Protein Alignment Grik and LOC1276693

DIOPT Version :10

• Sequence 1: NP_001262788.1
• Gene: Grik / 42476
• FlyBaseID: FBgn0038840
• Length: 907
• Species: Drosophila melanogaster
• Sequence 2: XP_061500826.1
• Gene: LOC1276693 / 1276693
• VectorBaseID: AGAMI1_001614
• Length: 972
• Species: Anopheles gambiae
• Alignment Length: 972
• Identity: 300/972 - (30%)
• Similarity: 478/972 - (49%)
• Gaps: 153/972 - (15%)

  Fly     8 STEASFPLGFILTS------------LLLAFPGCR----------GERTNVGLVYENTDPDLEKI 50
            ||.|:.|.|.:..|            ||:|....:          .|:..:|.::|....:::..
Mosquito    18 STNAASPAGVVRRSKPTIMLPLAAALLLVALSHMQTPVSANAQPPTEKIPLGAIFEQGTDEIQSA 82

  Fly    51 FHLAISKAN----EENEDLQLHGVSVSIEPGNSFETSKKLCKMLRQNLVAVFGPTSNLAARHAMS 111
            |..|:...|    ....:||.: |.| |...::|:.||.:|....:.:.|:.|..|..:.....|
Mosquito    83 FKFAMLNHNLNVTARRFELQAY-VDV-INTADAFKLSKLICNQFSRGVFAMLGAVSPDSFDTLHS 145

  Fly   112 ICDAKELPFLDTRWDFGAQLPTINLHPHPATLGVALR----------DMVVALGWESFTIIYESG 166
            ..:..::||: |.|     .|...|.|....|..|:.          |.|...||:....:|:|.
Mosquito   146 YSNTFQMPFV-TPW-----FPEKVLTPSSGFLDFAISMRPDYYQAIIDTVRYYGWDRIIYMYDSH 204

  Fly   167 EYLPTVRELLQMYGTAGPTV---TVRRYELDLNGNYRNVLRRIRNADDFS-----FVVVGSMATL 223
            :.|..::::.|.......|.   ||:|.     .|..:.:..:|..::.:     .:|:.....|
Mosquito   205 DGLLRLQQIYQGLRPGNETFHVETVKRI-----ANVSDAIEFLRTIEELNRWSRKHIVLDCSTEL 264

  Fly   224 PE--FFKQAQQVGLVTSDYRYIIGNL----DWHTMDLEPYQHAGTNITGLRLVSPDSEQVQEVAK 282
            .:  .....:.:.|....|.|::..|    .|.:   |..::...||||.|:|....:.|:|...
Mosquito   265 AKDIVVSHVRDITLGKRTYHYLLSGLVMDDRWES---EVIEYGAINITGFRIVDTSKKYVKEFLD 326

  Fly   283 ALYESEEP--FQNVSCPLTNSM-ALVYDGVQLLAETYKHV------NFRPV-------------- 324
            . ::..:|  .|.....|.::. ||:||.|.:|.|.:..:      .||..
Mosquito   327 G-WKRLDPTTSQGAGKELISAQAALMYDAVFVLVEAFSKIMRKKPDQFRAYTMRNRGQPFNLPAN 390

  Fly   325 ---ALSCNDD----SAWDKGYTLVNYMKSLTLNGLTGPIRFDYEGLRTDFKLEVIELAV-SGMQK 381
               .|.||..    :.|:.|..:..|::.:.::||||.|||:.:|.|.::.|.|:|:.| |.|.|
Mosquito   391 GTRTLDCNTSKGWVTPWEHGDKISRYLRKVEISGLTGDIRFNEDGKRQNYTLHVVEMTVNSAMVK 455

  Fly   382 IGQWSGEDGFQENRPAPAHS----LEPDMRSLVNKSFVVITAISEPYGMLK--ETSEKLEGNDQF 440
            :.:||.|.|.     ||..:    |:.||....||:::|.|.|.|||.||:  |..|.||.|::|
Mosquito   456 VAEWSDEGGL-----APVVAKYTRLKTDMHYERNKTYIVTTIIEEPYIMLRQPEPGETLETNERF 515

  Fly   441 EGFGIELIDELSKKLGFSYTWRLQEDNKYGGIDPKT-GEWNGMLREIIDSRADMGITDLTMTSER 504
            ||:..:|.:.::||||.:|..|:.:|.:||..:|.. |.|:||:.|::...||..|..:|:||||
Mosquito   516 EGYCKDLAELVAKKLGINYELRIVKDGQYGSENPDVKGGWDGMVGELVRKEADFAIAPMTITSER 580

  Fly   505 ESGVDFTIPFMSLGIGILFRKPMKEPPKLFSFMSPFSGEVWLWLGLAYMGVSISMFVLGRLSPAE 569
            |..:||:.|||||||.|:.::|:|:.|.:|||::|.|.|:|:.:..:|:||||.::::.|.||.|
Mosquito   581 ERVIDFSKPFMSLGISIMIKRPVKQKPSVFSFLNPLSKEIWVCVLFSYVGVSIVLYIVSRFSPFE 645

  Fly   570 W-------DNPYPCIEEPTELENQFSFANCLWFSIGALLQQGSELAPKAYSTRAVAASWWFFTLI 627
            |       :.|...   |....|:||..|..||::||.:|||.:::|::.|.|.|.:.|||||||
Mosquito   646 WRLVNYNGEQPDAV---PQATVNEFSILNSFWFALGAFMQQGCDISPRSISGRIVGSVWWFFTLI 707

  Fly   628 LVSSYTANLAAFLTVESLVTPINDADDLSKNKGGVNYGAKIGGATFNFFKESNYPTYQRMYEFMR 692
            |:||||||||||||||.:|||||..:||: ::..|.||..|.|:|::||::|....|.||:|:|.
Mosquito   708 LISSYTANLAAFLTVERMVTPINSPEDLA-SQTEVQYGTLIHGSTWDFFRKSQISLYSRMWEYMN 771

  Fly   693 DNPQYMTNTNQEGVDRVENS--NYAFLMESTTIEYITERR-CTLTQVGALLDEKGYGIAMRKNWP 754
            ........:..||:.||..|  .||.|:||...||..||. |...:||..||.||:|||.....|
Mosquito   772 SRKHLFVKSYDEGIRRVRTSKGKYALLIESPKNEYTNEREPCDTMKVGRNLDAKGFGIATPLGSP 836

  Fly   755 YRDTLSQAVLEMQEQGLLTKMKTKWWQEKRGGGACSDAD-EDSGAVALEISNLGGVFLVMGVGSF 818
            .||.::.|||.::|.|.|||:..|||.::.   .|...| :|:....|.:||:.|:|.::..|..
Mosquito   837 LRDPINLAVLSLKENGELTKLVNKWWFDRT---ECKHYDKQDASRNELSLSNVAGIFYILIGGLL 898

  Fly   819 FGIFVSLLEMVLGVKERSDENQVSFKTELLDEIRFILQCSGNTKAVKYPKNSSRSNASSKSK 880
            ..:.|:|:|..:....|| .|::..                        .::..||::||::
Mosquito   899 VALAVALVEFCMKSSNRS-SNRIPL------------------------SDTMTSNSNSKNR 935

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grik	NP_001262788.1	PBP1_iGluR_Kainate	35..395	CDD:380605	95/418 (23%)
		Periplasmic_Binding_Protein_Type_2	411..781	CDD:473866	170/382 (45%)
LOC1276693	XP_061500826.1	None