Protein Alignment Grik and LOC3289757

DIOPT Version :10

• Sequence 1: NP_001262788.1
• Gene: Grik / 42476
• FlyBaseID: FBgn0038840
• Length: 907
• Species: Drosophila melanogaster
• Sequence 2: XP_061498361.1
• Gene: LOC3289757 / 3289757
• VectorBaseID: AGAMI1_010049
• Length: 949
• Species: Anopheles gambiae
• Alignment Length: 905
• Identity: 462/905 - (51%)
• Similarity: 636/905 - (70%)
• Gaps: 41/905 - (4%)

  Fly    32 ERTNVGLVYENTDPDLEKIFHLAISKANEEN---EDLQLHGVSVSIEPGNSFETSKKLCKMLRQN 93
            |...:|.:::....|:|..|..|:...|.|.   .:.||...:|.::.|:.|:.|||||::|:..
Mosquito    37 EHIKIGGLFDGATEDVELAFQYAVEAVNNEKLSYSNYQLEAQAVQVKYGDQFDASKKLCRLLKTG 101

  Fly    94 LVAVFGPTSNLAARHAMSICDAKELPFLDTRWDFGAQLPTINLHPHPATLGVALRDMVVALGWES 158
            :..:|||:|..:|.|..|:||.||:|.::||||...:|||:||||||..:|....|:|||..|:|
Mosquito   102 VAGIFGPSSPKSALHVQSVCDEKEMPHIETRWDAYTKLPTLNLHPHPHIMGRVFLDLVVAFEWKS 166

  Fly   159 FTIIYESGEYLPTVRELLQMYGTAGPTVTVRRYELDLNGNYRNVLRRIRNADDFSFVVVGSMATL 223
            ||::||||.:||.:.:||:||...|.|||||:.:|.||||||.||||::.::|...::..|:.::
Mosquito   167 FTVLYESGPWLPGIADLLKMYDPKGYTVTVRQLDLGLNGNYRAVLRRVKLSEDKRIILACSIDSM 231

  Fly   224 PEFFKQAQQVGLVTSDYRYIIGNLDWHTMDLEPYQHAGTNITGLRLVSPDSEQVQEVAKALYESE 288
            ||..:|||||||:|..::.|:.:||.||:||||||::||||||:||:.|:.:::::||..|..|:
Mosquito   232 PEVLRQAQQVGLLTDHHQIIVTSLDLHTIDLEPYQYSGTNITGVRLIDPEEDKIRQVADFLNASQ 296

  Fly   289 -----------EPFQNVSCPLTNSMALVYDGVQLLAETYKHV-------NFRPVALSCNDDSAWD 335
                       .|     ..:....||:||.|.|.||..||:       ...|:||.|:|.:.|.
Mosquito   297 IAKTLELQDGLNP-----AKMRVETALMYDAVLLFAEALKHLIGSEPAHLLEPIALRCDDTATWK 356

  Fly   336 KGYTLVNYMKSLTLNGLTGPIRFDYEGLRTDFKLEVIELAVSGMQKIGQWSGEDGFQENRPAPAH 400
            .||:::|||||.|::|||..||||::|.|:||.|::|||..:|::|:|.|:..:|....|.....
Mosquito   357 NGYSVINYMKSSTIHGLTRSIRFDHQGHRSDFLLDIIELGPAGLEKVGVWNSTEGLNFTRKKEQT 421

  Fly   401 SLEPDMRSLVNKSFVVITAISEPYGMLKETSEKLEGNDQFEGFGIELIDELSKKLGFSYTWRLQE 465
            .|..|..:|.|::|:|:||||.||||||::..||.||::||||||:||.|||..|||:||:.|||
Mosquito   422 LLAFDDGTLQNRTFLVLTAISPPYGMLKDSPVKLTGNERFEGFGIDLIHELSLMLGFNYTFILQE 486

  Fly   466 DNKYGGIDPKTGEWNGMLREIIDSRADMGITDLTMTSERESGVDFTIPFMSLGIGILFRKPMKEP 530
            |..||.::..|.:||||:.|:::.|||:.|||||:||:|||.||||:|||:|||.||:|||.|||
Mosquito   487 DGVYGSLNRDTKKWNGMVLELLEWRADLAITDLTITSDRESAVDFTMPFMNLGISILYRKPTKEP 551

  Fly   531 PKLFSFMSPFSGEVWLWLGLAYMGVSISMFVLGRLSPAEWDNPYPCIEEPTELENQFSFANCLWF 595
            |.|||||||||.:|||:||.|||.||:|:|:|||:||.||||||||||||.||||||||:|.:||
Mosquito   552 PSLFSFMSPFSKQVWLYLGGAYMMVSMSLFILGRISPKEWDNPYPCIEEPEELENQFSFSNSMWF 616

  Fly   596 SIGALLQQGSELAPKAYSTRAVAASWWFFTLILVSSYTANLAAFLTVESLVTPINDADDLSKNKG 660
            :||||||||||:||||.:|||||:.|||||||:|||||||||||||||.:|:||::|:||:...|
Mosquito   617 TIGALLQQGSEIAPKAPATRAVASIWWFFTLIMVSSYTANLAAFLTVEQVVSPISNAEDLAAAGG 681

  Fly   661 GVNYGAKIGGATFNFFKESNYPTYQRMYEFMRDNPQYMTNTNQEGVDRVENSNYAFLMESTTIEY 725
            .:.||||..|:|.:|||::.|.||.:||::|..|.:.:|::|.||:.||:..|||||||||:|||
Mosquito   682 TIKYGAKRDGSTISFFKDAEYGTYAKMYQYMMANQELLTSSNPEGLQRVKTENYAFLMESTSIEY 746

  Fly   726 ITERRCTLTQVGALLDEKGYGIAMRKNWPYRDTLSQAVLEMQEQGLLTKMKTKWWQEKRGGGACS 790
            |.||.|.:||:|.|||:||||||||||.|||..||:|||.:||||:||.:|.|||:|||||||||
Mosquito   747 IVERECDVTQIGGLLDDKGYGIAMRKNSPYRSALSEAVLRLQEQGVLTSLKRKWWKEKRGGGACS 811

  Fly   791 DADEDSGAVALEISNLGGVFLVMGVGSFFGIFVSLLEMVLGVKERSDENQVSFKTELLDEIRFIL 855
            .:..|.||..|::.|:||||.|:.||..|.......|:...:..|:..::|.|:.||:.|:||:.
Mosquito   812 QSTSDDGAEELDMDNVGGVFFVLFVGCSFASLFGCCELFFVIAHRARRHKVPFREELMAELRFVA 876

  Fly   856 QCSGNTKAVKYPKNSSRS----------NASSKSK----GSSMSVDSLPEDTSEADASGK 901
            :|.||||.|::.|:||.|          :::|.||    |:.|. |.||.........||
Mosquito   877 KCHGNTKPVRHRKSSSASGENSLELDVEDSTSSSKQDISGNGMG-DRLPTGNQRRQNGGK 935

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grik	NP_001262788.1	PBP1_iGluR_Kainate	35..395	CDD:380605	160/380 (42%)
		Periplasmic_Binding_Protein_Type_2	411..781	CDD:473866	245/369 (66%)
LOC3289757	XP_061498361.1	None