Protein Alignment Grik and Ir93a

DIOPT Version :9

• Sequence 1: NP_001262788.1
• Gene: Grik / 42476
• FlyBaseID: FBgn0038840
• Length: 907
• Species: Drosophila melanogaster
• Sequence 2: NP_650924.3
• Gene: Ir93a / 42471
• FlyBaseID: FBgn0259215
• Length: 868
• Species: Drosophila melanogaster
• Alignment Length: 952
• Identity: 194/952 - (20%)
• Similarity: 356/952 - (37%)
• Gaps: 250/952 - (26%)

  Fly     6 MISTEASFPLGFILTSLLLAFPGCRGERTNVGLVYENTDPDLEKIFHLAISKANEENEDLQLHGV 70
            ::.|||:....|:..:..||........|..|   ||.....|||....|      .|:|:..|:
  Fly    23 LVPTEANDFSSFLSANASLAVVVDHEYMTVHG---ENILAHFEKILSDVI------RENLRNGGI 78

  Fly    71 SVSIEPGNSFETSKKL--------C-------KMLRQNLVAVFGPTSNLAARHAMSICDAKELPF 120
            :|.....|:....|..        |       |..::..:.:...|.:...|  :.:..|..:|.
  Fly    79 NVKYFSWNAVRLKKDFLAAITVTDCENTWNFYKNTQETSILLIAITDSDCPR--LPLNRALMVPI 141

  Fly   121 LDTRWDFGAQLPTINLHPHPATLGVALRDMVVALGWESF------TIIYESGEYLPT-VRELLQM 178
            ::.    |.:.|.:.|......:          |.|::.      ||:.|:...:.: |.|.:..
  Fly   142 VEN----GDEFPQLILDAKVQQI----------LNWKTAVVFVDQTILEENALLVKSIVHESITN 192

  Fly   179 YGTAGPTVTVRRYELD--LNGNYRNVLRRIRNADDFSFVVVGSMATLPEFFKQAQQVGLVTSDYR 241
            :.|   .:::..||::  |.|..:.|..| :....|:          |:..::.:|..||.|.:.
  Fly   193 HIT---PISLILYEINDSLRGQQKRVALR-QALSQFA----------PKKHEEMRQQFLVISAFH 243

  Fly   242 ------------YIIGN------LDWHTMDLEPYQHAGTNITGLRLVSPDSEQVQEVAKALYESE 288
                        :.:||      ||....|.:    |||       |:.:.::...:|.||.|::
  Fly   244 EDIIEIAETLNMFHVGNQWMIFVLDMVARDFD----AGT-------VTINLDEGANIAFALNETD 297

  Fly   289 EPFQ-NVSCPLTN-SMALVYDGVQLLAE---TYKHVNFRPVALSCNDDSAW--------DKGYTL 340
            ...| :::|.::. |:|||....::..|   .|..::          |..|        :|...:
  Fly   298 PNCQDSLNCTISEISLALVNAISKITVEEESIYGEIS----------DEEWEAIRFTKQEKQAEI 352

  Fly   341 VNYMKSLTLNGLTGPIRFDYEGLRTDFKLEV-----IELAV------------SGMQK------- 381
            :.|||               |.|:|:.|...     :|.|:            |..|:
  Fly   353 LEYMK---------------EFLKTNAKCSSCARWRVETAITWGKSQENRKFRSTPQRDAKNRNF 402

  Fly   382 ----IGQWSGEDGFQENRPAPAHSLEPDMRSLVNKSFVVITAISEPYGMLKETSEKLEGNDQFEG 442
                ||.|:...||.....|..| :|...|   |.:..::|..:.|:.:|.:.|..:  ..:.:|
  Fly   403 EFINIGYWTPVLGFVCQELAFPH-IEHHFR---NITMDILTVHNPPWQILTKNSNGV--IVEHKG 461

  Fly   443 FGIELIDELSKKLGFSY------TWRLQEDN---KYGGIDPKTGEWNGMLREIIDS---RADMGI 495
            ..:|::.|||:.|.|||      .|: :||:   ..||.:..         |::.|   |....:
  Fly   462 IVMEIVKELSRALNFSYYLHEASAWK-EEDSLSTSAGGNESD---------ELVGSMTFRIPYRV 516

  Fly   496 TDL-------------TMTSERESGVDFTIPFMSLGIGILFRKPMKEPPKLFSFMSPFSGEVWLW 547
            .::             |:....:...::|.|........:.||| .|..:::.|.:||:.|.|..
  Fly   517 VEMVQGNQFFIAAVAATVEDPDQKPFNYTQPISVQKYSFITRKP-DEVSRIYLFTAPFTVETWFC 580

  Fly   548 LGLAYMGVSI----SMFVLGRLSPAEWDNPYPCIEEPTELENQFSFANCLWFSIGALLQQGSELA 608
            |    ||:.:    :::.:.||:|.          :...:....:..:|.|:..|||||||....
  Fly   581 L----MGIILLTAPTLYAINRLAPL----------KEMRIVGLSTVKSCFWYIFGALLQQGGMYL 631

  Fly   609 PKAYSTRAVAASWWFFTLILVSSYTANLAAFLTVESLVTPINDADDLSKNKGGVNYGAKIGGATF 673
            |.|.|.|.|...||...::||::|..||.||||.......::..:.|..:|..|.||.:.|
  Fly   632 PTADSGRLVVGFWWIVVIVLVTTYCGNLVAFLTFPKFQPGVDYLNQLEDHKDIVQYGLRNG---- 692

  Fly   674 NFFKESNYPTYQRMYEFMRDNPQYMTNTNQEGVDRVENSNYAFLMESTTIEYIT------ERRCT 732
            .||:.....|.:..::...:..:...:..:|.::.|:......:.....::.|.      |:.|.
  Fly   693 TFFERYVQSTTREDFKHYLERAKIYGSAQEEDIEAVKRGERINIDWRINLQLIVQRHFEREKECH 757

  Fly   733 LTQVG--ALLDEKGYGIAM--RKNWPYRDTLSQAVLEMQEQGLLTKMKTKWWQEKR--GGGACS- 790
            .. :|  :.:||:   |||  .....|...:::.:..|...|.:.:     |.:..  ..|.|:
  Fly   758 FA-LGRESFVDEQ---IAMIVPAQSAYLHLVNRHIKSMFRMGFIER-----WHQMNLPSAGKCNG 813

  Fly   791 -DADEDSGAVALEISNLGGVFLVMGVGSFFGIFVSLLEMVLG 831
             .|........:.:.::.|.|||:.:|     |...|.:|.|
  Fly   814 KSAQRQVTNHKVNMDDMQGCFLVLLLG-----FTLALLIVCG 850

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grik	NP_001262788.1	PBP1_iGluR_Kainate	37..391	CDD:107377	80/436 (18%)
		ANF_receptor	53..374	CDD:279440	67/380 (18%)
		Periplasmic_Binding_Protein_Type_2	411..781	CDD:304360	88/408 (22%)
		Lig_chan	543..816	CDD:278489	64/290 (22%)
Ir93a	NP_650924.3	Periplasmic_Binding_Protein_Type_2	429..>697	CDD:328725	74/301 (25%)
		Lig_chan	576..836	CDD:306551	62/286 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462814
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940