DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Grik and Ir92a

DIOPT Version :9

Sequence 1:	NP_001262788.1	Gene:	Grik / 42476	FlyBaseID:	FBgn0038840	Length:	907	Species:	Drosophila melanogaster
Sequence 2:	NP_001097845.2	Gene:	Ir92a / 42415	FlyBaseID:	FBgn0038789	Length:	678	Species:	Drosophila melanogaster

Alignment Length:	422	Identity:	82/422 - (19%)
Similarity:	149/422 - (35%)	Gaps:	118/422 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   466 DNKYGGI-DPKTGEWNGMLREIIDSRADM----------GITDLTMTSERESGVDFTIPFMSLGI 519
            || :||| |.::.:  |||.:|.:.|.:|          |||:.:.|..|.|            :
  Fly   311 DN-WGGIYDNESSD--GMLGDIYEQRVEMAIGCIYNWYDGITETSHTIARSS------------V 360

  Fly   520 GILFRKPMKEPPKLFSFMSPFSGEVWLWL-------------------GLAYMGVSISMFVLGRL 565
            .||...|...|....:.| ||:...||.|                   .|.|.|..:......:|
  Fly   361 TILGPAPAPLPSWRTNIM-PFNNRAWLVLISTLVICGTFLYFMKYVSYRLRYSGTQVKFHHSRKL 424

  Fly   566 SPAEWDNPYPCIEEPTELENQFSFANCLWFSIGALLQQGSELAPKAYSTRAVAASWWFFTLILVS 630
            ..:..|.....|::|:.   ..||               ...||:.:....:.|     |:.|.:
  Fly   425 EKSMLDIFALFIQQPSA---PLSF---------------DRFAPRFFLATILCA-----TITLEN 466

  Fly   631 SYTANLAAFLTVESLVTPINDADDLSKNKGGVNYGAKIGGATF---NFFKESNYPTYQRM----- 687
            .|:..|.:.||......|::..:..:::      |.|....:.   :..:.|:..|.|.:
  Fly   467 IYSGQLKSMLTFPFYSAPVDTIEKWAQS------GWKWSAPSIIWVHTVQSSDLETEQILARNFE 525

  Fly   688 ---YEFMRDNPQYMTNTNQEGVDRVENSNYAFLMESTTIEYIT----ERRCTLTQVGALLDEKGY 745
               |.:: .|..:|.|.. .|::|:.:.:.      :..:|::    |.|..|..  .|..:...
  Fly   526 VHDYSYL-SNVSFMPNYG-FGIERLSSGSL------SVGDYVSTEALENRIVLHD--DLYFDYTR 580

  Fly   746 GIAMRKNWPYRDTLSQAVLEMQEQGL------------LTKMKTKWWQEKRGGGACSDADEDSGA 798
            .:::| .|.....|::.:...||.||            :.|.|.:...:...|.....|.:
  Fly   581 AVSIR-GWILMPELNKHIRTCQETGLYFHWELEFIDKYMDKKKQEVLMDLANGHKVKGAPQ---- 640

  Fly   799 VALEISNLGGVFLVMGVGSFFGIFVSLLEMVL 830
             ||::.|:.|...|:..|..|.....:.|:::
  Fly   641 -ALDVRNIAGALFVLAFGVAFAGCALVAELLI 671

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Grik	NP_001262788.1	PBP1_iGluR_Kainate	37..391	CDD:107377
		ANF_receptor	53..374	CDD:279440
		Periplasmic_Binding_Protein_Type_2	411..781	CDD:304360	72/371 (19%)
		Lig_chan	543..816	CDD:278489	54/318 (17%)
Ir92a	NP_001097845.2	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462839
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840