Protein Alignment Grik and GLR2

DIOPT Version :10

• Sequence 1: NP_001262788.1
• Gene: Grik / 42476
• FlyBaseID: FBgn0038840
• Length: 907
• Species: Drosophila melanogaster
• Sequence 2: NP_001318239.1
• Gene: GLR2 / 816231
• AraportID: AT2G17260
• Length: 925
• Species: Arabidopsis thaliana
• Alignment Length: 996
• Identity: 211/996 - (21%)
• Similarity: 401/996 - (40%)
• Gaps: 206/996 - (20%)

  Fly     6 MISTEASFPLGFILT---SLLLAFPGCRGER---TNVGLVYENTDPDLEKIF----HLAISKANE 60
            |:|:.....|.||:.   .|||: .|....|   ..||.::     .|..::    ::|...|.|
plant     1 MLSSMNWVLLSFIIVLGGGLLLS-EGASSSRPPVIKVGAIF-----GLNTMYGETANIAFKAAEE 59

  Fly    61 E-NEDLQLHG-----VSVSIEPGNSFETSKKLCKMLRQNLVAVFGPTSNLAARHAMSICDAKELP 119
            : |.|....|     :.::....:.|.:.....:.:..::||:.||.:::.|.....:.:...:|
plant    60 DVNSDPSFLGGSKLRILMNDAKRSGFLSIMGALQFMETDVVAIIGPQTSIMAHVLSHLANELTVP 124

  Fly   120 FLDTRWDFGAQLPTIN-------LHPHPATLGV--ALRDMVVALGWESFTIIYESGEYLPTVREL 175
            .|    .|.|..||::       :...|:.|.:  |:.:|:...||.....:|...:........
plant   125 ML----SFTALDPTLSPLQFPFFVQTAPSDLFLMRAIAEMITYYGWSDVVALYNDDDNSRNGVTA 185

  Fly   176 LQMYGTAGPTVTVRRYELDLNGNYRNVLR----------------RIRNADDFSFVVVGSMATLP 224
            |      |..:..||.::    :|:.||.                :||..:  |.|:|  :.|.|
plant   186 L------GDELEERRCKI----SYKAVLPLDVVITSPVEIIEELIKIRGME--SRVIV--VNTFP 236

  Fly   225 E----FFKQAQQVGLVTSDYRYIIGNLDWHTMDLEPYQHAGTNITG----LRLVSPDSEQVQEVA 281
            .    .||:|:::|::...|.:|.  ..|.:..|:......|.:..    |||.:|||.:.::.|
plant   237 NTGKMIFKEAERLGMMEKGYVWIA--TTWLSSVLDSNLPLDTKLVNGVLTLRLHTPDSRKKRDFA 299

  Fly   282 KALYESEEPFQNVSCPLTNSMAL--------VYDGVQLLAETYKHV----------------NFR 322
             |.::::         |:|:..:        .||.|.::|...|.:                :.:
plant   300 -ARWKNK---------LSNNKTIGLNVYGLYAYDTVWIIARAVKTLLEAGGNLSFSNDAKLGSLK 354

  Fly   323 PVALSCNDDSAWDKGYTLVNYMKSLTLNGLTGPIRFDYEGLRTDFKLEVIELAVSGMQKIGQWSG 387
            ..||:.:..|.:|:|..|::|:....::|||||::|..:........::|.|....:.:||.||.
plant   355 GEALNLSALSRFDQGSQLLDYIVHTKMSGLTGPVQFHPDRSMLQPSYDIINLVDDRVHQIGYWSN 419

  Fly   388 EDGFQENRPAPAHSLEPDMRSLVNKSFVVITAISEPYG-------------------------ML 427
            ..|.....|...:| :|..||..|:.   :.:::.|.|                         ..
plant   420 YSGLSIVPPESFYS-KPPNRSSSNQH---LNSVTWPGGTSVTPRGWIFRNNGRRLRIGVPDRASF 480

  Fly   428 KETSEKLEG-NDQFEGFGIELIDELSKKLGFSYTWRLQEDNKYGGIDPKTGEWNGMLREI---ID 488
            |:...::.| :::.:|:.|::.:...|.|.:.    :..:..:.|.......:|.::.::   :|
plant   481 KDFVSRVNGSSNKVQGYCIDVFEAAVKLLSYP----VPHEFIFFGDGLTNPNYNELVNKVTTGVD 541

  Fly   489 SRADMGITDLTMTSERESGVDFTIPFMSLGIGILFRKP---MKEPPKLFSFMSPFSGEVWLWLGL 550
            ..|.:|  |:.:.::|...||||.|::..|:.::  .|   :.|.|  ::|:.||:..:|
plant   542 FDAVVG--DIAIVTKRTRIVDFTQPYIESGLVVV--APVTRLNENP--WAFLRPFTLPMW----- 595

  Fly   551 AYMGVSISMFVLGRLSPAEWDNPYPCIEEPTELENQF------SFANCLWFSIGALLQQGSELAP 609
               .|:.|.||:  :..|.|     .:|.  .:.::|      .....|||:...:.....|...
plant   596 ---AVTASFFVI--VGAAIW-----ILEH--RINDEFRGPPRRQIITILWFTFSTMFFSHRETTV 648

  Fly   610 KAYSTRAVAASWWFFTLILVSSYTANLAAFLTVESLVTPINDADDLSKNKGGVNYGAKIGGATFN 674
            .... |.|...|.|..||:.|||||:|.:.|||:.|.:||...|.|..:.|.:  |.::|....|
plant   649 STLG-RMVLLIWLFVVLIITSSYTASLTSILTVQQLNSPIKGVDTLISSTGRI--GFQVGSFAEN 710

  Fly   675 FFKESNYPTYQRMYEFMRDNPQYMTNTNQEGVDRVENSNYAFLMESTTIEYITERRCTLTQVGAL 739
            :..:.......|:....  :|:...|..|.|      :..|.:.|...|:......|.....|..
plant   711 YMTDELNIASSRLVPLA--SPEEYANALQNG------TVAAIVDERPYIDLFLSDYCKFAIRGQE 767

  Fly   740 LDEKGYGIAMRKNWPYRDTLSQAVLEMQEQGLLTKMKTKWWQEKRGGGACSD--ADEDSGAVALE 802
            ....|:|.|..::.|....:|.|:|.:.|.|.|.|:..:|..:..    ||.  ..:...:..|.
plant   768 FTRCGWGFAFPRDSPLAVDMSTAILGLSETGELQKIHDRWLSKSN----CSSPHGSQSGDSEQLN 828

  Fly   803 ISNLGGVFLVMGVGSFFGIFVSLLEMV---------LGVKERSDENQVSFKTELLDEIRFILQCS 858
            :.:..|:|||:|:.....:|:...:::         :.|:|.....:.|..|:|...:.|:.:..
plant   829 VHSFWGMFLVVGIACLVALFIHFFKIIRDFCKDTPEVVVEEAIPSPKSSRLTKLQTFLAFVDEKE 893

  Fly   859 GNTK-AVKYPKNSSRS-NASS 877
            ..|| .:|..:|:..| ||:|
plant   894 EETKRRLKRKRNNDHSMNANS 914

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grik	NP_001262788.1	PBP1_iGluR_Kainate	35..395	CDD:380605	86/426 (20%)
		Periplasmic_Binding_Protein_Type_2	411..781	CDD:473866	87/407 (21%)
GLR2	NP_001318239.1	PBP1_GABAb_receptor_plant	35..427	CDD:380645	86/426 (20%)
		GluR_Plant	468..808	CDD:270404	83/377 (22%)
		Lig_chan	591..842	CDD:459656	67/282 (24%)