Protein Alignment Grik and GLR2.9

DIOPT Version :10

• Sequence 1: NP_001262788.1
• Gene: Grik / 42476
• FlyBaseID: FBgn0038840
• Length: 907
• Species: Drosophila melanogaster
• Sequence 2: NP_001325277.1
• Gene: GLR2.9 / 817458
• AraportID: AT2G29100
• Length: 942
• Species: Arabidopsis thaliana
• Alignment Length: 957
• Identity: 210/957 - (21%)
• Similarity: 377/957 - (39%)
• Gaps: 191/957 - (19%)

  Fly     6 MISTEASFPLGFILTSLLLAFPGCRGERTN---VGLVYE-NTDPDLEKI----FHLAISKANEEN 62
            |:.|..:| |.:.:...||...|....:|:   ||:|.: ||  ...||    ..:|:|....::
plant     2 MMKTNNTF-LSYFVCGFLLMGVGLGQNQTSEIKVGVVLDLNT--TFSKICLTSIKMAVSDFYADH 63

  Fly    63 ED----LQLHGVSVSIEPGNSFETSKKLCKMLR-QNLVAVFGPTSNLAARHAMSICDAKELPFLD 122
            .:    |.|| |..|:|  ::.:.|.....::: :.:.|:.||.:::.|...:.:.:..::|.:
plant    64 PNYLTRLTLH-VRDSME--DTVQASAAALDLIKTEQVSAIIGPINSMQADFMIKLANKTQVPTI- 124

  Fly   123 TRWDFGAQLPTINLHPHP----ATLGVALRDMVVA-----LGWESFTIIY---ESGE-YLPTVRE 174
               .|.|..|.:.....|    ||:..:.:...:|     ..|.....||   |.|| ::|.:.:
plant   125 ---TFSATSPLLTSIKSPYFVRATIDDSSQVRAIASIFKFFRWRRVVAIYVDNEFGEGFMPFLFD 186

  Fly   175 LLQMYGTAGPTVTVRRYELD---LNGNYRNVLRRIRNADDFSFVVVGSMATLPEFFKQAQQVGLV 236
            .||       .|.|:|..:.   ::...:..||::.......|||....:.....|:.|:.:|::
plant   187 ALQ-------DVEVKRSVIPPEAIDDEIQKELRKLMERQARVFVVHMESSLALRVFQIARDIGMM 244

  Fly   237 TSDYRYIIGNLDWHTMDLEPYQHAGT--------NITGLRLVSPDSEQVQEVA---KALYESEEP 290
            ...|.:::.|...|.|     :|...        .:.|:|...|.|:::.:..   |..:|.|.|
plant   245 EEGYVWLMTNGMTHMM-----RHINNGRSLNTIEGVLGVRSHVPKSKELGDFRLRWKRTFEKENP 304

  Fly   291 FQNVSCPLTNSMAL-VYDGVQLLAETYKHVNFRPVALSCNDDSAW-DKGYTLVNYMKSLTLNG-- 351
            .....   .|..|| .||.:..||:..:..|.:         |.| |.|.||......|...|
plant   305 SMRDD---LNVFALWAYDSITALAKAVEKANTK---------SLWYDNGSTLSKNRTDLGNVGVS 357

  Fly   352 LTGP--------IRFDYEGLRTDFKL----------EVIELAVSGMQKIGQWSGEDGFQE----N 394
            |.||        :||:  ||..:|||          |:|....:..:.||.|:..||..:    |
plant   358 LYGPSLQKAFSEVRFN--GLAGEFKLIDGQLQSPKFEIINFVGNEERIIGFWTPRDGLMDATSSN 420

  Fly   395 RPAPAHSLEPDMRSLVNKSFVV---ITAISEP-----YGMLKETSEKLEGNDQFEGFGIELIDEL 451
            :......:.|....:|.|.:.:   ...:..|     :..:|.|...:.......|:.||:.:..
plant   421 KKTLGPVIWPGKSKIVPKGWEIPGKKLRVGVPMKKGFFDFVKVTINPITNKKTPTGYAIEIFEAA 485

  Fly   452 SKKLGF----SYTWRLQEDNKYGGIDPKTGEWNGMLREIIDSRADMGITDLTMTSERESGVDFTI 512
            .|:|.:    .|. ..:..|.|          |.::.::.|...|..:.|:|:|:.|....|||:
plant   486 LKELPYLVIPEYV-SFESPNNY----------NNLVYQVYDKTWDAVVGDITITANRSLYADFTL 539

  Fly   513 PFMSLGIGILFRKPMKEPPKLFSFMSPFSGEVWLWLGLAYMGVSISMFVLGRLSPAEWDNPYPCI 577
            ||...|:.::......|....:.|:.|:|.|:|:..|..::.:...:::.......::..|
plant   540 PFTESGVSMMVPVRDNENKDTWVFLEPWSLELWVTTGCFFVFIGFVVWLFEHRVNTDFRGP---- 600

  Fly   578 EEPTELENQFSFANCLWFSIGALL-----QQGSELAPKAYSTRAVAASWWFFTLILVSSYTANLA 637
                   .|:.....||||...::     ...|.||      |.|...|.|..|:|..||||:|.
plant   601 -------PQYQIGTSLWFSFSTMVFAHRENVVSNLA------RFVVVVWCFVVLVLTQSYTASLT 652

  Fly   638 AFLTVESLVTPINDADDLSKNKGGVNYGAKIGGATFNFFKE-----SNYPTYQRMYEFMRDNPQY 697
            :||||:||...:.:.:||.||:..|.|.   |||   |.|:     ..:....:.::..:|....
plant   653 SFLTVQSLQPTVTNVNDLIKNRDCVGYQ---GGA---FVKDILLGLGFHEDQLKPFDSAKDADDL 711

  Fly   698 MTNTNQEGVDRVENSNYAFLMESTTIEYITERRCT-LTQVGALLDEKGYGIAMRKNWPYRDTLSQ 761
            ::....:|:       .|...|...::.|..:.|: ...|.......|:|.|..||.|.....|:
plant   712 LSKGKSKGI-------AAAFDEVAYLKAILSQSCSKYVMVEPTFKTGGFGFAFPKNSPLTGEFSR 769

  Fly   762 AVLEMQEQGLLTKMKTKWWQEKRGGGACSDADEDSGAVALEISNLGGVFLVMGVGSFFG--IFVS 824
            |:|.:.:..:..:::.:|:.:|..   |.|......:..|.:|:..|:||:.|....|.  :||:
plant   770 AILNLTQNNVTQQIEDRWFPKKND---CPDPMTALSSNRLNLSSFLGLFLIAGTAISFSLLVFVA 831

  Fly   825 L--------------------LEMVLGVKERSDENQVSFKTELLDEI 851
            |                    |:.:..:.:..|.|..:||...:..|
plant   832 LFLYEHRHTLGDDSEDSLWRKLKFLFKIFDEKDMNSHTFKNSAIHNI 878

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grik	NP_001262788.1	PBP1_iGluR_Kainate	35..395	CDD:380605	94/425 (22%)
		Periplasmic_Binding_Protein_Type_2	411..781	CDD:473866	86/392 (22%)
GLR2.9	NP_001325277.1	PBP1_GABAb_receptor_plant	33..415	CDD:380645	94/416 (23%)
		GluR_Plant	445..788	CDD:270404	84/383 (22%)
		Lig_chan	568..821	CDD:459656	67/285 (24%)