Protein Alignment Grik and glr-7

DIOPT Version :9

• Sequence 1: NP_001262788.1
• Gene: Grik / 42476
• FlyBaseID: FBgn0038840
• Length: 907
• Species: Drosophila melanogaster
• Sequence 2: NP_001337310.1
• Gene: glr-7 / 180547
• WormBaseID: WBGene00001618
• Length: 885
• Species: Caenorhabditis elegans
• Alignment Length: 920
• Identity: 233/920 - (25%)
• Similarity: 395/920 - (42%)
• Gaps: 201/920 - (21%)

  Fly    65 LQLHGVSVSIEPGNSFETSKKLCKMLRQNLVA-VFG-----PTSNL-----------AARHAMSI 112
            |..:|.||......|: |:..|..::.||::. :|.     |.|.:           |.|.|.|:
 Worm    74 LNFNGTSVPTISSPSY-TTMVLSTLVFQNVITDIFADLNITPNSTVLYDNMYPPDFTAWRDAFSV 137

  Fly   113 CDA-KELPFLDTRWDFGAQLPTINLHPHPATLGVALRDMVVALGWESFTIIYESGEYLPTVRELL 176
            ... :.:|...|.....||:..:.:....:.:.||..:.|     |.||:  |:.:::..
 Worm   138 LPGIRFVPMETTVLRMRAQITQLRMASINSLILVAKTENV-----ERFTL--EAADFIEQ----- 190

  Fly   177 QMYGTAGPTVTVRRYELD---------LNGNYRNVLRRIRNADDFSFVVVGSMATLPEFFKQAQQ 232
            :::.|...|..:..::.|         |.......|..||:.||:.|               ..:
 Worm   191 RVFNTYVLTKDITAFKCDSCESAFMFWLRPFPVGKLMEIRDLDDYLF---------------RNE 240

  Fly   233 VGLVTSDYRYIIGNLDWHTMDLEPYQHAGTNITGLRLVSPDSEQVQEVAKALYESEEPFQNVSCP 297
            :||   :..|.|..  |.::::..|.    |:.|...         |..:.:..:.:.....:|.
 Worm   241 IGL---ELDYSING--WDSLNVAFYM----NVMGYAF---------ETIRTMNATFDVLPTFTCQ 287

  Fly   298 LTNSMALVYDGVQLLAETYKHVNFRPVALSCNDDSAWDKGYTLVNYMKSLTLNGLTGPIRFDYEG 362
            ...|            |.......|.:.|   :|.|.:.|    ||.::               |
 Worm   288 TGPS------------EPNITTTVRDIIL---NDPAHEYG----NYTEA---------------G 318

  Fly   363 LRTDFKLEVIELAVSGM------------QKIGQWSGEDGFQENRPAPAHS-----LEPDMRSLV 410
            |...|  :.:|:.:..:            :::|.||         |....|     |:.|:|:|
 Worm   319 LNMFF--QDVEVRIYKIDRDRDHEDALFNKEVGVWS---------PISKLSVMYGTLQVDVRNL- 371

  Fly   411 NKSFVVITAISEPYGMLKETSEKLEGNDQFEGFGIELIDELSKKLGFSYTWRLQEDNKYGGIDPK 475
             ..|.|:|.|..|:  ::.|.:.   :..:||:.|:||:.:..::.|:||....||..:|.:| .
 Worm   372 -NIFRVVTLIQPPF--VQRTGDP---DTPYEGYCIDLINMIQVEVNFTYTIYEVEDGSFGTMD-D 429

  Fly   476 TGEWNGMLREIIDSRADMGITDLTMTSERESGVDFTIPFMSL-GIGILFRKPMKEPPKLFSFMSP 539
            .|.|||::..::...||:.:..|::.:|||:.||||:|:..| |..||.:|...| ..||.||..
 Worm   430 NGNWNGLIGALVSGSADIALAPLSVMAERENDVDFTVPYYDLVGTTILMKKADVE-YSLFKFMKV 493

  Fly   540 FSGEVWLWLGLAYMGVSISMFVLGRLSPAEWDNPYPCIEEPTELENQFSFANCLWFSIGALLQQG 604
            ....|||.:..||:..||.:::..|.||..:.|.....:...| :.|||...||||.:.:|..||
 Worm   494 LEWPVWLCIVAAYLFTSILLWIFDRFSPYSFTNNKERYQNDIE-KRQFSLKECLWFCMTSLTPQG 557

  Fly   605 SELAPKAYSTRAVAASWWFFTLILVSSYTANLAAFLTVESLVTPINDADDLSKN--------KGG 661
            ...|||..|.|.|||:||.|..|:::||||||||||||..|..||:..|||:|.        ||.
 Worm   558 GGEAPKNISGRLVAATWWLFGFIIIASYTANLAAFLTVSRLEQPISSLDDLAKQYKIEYAPIKGS 622

  Fly   662 VNYG-----AKIGGATFNFFKES-----------------NYPT---YQRMYEFMRDN--PQYMT 699
            .:..     |:|....:|.:||.                 :||.   :..|:.:|:::  |..|
 Worm   623 ASETYFRRMAEIEETFYNMWKEMSLNESMSPRDRAKLAVWDYPVSDKFTNMWRYMQESKLPVNM- 686

  Fly   700 NTNQEGVDRVENS--NYAFLMESTTIEYITERRCTLTQVGALLDEKGYGIAMRKNWPYRDTLSQA 762
               ...||||.||  .:||:.::|.|:|.....|.|.|||.....|.|.||::.....:|.:|.|
 Worm   687 ---DTAVDRVLNSVDGFAFIGDATEIKYAALTNCNLQQVGTEFSRKPYAIAVQSGHILKDKISSA 748

  Fly   763 VLEMQEQGLLTKMKTKWWQEKRGGGACSDADEDSGAVALEISNLGGVFLVMGVGSFFGIFVSLLE 827
            :|.:..:..|..:|.|||.:.....:|.|:.::|..::  |.|:||||:|:    ..||.:|::.
 Worm   749 ILMLLNERRLETLKEKWWTDNPNKVSCPDSSDESDGIS--IQNIGGVFIVI----LAGIALSIVT 807

  Fly   828 MVLG---VKERSDENQVSFKTEL-LDEIRFILQCSGNTKAVKY--PK--NSSRSNASSKSKGSSM 884
            :...   .|.::.:.....:.|| :.:.:.::....:|..||.  ||  |.:::|.::..:....
 Worm   808 LAFEYYYYKRKARKAAEKEQEELEMKQSQQVVPNGFHTNGVKQDAPKLTNGTKTNGNTFRRTKRS 872

  Fly   885 SVDSLPEDTS 894
            :..|..|:|:
 Worm   873 NSVSAYENTA 882

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grik	NP_001262788.1	PBP1_iGluR_Kainate	37..391	CDD:107377	63/364 (17%)
		ANF_receptor	53..374	CDD:279440	59/335 (18%)
		Periplasmic_Binding_Protein_Type_2	411..781	CDD:304360	137/407 (34%)
		Lig_chan	543..816	CDD:278489	105/309 (34%)
glr-7	NP_001337310.1	Periplasmic_Binding_Protein_Type_1	<102..>220	CDD:324556	22/129 (17%)
		PBP2_iGluR_putative	373..767	CDD:270435	137/405 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000021
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910