMRDNPQYMTNTNQEGVDRVENSNYAFLMESTTIEYI----TERRCTLTQVGALL 740
            ......|:.. ::|..:|: :..|.|   ......|.:::.  :.||    :...|....||...
plant   731 LNIAPSRIIP-LKDEEEYL-SALQRG---PRGGGVAAIVDE--LPYIKALLSNSNCKFRTVGQEF 788

  Fly   741 DEKGYGIAMRKNWPYRDTLSQAVLEMQEQGLLTKMKTKWWQEKRGGGACSDADEDSGAVALEISN 805
            ...|:|.|.:::.|....:|.|:|::.|:|.|.|::.||.....   .|:....|:....:.:.:
plant   789 TRTGWGFAFQRDSPLAVDMSTAILQLAEEGKLEKIRKKWLTYDH---ECTMQISDTENYQISVQS 850

  Fly   806 LGGVFLVMGVGSFFGIFVSLLEMVLGVK----ERSDENQ----------------VSFKTELLDE 850
            ..|:||:.||..|..:.:...::....:    |.|||.|                ||||    |.
plant   851 FWGLFLICGVVWFIALTLFCWKVFWQYQRLRPEESDEVQARSEEAGSSRGKSLRAVSFK----DL 911

  Fly   851 IRFILQCSGNTKAVKYPKNSSRSNASSKSKGSSMSVD 887
            |:.:.:.....|.:...|:|.:......|..:|.|.|
plant   912 IKVVDKREAEIKEMLKEKSSKKLKDGQSSAENSQSKD 948

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grik	NP_001262788.1	PBP1_iGluR_Kainate	35..395	CDD:380605	91/415 (22%)
		Periplasmic_Binding_Protein_Type_2	411..781	CDD:473866	94/396 (24%)
GLR3.5	NP_001324013.1	PBP1_GABAb_receptor_plant	49..444	CDD:380645	91/415 (22%)
		GluR_Plant	485..828	CDD:270404	89/373 (24%)