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Protein Alignment Grik and Grik2

DIOPT Version :9

Sequence 1:	NP_001262788.1	Gene:	Grik / 42476	FlyBaseID:	FBgn0038840	Length:	907	Species:	Drosophila melanogaster
Sequence 2:	NP_062182.1	Gene:	Grik2 / 54257	RGDID:	2733	Length:	908	Species:	Rattus norvegicus

Alignment Length:	840	Identity:	328/840 - (39%)
Similarity:	494/840 - (58%)	Gaps:	42/840 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 EKIFHLAISKANEE-----NEDLQLHGVSVSIEPGNSFETSKKLCKMLRQNLVAVFGPTSNLAAR 107
            |..|..|::..|..     |..|......:::.  :|||.|||.|..|...:.|:|||:.:.:|.
  Rat    54 ELAFRFAVNTINRNRTLLPNTTLTYDTQKINLY--DSFEASKKACDQLSLGVAAIFGPSHSSSAN 116

  Fly   108 HAMSICDAKELPFLDTRWDFGAQLPT------INLHPHPATLGVALRDMVVALGWESFTIIYESG 166
            ...|||:|..:|.:.|||..  |:..      ::|:|..::|..|:.|:|....|::.|::|:..
  Rat   117 AVQSICNALGVPHIQTRWKH--QVSDNKDSFYVSLYPDFSSLSRAILDLVQFFKWKTVTVVYDDS 179

  Fly   167 EYLPTVRELLQMYGTAGPTVTVRRYELDLNGNYRNVLRRIRNADDFSFVVVGSMATLPEFFKQAQ 231
            ..|..::||::........:.:|:...|.. :.:.:|:.::...:|..:...|........|||.
  Rat   180 TGLIRLQELIKAPSRYNLRLKIRQLPADTK-DAKPLLKEMKRGKEFHVIFDCSHEMAAGILKQAL 243

  Fly   232 QVGLVTSDYRYIIGNLDWHTMDLEPYQHAGTNITGLRLVSPDSEQVQEVAKALYESEEPFQNVSC 296
            .:|::|..|.||...||...:|:|||:::|.|:||.|:::.::.||..:.:..  |.|..|....
  Rat   244 AMGMMTEYYHYIFTTLDLFALDVEPYRYSGVNMTGFRILNTENTQVSSIIEKW--SMERLQAPPK 306

  Fly   297 P--------LTNSMALVYDGVQLLAETYKHVNFRPV-ALSCNDDSAWDKGYTLVNYMKSLTLNGL 352
            |        :|...||:||.|.:::...:......| :|.||....|..|...::.:|.....||
  Rat   307 PDSGLLDGFMTTDAALMYDAVHVVSVAVQQFPQMTVSSLQCNRHKPWRFGTRFMSLIKEAHWEGL 371

  Fly   353 TGPIRFD-YEGLRTDFKLEVIELAVSGMQKIGQW---SGEDGFQENRPAPAHSLEPDMRSLVNKS 413
            ||.|.|: ..||||||.|:||.|...|::|||.|   ||.:..:..:..||:..:    ||.|:|
  Rat   372 TGRITFNKTNGLRTDFDLDVISLKEEGLEKIGTWDPASGLNMTESQKGKPANITD----SLSNRS 432

  Fly   414 FVVITAISEPYGMLKETSEKLEGNDQFEGFGIELIDELSKKLGFSYTWRLQEDNKYGGIDPKTGE 478
            .:|.|.:.|||.:.|::.:.|.|||:|||:.|:|:.|||..|||:|..||.||.|||..|...|:
  Rat   433 LIVTTILEEPYVLFKKSDKPLYGNDRFEGYCIDLLRELSTILGFTYEIRLVEDGKYGAQDDVNGQ 497

  Fly   479 WNGMLREIIDSRADMGITDLTMTSERESGVDFTIPFMSLGIGILFRKPMKEPPKLFSFMSPFSGE 543
            ||||:||:||.:||:.:..|.:|..||..:||:.|||:|||.||:|||....|.:|||::|.|.:
  Rat   498 WNGMVRELIDHKADLAVAPLAITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPD 562

  Fly   544 VWLWLGLAYMGVSISMFVLGRLSPAEWDNPYPCIEEPTELENQFSFANCLWFSIGALLQQGSELA 608
            :|:::.||.:|||..:||:.|.||.||.||:||..:...:||.|:..|..||.:|||::|||||.
  Rat   563 IWMYVLLACLGVSCVLFVIARFSPYEWYNPHPCNPDSDVVENNFTLLNSFWFGVGALMRQGSELM 627

  Fly   609 PKAYSTRAVAASWWFFTLILVSSYTANLAAFLTVESLVTPINDADDLSKNKGGVNYGAKIGGATF 673
            |||.|||.|...|||||||::||||||||||||||.:.:||:.||||:| :..:.|||...|||.
  Rat   628 PKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAK-QTKIEYGAVEDGATM 691

  Fly   674 NFFKESNYPTYQRMYEFMRDNPQ-YMTNTNQEGVDRVENSNYAFLMESTTIEYITERRCTLTQVG 737
            .|||:|...||.:|:.||....| .:..:|:||:.||..|:|||||||||||::|:|.|.|||:|
  Rat   692 TFFKKSKISTYDKMWAFMSSRRQSVLVKSNEEGIQRVLTSDYAFLMESTTIEFVTQRNCNLTQIG 756

  Fly   738 ALLDEKGYGIAMRKNWPYRDTLSQAVLEMQEQGLLTKMKTKWWQEKRGGGACSDADEDSGAVALE 802
            .|:|.||||:......||||.::.|:|::||:|.|..||.|||   ||.| |.: :|...|.||.
  Rat   757 GLIDSKGYGVGTPMGSPYRDKITIAILQLQEEGKLHMMKEKWW---RGNG-CPE-EESKEASALG 816

  Fly   803 ISNLGGVFLVMGVGSFFGIFVSLLEMVLGVKERSDENQVSFKTELLDEIRFILQCSGNTK 862
            :.|:||:|:|:..|....:||::.|.:...|:.:...:.||.:.:::|:|..|:|....|
  Rat   817 VQNIGGIFIVLAAGLVLSVFVAVGEFLYKSKKNAQLEKRSFCSAMVEELRMSLKCQRRLK 876

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.