Protein Alignment Grik and Ir60a

DIOPT Version :9

• Sequence 1: NP_001262788.1
• Gene: Grik / 42476
• FlyBaseID: FBgn0038840
• Length: 907
• Species: Drosophila melanogaster
• Sequence 2: NP_611901.1
• Gene: Ir60a / 37881
• FlyBaseID: FBgn0034994
• Length: 716
• Species: Drosophila melanogaster
• Alignment Length: 679
• Identity: 120/679 - (17%)
• Similarity: 221/679 - (32%)
• Gaps: 219/679 - (32%)

  Fly   264 ITGLRLVSPDSEQVQE-VAKALYES---------EEPFQ-------NVS--------CPLTNSMA 303
            :....|.|| ::|:|| .:|.:.|:         ||.||       |::        ..|.::..
  Fly    81 VHAFHLSSP-ADQIQEGFSKLINEAVTNPGPPDREELFQMRVASDYNITNGTEDKGELILADNYV 144

  Fly   304 LVYDGVQLLAETYKH--VNFRPVALSCNDDSAWDKGYTLVNYMKSLTLN----GLTGPIRFD--- 359
            :|.|.|..|.|..|.  |..|          :|:.|...:....:.|..    |:...|..|
  Fly   145 IVVDSVDRLKELMKKKIVEMR----------SWNPGARFLVLFHNATCRNRPLGVASNIFKDLME 199

  Fly   360 ----------YEGLRTDFKLEV------IELAVSGMQKIGQWSGEDGFQENRPAPAHSLEPDMRS 408
                      |.....::.|.|      :...:..:|.:||......:..|....|     .|:.
  Fly   200 MFYVHRVALLYANSTMNYNLLVNDYYSNVNCRILNVQSVGQCHDGKLYPNNAVVKA-----SMQD 259

  Fly   409 LV------NKSFVVITAISEPYGMLKETSEKLEGNDQFEGFGIELIDELSKKLGF--SYTWRLQE 465
            .|      |.:|...::||.|:         :|. |...|..:.::..:..:|.|  :.|..|:.
  Fly   260 YVSGFSPRNCTFFACSSISAPF---------VEA-DCILGLEMRILGFMKNRLKFDVNQTCSLES 314

  Fly   466 DNKYGGIDPKTGEWNGMLREIIDSRADM---GITDLTMTSERESGVDFTI--------------P 513
            ..:..|    ...|.|:|.::.::..|.   |.......::...|.|..:              |
  Fly   315 RGEMDG----PANWTGLLGKVQNNECDFVFGGYYPDNEVADHFWGSDTYLQDAHTWYIKMADRRP 375

  Fly   514 FMSLGIGILFRKPMKEPPKLFSFMSPFSGEVWLWLGLAYMGVSISMFVLGRLSPAEWDNPYPCIE 578
            .....:||.                    |.:.|:|...:.:...:|         |......:.
  Fly   376 AWQALVGIF--------------------EAYTWIGFILILIISWLF---------WFTLVMILP 411

  Fly   579 EPTELENQFSFA--NCLWFSIGALLQQGSELAPKAYSTRAVAASWWFFTLILVSSYTANLAAFLT 641
            || :...|.|..  |.|..:|...:|:    .|...:||....:...:.|.:|::||:.:.|
  Fly   412 EP-KYYQQLSLTAINALAVTISIAVQE----RPICETTRLFFMALTLYGLNVVATYTSKMIA--- 468

  Fly   642 VESLVTP--INDADDLSKNKGGVNYGAKIGGATFNFFKESNYPTYQRMYEFMRDNPQYMTNTNQE 704
              :...|  ::..|:|::   .|..|...||                 :|..||   :..|.:..
  Fly   469 --TFQDPGYLHQLDELTE---VVAAGIPFGG-----------------HEESRD---WFENDDDM 508

  Fly   705 GVDRVENSNYAFLMESTTIEYIT-ERRCTL-----TQVGALLD----------EKGYGIAMRKNW 753
            .:....|.:..|:.:|..:|.:. .:||.|     |....|.|          .....:.|:..:
  Fly   509 WIFNGYNISPEFIPQSKNLEAVKWGQRCILSNRMYTMQSPLADVIYAFPNNVFSSPVQMIMKAGF 573

  Fly   754 PYRDTLSQAVLEMQEQGLLTKMKTKWWQEKRGGGACSDAD-----------------EDSGAVAL 801
            |:...::..:..|::.|:..|:               |||                 ....|:.|
  Fly   574 PFLFEMNSIIRLMRDVGIFQKI---------------DADFRYNNTYLNRINKMRPQFPETAIVL 623

  Fly   802 EISNLGGVFLVMGVGSFFGIFVSLLEMVL 830
            ...:|.|.|.::.|||.:.....:.|:::
  Fly   624 TTEHLKGPFFILVVGSCWAALTFIGELII 652

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grik	NP_001262788.1	PBP1_iGluR_Kainate	37..391	CDD:107377	34/176 (19%)
		ANF_receptor	53..374	CDD:279440	31/159 (19%)
		Periplasmic_Binding_Protein_Type_2	411..781	CDD:304360	70/408 (17%)
		Lig_chan	543..816	CDD:278489	55/309 (18%)
Ir60a	NP_611901.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462828
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840