Protein Alignment Grik and Ir7c

DIOPT Version :10

• Sequence 1: NP_001262788.1
• Gene: Grik / 42476
• FlyBaseID: FBgn0038840
• Length: 907
• Species: Drosophila melanogaster
• Sequence 2: NP_572411.1
• Gene: Ir7c / 31692
• FlyBaseID: FBgn0029966
• Length: 625
• Species: Drosophila melanogaster
• Alignment Length: 491
• Identity: 99/491 - (20%)
• Similarity: 167/491 - (34%)
• Gaps: 129/491 - (26%)

  Fly   389 DGFQENRPAPAHSLEPDMRSLVNK---SFVVITAISEPYGMLKETSEKLEGNDQFEGFGIELIDE 450
            :||...:|     |.|  |.|.|.   ..||.|....|| ::.|...|..|.....|....:...
  Fly   195 NGFGLTKP-----LFP--RKLTNMHGCEMVVATFEHRPY-VIIEDDPKTPGGRSIHGIEGLIFRS 251

  Fly   451 LSKKLGFSYTWRLQEDNKYGGIDPKTGEWNGMLREIIDSRADMGI---------TDLTMTSERES 506
            |::::.|:.....|:|...|.|.| .|.:.|:|:.::|...::..         :||.:.|...:
  Fly   252 LAERMNFTIKLVEQKDKNRGEILP-DGNFTGILKMMVDGEVNLTFVCFMYSKARSDLMLPSTSYT 315

  Fly   507 GVDFTIPFMSLG----IGILFRKPMKEPPKLFSFMSPFSGEVW--LWLGLAYMGVSISM------ 559
            .....:...|.|    :|.|.|              ||...:|  :.:.|.:..|.|.:
  Fly   316 SFPIVLVVPSGGSISPMGRLTR--------------PFRYIIWSCILVSLIFGFVLICLLKITAL 366

  Fly   560 -----FVLGRLSPAEWDNPYPCIEEPTELENQFSFANCLWFS-IGALLQQGSELAPKAYSTRAVA 618
                 .||||                   .|:..|.. :|.| :|.|....    |:....|.:.
  Fly   367 PGLRNLVLGR-------------------RNRLPFMG-MWASLLGGLALYN----PQRNFARYIL 407

  Fly   619 ASWWFFTLILVSSYTANLAAFLTVESLVTPINDADD-LSKNKGGVNYGAKIGGATFNFFKESNYP 682
            ..|...||||.::||..|...|....:.:||....: |:|     :|..:|..|....||:|
  Fly   408 VMWLLQTLILRAAYTGQLYLLLQDVEMRSPIKSLSEVLAK-----DYEFRILPALRTIFKDS--- 464

  Fly   683 TYQRMYEFMRDNPQYMTNTNQEGVDRVENSNYAF-----------LMESTTIEY---ITERRCTL 733
                           |..||...|..:|.|.|..           |::.|..::   ....:..|
  Fly   465 ---------------MPTTNFHAVLSLEESLYRLRDEDDPGITVALLQPTVNQFDFRSGPNKRHL 514

  Fly   734 TQVGALLDEKGYGIAMRKNWPYRDTLSQAVLEMQEQGLLTKMKTKWWQ-----EKRGGGACSDAD 793
            |.:...|........||.:..::..:.:.::.|...|::.:.:..:..     .||
  Fly   515 TVLPDPLMTAPLTFYMRPHSYFKRRIDRLIMAMMSSGIVARYRKMYMDRIKRVSKR--------- 570

  Fly   794 EDSGAVALEISNLGGVFLVMGVGSFFGIFVSLLEMV 829
            .:.....|.|..|.|:|:.........:.|.:||::
  Fly   571 RNLEPKPLSIWRLSGIFVCCAGLYLVALIVFILEIL 606

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grik	NP_001262788.1	PBP1_iGluR_Kainate	35..395	CDD:380605	2/5 (40%)
		Periplasmic_Binding_Protein_Type_2	411..781	CDD:473866	82/414 (20%)
Ir7c	NP_572411.1	Lig_chan-Glu_bd	225..287	CDD:214911	16/63 (25%)
		Lig_chan	343..592	CDD:459656	58/304 (19%)