Protein Alignment Grik and grin3ba

DIOPT Version :10

• Sequence 1: NP_001262788.1
• Gene: Grik / 42476
• FlyBaseID: FBgn0038840
• Length: 907
• Species: Drosophila melanogaster
• Sequence 2: XP_021323058.1
• Gene: grin3ba / 566411
• ZFINID: ZDB-GENE-070912-354
• Length: 1118
• Species: Danio rerio
• Alignment Length: 979
• Identity: 225/979 - (22%)
• Similarity: 375/979 - (38%)
• Gaps: 245/979 - (25%)

  Fly    42 NTDPDLEKIFHLAISKANEENEDLQLHGVSVSIEPGNSFETSKKLCKMLRQNLVAVFGPTSNLAA 106
            |.||  |.:|....       :|:.:.|||..:    :|..|       .:.|:.|...:|.|
Zfish    92 NGDP--ESMFRCVC-------QDIVVQGVSAVL----AFPQS-------HEELIQVEFMSSFL-- 134

  Fly   107 RHAMSICDAKELPF---------LDTRWDFGAQLPTINLHPHPATLGVALRDMVVAL----GWES 158
                      |:||         |.|:..|..|:.| .:.|.      .|.|:::|:    ||:.
Zfish   135 ----------EIPFISIIEQGEPLKTQNRFHLQMMT-RMPPS------GLSDLLLAVLLRGGWQG 182

  Fly   159 FTIIYESGEYLPTVRELLQMYGTAG---------PTVTVRRYELDLNGN-----YRNVLRRIRNA 209
            .......|.....:.|.||..|..|         .|:.:.|.|.:::.:     ...:|.|..:|
Zfish   183 GAATVCPGGGNTGMLEELQQRGHLGLDGAHWHLWETLNLSRLEENISEDKVMELLSQLLSRTPSA 247

  Fly   210 DDFSFVVVGS----MATLPEFFKQAQQVGLVTSDYRYIIGNLDWHTMDLEPYQHAGTNITGLRLV 270
            ...|.|:.||    .||:   ...|.|:........:|:|    :.:.|:.....|:.: ||...
Zfish   248 PASSVVLFGSDPECTATV---LHCAHQLSGTLPPMHWIMG----YPLSLDSLHSIGSPL-GLMAY 304

  Fly   271 SPDSEQVQEVAKALYESEEPFQNVSCPLTNSMALVYDGVQLLAE-TYKHVNFRP-VALSCNDDSA 333
            .       ||.:.             ||.   ..:.|.:||:.. .|.....|| :||..|..:.
Zfish   305 G-------EVNRK-------------PLN---FYIRDTLQLIGRAVYAATMVRPDLALIQNMVNC 346

  Fly   334 WDK---------GYTLVNYMKSLTLNGLTGPIRFD--YEGLRTDFKLEVIELA------------ 375
            :||         |..|..::.:.:..|||||:|.:  :..:.|..:..:..|.
Zfish   347 FDKPNKHELPSSGQYLARFLSNTSFTGLTGPVRVERSFSRVLTSQRFHIWSLQRDPLGQPSWVTV 411

  Fly   376 ---VSG---MQKIGQWSG------EDG--------FQENRPAPAHSLEPDMRSLVNKSFVVITAI 420
               .||   :::.|.|.|      |||        :|...|.....|.  :.:||...||....:
Zfish   412 ASWQSGRLELEEQGLWPGVTQHQREDGPGIRLGGRWQAGLPVAGSRLR--VVTLVEHPFVFTREV 474

  Fly   421 SE----PYGML-----KETSEKLEGNDQFE-------------------GFGIELIDELSKKLGF 457
            .|    |.|.|     ...||.|  |..|.                   |:.|:|:::|::.:.|
Zfish   475 DEEGQCPAGQLCLDPQTNNSEVL--NQLFRELEQTNSSSLPTDMRKCCYGYCIDLLEKLAEDMHF 537

  Fly   458 SYTWRLQEDNKYGGIDPKTGEWNGMLREIIDSRADMGITDLTMTSERESGVDFTIPFMSLGIGIL 522
            .:...:..|.|||..  |.|.|:|::.:::...|||.:|..::.|.|...:|||.||.|..:|||
Zfish   538 EFDLYIVGDGKYGAW--KGGRWSGLVGDLLSGVADMAVTSFSINSARSRVIDFTSPFFSTSLGIL 600

  Fly   523 FRKPMKEPPKLFSFMSPFSGEVW--LWLGLAYMGVSISMFVLGRLSPAEWDNPYPCIEEPTELEN 585
            .|......| :.:||.|....:|  :::.|....:.|:::        ||::|:...........
Zfish   601 VRSKDTAAP-IGAFMWPLHWSMWVGIFVALHITALFITLY--------EWNSPFGMTPHGRNRIR 656

  Fly   586 QFSFANCLWFSIGALLQQGSELA---PKAYSTRAVAASWWFFTLILVSSYTANLAAFLTVESLVT 647
            .||:::.|......|.  |..:|   ||.::.|.:...|..|.|:::|||||||||.:..|....
Zfish   657 VFSYSSALNLCYAILF--GRTVASKTPKCWTGRFLMNLWAIFCLLVLSSYTANLAAVMVGEKTFE 719

  Fly   648 PINDADDLSKNKG--GVNYGAKIGGATFNFFKESNYPTYQRMYEFMRDNPQYMTNTNQEGVDRVE 710
            .::...|:..:..  |..:|.....:..::.|:|    :..|:|:||   ::...|..:||..::
Zfish   720 EVSGIHDVKLHHPSLGFRFGTVRESSAEDYVKKS----FPEMHEYMR---RFNKPTTPDGVSTLK 777

  Fly   711 NSN---YAFLMESTTIEY--ITERRCTLTQVGALLDEKGYGIAMRKNWPYRDTLSQAVLEMQEQG 770
            ...   .||:|:...::|  ..:..|.|..||.....:||||.:.:|.|....:|:.|...:..|
Zfish   778 TDPPQLDAFIMDKALLDYEVSIDADCKLLTVGKPFAIEGYGIGLPQNSPLTRNVSEYVSRYKSDG 842

  Fly   771 LLTKMKTKWWQEKRGGGACSDADEDSGAVALEISNLGGVFLVMGVGSFFGIFVSLLEMVLGVKER 835
            .:..:..||::....|.......|.               |.||:..|.|:||.|...|.|.
Zfish   843 YMDMLHDKWYKVVPCGKRVFAVTET---------------LQMGIQHFSGLFVLLCVGVAGA--- 889

  Fly   836 SDENQVSFKTELLDE---IRFILQCSGNTKAVKYPKNSSRSNASSKSKGSSMSVDSLPEDTSEAD 897
                    ...||.|   .||||....:.:..||..::|:    ...:..:|..|.  |..|||:
Zfish   890 --------LLTLLGEHAFFRFILPHLRHQQRFKYWLHTSQ----KIHRAINMGCDD--ERKSEAE 940

  Fly   898 ASGK 901
            :|.:
Zfish   941 SSDR 944

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grik	NP_001262788.1	PBP1_iGluR_Kainate	35..395	CDD:380605	89/428 (21%)
		Periplasmic_Binding_Protein_Type_2	411..781	CDD:473866	103/409 (25%)
grin3ba	XP_021323058.1	Periplasmic_Binding_Protein_type1	36..427	CDD:471960	83/404 (21%)
		PBP2_iGluR_NMDA_Nr3	457..852	CDD:270438	105/418 (25%)
		Lig_chan	618..885	CDD:459656	69/298 (23%)