Protein Alignment Grik and Ir75d

DIOPT Version :9

• Sequence 1: NP_001262788.1
• Gene: Grik / 42476
• FlyBaseID: FBgn0038840
• Length: 907
• Species: Drosophila melanogaster
• Sequence 2: NP_649074.2
• Gene: Ir75d / 40065
• FlyBaseID: FBgn0036829
• Length: 675
• Species: Drosophila melanogaster
• Alignment Length: 619
• Identity: 123/619 - (19%)
• Similarity: 227/619 - (36%)
• Gaps: 151/619 - (24%)

  Fly   238 SDYRYIIGNLDWHTMDLEPYQHAGTNITGLR----LVSPDSEQVQEVAKALYESEEPFQNVSCPL 298
            |::.|...|..|..:..:|     .:|..|.    .:.||||     .:.|:  .|...|.||.
  Fly   162 SEHNYFTTNRFWLLLTEDP-----GDIDLLEDPEIFIPPDSE-----LRVLH--YENVGNFSCS- 213

  Fly   299 TNSMALVYDGVQLLAETYKHVNFRPVALSCNDDSAWDKGYTLVNYMKSLTLNGLTGPIRFDYEGL 363
                         |.:.||...::|:.            .|||.:                  .:
  Fly   214 -------------LIDLYKVAAWKPLK------------RTLVGH------------------NI 235

  Fly   364 RTDFKLEVIELAVSGMQKIGQWSGEDGFQENRPAPAHSLEPDMRSLVNKSFVVITAISEPYGMLK 428
            |..      ...:..:|..|.              |.:...|:..:|..|.:|| |..:.:..::
  Fly   236 RNS------RHVIHALQHFGS--------------AITYRQDLEGIVFNSAIVI-AFPDLFTNIE 279

  Fly   429 ETSEKLEGNDQFEGFGIELIDELSKKLGFSYTWRLQEDNKYGGIDPKTGEWNGMLREIIDSRADM 493
            :.|  |...|........|:.||:.:|..||  ...:...||...| .|.::|::........|:
  Fly   280 DLS--LRHIDTISKVNHRLMLELANRLNMSY--NTYQTVNYGWRQP-NGSFDGLMGRFQRYELDL 339

  Fly   494 GITDLTMTSERESGVDFTIPFMSLGIGILFRK-PMKEPPKLFSFMSPFSGEVWLWLGLAYMGVSI 557
            ....:.|..:|.:.|||......:..||:||: |:.....:|:.  ||..:||:.:.:..:..::
  Fly   340 AQLAIFMRLDRIALVDFVAETYRVRAGIMFRQPPLSAVANIFAM--PFENDVWVSILMLLIITTV 402

  Fly   558 SMFVLGRLSPAEWDNPYPCIEEPTELENQFSFANCLWFSIGALLQQGSELAPKAYSTRAVAASWW 622
            .:.:....||...|..|            ....|.:|   ||:.|||..:..:..|.|.:..:.:
  Fly   403 VLVLELFFSPHNHDMSY------------MDTLNFVW---GAMCQQGFYVEVRNRSARIIVFTTF 452

  Fly   623 FFTLILVSSYTANLAAFLTVESLVTPINDADDLSKNKGGVNYGAKIG--GATFN--FFKESNYPT 683
            ...|.|.:|::||:.|.|  :|....|....||.::.      .:||  ...:|  :|.||..|.
  Fly   453 VAALFLFTSFSANIVALL--QSPSDAIQSLSDLGQSP------LEIGVQDTQYNKIYFTESTDPV 509

  Fly   684 YQRMYE----------FMRDNPQYMTNTNQEGVDRVENSNYAFLMESTTIEYITERRCTLTQVGA 738
            .:.:|.          :||  |..       |::::....:|:.:|......|.....:..:...
  Fly   510 TKNLYHKKIASKGENIYMR--PLL-------GMEKMRTGLFAYQVELQAGYQIVSDTFSEPEKCG 565

  Fly   739 LLDEKGYGIAM-----RKNWPYRDTLSQAVLEMQEQGLLTKMKTKWWQEK---RGGGACSDADED 795
            |::.:.:.:.|     |||:||::.:.:.:...:|..|:.:.:.||..:|   .||        .
  Fly   566 LMELEPFQLPMLAIPTRKNFPYKELIRRQLRWQREVSLVNREERKWIPQKPKCEGG--------V 622

  Fly   796 SGAVALEISNLGGVFLVMGVGSFFGIFVSLLEMV 829
            .|.|::.|:.......:.|.|:.....:.|.|.:
  Fly   623 GGFVSIGITECRYALGIFGCGAAVSFVLFLFEFI 656

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grik	NP_001262788.1	PBP1_iGluR_Kainate	37..391	CDD:107377	26/156 (17%)
		ANF_receptor	53..374	CDD:279440	24/139 (17%)
		Periplasmic_Binding_Protein_Type_2	411..781	CDD:304360	84/389 (22%)
		Lig_chan	543..816	CDD:278489	59/294 (20%)
Ir75d	NP_649074.2	Periplasmic_Binding_Protein_Type_2	299..>483	CDD:304360	48/205 (23%)
		Lig_chan	388..644	CDD:278489	59/295 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462820
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940