Protein Alignment Grik and LOC1273165

DIOPT Version :10

• Sequence 1: NP_001262788.1
• Gene: Grik / 42476
• FlyBaseID: FBgn0038840
• Length: 907
• Species: Drosophila melanogaster
• Sequence 2: XP_061503118.1
• Gene: LOC1273165 / 1273165
• VectorBaseID: AGAMI1_009742
• Length: 1024
• Species: Anopheles gambiae
• Alignment Length: 970
• Identity: 479/970 - (49%)
• Similarity: 657/970 - (67%)
• Gaps: 87/970 - (8%)

  Fly    13 FPLGFILTSLLLAF--------PGCRG------ERTNVGLVYENTDPDLEKIFHLAISKANEEN- 62
            ||: |:...|::||        .|..|      |...:|.:::....|.|..|..|:...|.|.
Mosquito    17 FPM-FLHRLLVVAFAFLLIGPTDGYNGDFDEPVEHIKIGGLFDGDTDDAELAFQYAVEAVNNEKL 80

  Fly    63 --EDLQLHGVSVSIEPGNSFETSKKLCKMLRQNLVAVFGPTSNLAARHAMSICDAKELPFLDTRW 125
              .:.||...:|.::.|:.|:.|||||::|:..:..:|||:|..:|.|..|:||.||:|.::|||
Mosquito    81 SYSNYQLEAQAVQVKYGDQFDVSKKLCRLLKTGVAGIFGPSSPKSALHVQSVCDEKEMPHIETRW 145

  Fly   126 DFGAQLPTINLHPHPATLGVALRDMVVALGWESFTIIYESGEYLPTVRELLQMYGTAGPTVTVRR 190
            |...:|||:||||||..:|....|:|||..|:.|||:||||.:||.:.:||:||...|.|||||:
Mosquito   146 DAYTKLPTLNLHPHPHIMGRVFLDLVVAFEWKDFTILYESGPWLPGISDLLKMYDPKGYTVTVRQ 210

  Fly   191 YELDLNGNYRNVLRRIRNADDFSFVVVGSMATLPEFFKQAQQVGLVTSDYRYIIGNLDWHTMDLE 255
            .:|.||||||.||||::.::|...::..|:.::||..||||||||:|..::.||.:||.||:|||
Mosquito   211 LDLGLNGNYRAVLRRVKLSEDKRIILACSIESMPEVLKQAQQVGLLTDHHQIIITSLDLHTIDLE 275

  Fly   256 PYQHAGTNITGLRLVSPDSEQVQEVAKALYESE-----EPFQNVS-CPLTNSMALVYDGVQLLAE 314
            |||::||||||:||:.|:.|::::||..|..|:     |....:: ..:....||:||.|.|.||
Mosquito   276 PYQYSGTNITGVRLIDPEEEKIKQVADFLNASQIAKTLELHDGLNPAKMRVKTALMYDAVLLFAE 340

  Fly   315 TYKHV-------NFRPVALSCNDDSAWDKGYTLVNYMKSLTLNGLTGPIRFDYEGLRTDFKLEVI 372
            ..||:       ...|::|.|:|.:.|..||:::|||||.|::|||..|:||::|.|:||.|::|
Mosquito   341 ALKHLIGSEPPRLLEPISLKCDDPTTWKNGYSVINYMKSSTIHGLTRSIKFDHQGHRSDFLLDLI 405

  Fly   373 ELAVSGMQKIGQWSGEDG--FQENRPAPAHSLEPDMRSLVNKSFVVITAISEPYGMLKETSEKLE 435
            ||..:|::|:|.|:..:|  |.......||::  |..:|.|::|:|:||||.||||||::..||.
Mosquito   406 ELGPAGLEKVGVWNSTEGLNFTRKTEQAAHAM--DDGTLQNRTFLVLTAISPPYGMLKDSPIKLS 468

  Fly   436 GNDQFEGFGIELIDELSKKLGFSYTWRLQEDNKYGGIDPKTGEWNGMLREIIDSRADMGITDLTM 500
            ||::||||||:||.|||..|||:||:.||||..||.::..|.:||||::|:::.|||:.|||||:
Mosquito   469 GNERFEGFGIDLIHELSLMLGFNYTFILQEDGVYGSLNRDTKKWNGMVQELLEWRADLAITDLTI 533

  Fly   501 TSERESGVDFTIPFMSLGIGILFRKPMKEPPKLFSFMSPFSGEVWLWLGLAYMGVSISMFVLGRL 565
            ||:|||.||||:|||:|||.||||||.||||.|||||||||.:|||:||.|||.||:|:|||||:
Mosquito   534 TSDRESAVDFTMPFMNLGISILFRKPTKEPPSLFSFMSPFSKQVWLYLGGAYMMVSMSLFVLGRI 598

  Fly   566 SPAEWDNPYPCIEEPTELENQFSFANCLWFSIGALLQQGSELAPKAYSTRAVAASWWFFTLILVS 630
            ||.||||||||||||.||||||||:|.:||:||||||||||:||||.:|||||:.|||||||:||
Mosquito   599 SPKEWDNPYPCIEEPEELENQFSFSNSMWFTIGALLQQGSEIAPKAPATRAVASIWWFFTLIMVS 663

  Fly   631 SYTANLAAFLTVESLVTPINDADDLSKNKGGVNYGAKIGGATFNFFKESNYPTYQRMYEFMRDNP 695
            |||||||||||||.:|:|||:|:||:...|.|.||||..|:|.:|||::.|.||.:||:||..|.
Mosquito   664 SYTANLAAFLTVEQVVSPINNAEDLAAAGGAVKYGAKRDGSTISFFKDAEYGTYAKMYQFMMANQ 728

  Fly   696 QYMTNTNQEGVDRVENSNYAFLMESTTIEYITERRCTLTQVGALLDEKGYGIAMRKNWPYRDTLS 760
            ..:|::|.||:.||:..|||||||||:||||.||.|.:||:|.|||:||||||||||.|||..||
Mosquito   729 DLLTSSNPEGLQRVKTENYAFLMESTSIEYIVERECDVTQIGGLLDDKGYGIAMRKNSPYRSALS 793

  Fly   761 QAVLEMQEQGLLTKMKTKWWQEKRGGGACSDADEDSGAVALEISNLGGVFLVMGVGSFFGIFVSL 825
            :|||.:||||:||.:|.|||:||||||||.:..|:.||:|||::|:||||:::.||....:|||.
Mosquito   794 EAVLRLQEQGVLTSLKRKWWKEKRGGGACENTMEEGGALALELANVGGVFVLLIVGCVAALFVSF 858

  Fly   826 LEMVLGVKERSDE--------------------------------------------------NQ 840
            .||:..|..|:.|                                                  ::
Mosquito   859 CEMLCDVHRRTRELKQSTSEDGAEELDMDNVGGVFFVLFVGCSFASLFGCCELFFVIAHRARRHK 923

  Fly   841 VSFKTELLDEIRFILQCSGNTKAVKYPKNSSRSNASSKSKGSSMSVDSLPEDTSEADASG 900
            |.|:.||:.|:||:.:|.||||.|::.|:||.|..:|...|...:..|  ..:|:.|.||
Mosquito   924 VPFREELMAELRFVAKCHGNTKPVRHRKSSSASGPNSLESGMESAEQS--ATSSKQDISG 981

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grik	NP_001262788.1	PBP1_iGluR_Kainate	35..395	CDD:380605	162/377 (43%)
		Periplasmic_Binding_Protein_Type_2	411..781	CDD:473866	250/369 (68%)
LOC1273165	XP_061503118.1	None