Protein Alignment Grik and LOC1270566

DIOPT Version :10

• Sequence 1: NP_001262788.1
• Gene: Grik / 42476
• FlyBaseID: FBgn0038840
• Length: 907
• Species: Drosophila melanogaster
• Sequence 2: XP_309276.5
• Gene: LOC1270566 / 1270566
• VectorBaseID: AGAMI1_006865
• Length: 939
• Species: Anopheles gambiae
• Alignment Length: 923
• Identity: 366/923 - (39%)
• Similarity: 548/923 - (59%)
• Gaps: 50/923 - (5%)

  Fly    17 FILTSLLLAFPGC---RGER-TNVGLVYENTDPD----LEKIFHLAISKANEENEDLQLHGVSVS 73
            |:...|||....|   .|:| ..||.::... ||    .|..|..||.:.|...:..:|..:...
Mosquito    12 FLSVILLLVHVLCGYVDGKREIPVGAIFHQV-PDHSYESEIAFRYAIERVNMHEKHFELVPIVRY 75

  Fly    74 IEPGNSFETSKKLCKMLRQNLVAVFGPTSNLAARHAMSICDAKELPFLDTRWD---FGA-----Q 130
            :.|.:|::|.:|:|::..:.:.|||||:|.|.:....|||...|:|.:.|.||   ||.     |
Mosquito    76 VSPDDSYKTERKVCELAAEGVTAVFGPSSILTSGIVGSICKTLEIPHIITHWDPEPFGGLDPDLQ 140

  Fly   131 LPTINLHPHPATLGVALRDMVVALGWESFTIIYESGEYLPTVRELLQMYGTAGPTVTVRRYELDL 195
            ..||||:|....|..||.|::|...|:||||||:|.|.|..::::||::|.:...:|||  ::|.
Mosquito   141 AMTINLYPEADVLSRALADLIVDYSWKSFTIIYDSDEGLMRLKDILQIHGPSDSPITVR--QIDD 203

  Fly   196 NGNYRNVLRRIRNADDFSFVVVGSMATLPEFFKQAQQVGLVTSDYRYIIGNLDWHTMDLEPYQHA 260
            |.:||.:|:.|:.:.:...::......:.|..:||::|.::.....|||.:||.||:|.|..:::
Mosquito   204 NPDYRPLLKDIQTSGESHIILEIRPDRILELLRQAKEVKMLEEYQSYIITSLDAHTIDFEELRYS 268

  Fly   261 GTNITGLRLVSPDSEQVQEVAKALYESEE-------PFQNVSCPLTNSMALVYDGVQLLAETYKH 318
            .:|||.|||:...|   .::..|:::.|:       .|:.....:....||..|.|::.|...:.
Mosquito   269 RSNITALRLMDTKS---FDIKNAVHDWEQGEARMKRQFRVSPEHVHTESALYNDAVKIYATAIRE 330

  Fly   319 VN----FRPVALSCNDDS--AWDKGYTLVNYMKSLTLNGLTGPIRFDYEGLRTDFKLEVIELAV- 376
            ::    ..|..|||...:  .|..|..::||||..|.:|:||||.||..|.|..|.|::|||:.
Mosquito   331 LDATEEITPSKLSCGSKNLRQWPFGLRIINYMKVKTEHGITGPIIFDDFGRRAHFHLDIIELSKD 395

  Fly   377 SGMQKIGQWSGEDGFQENRPAPAHSLEPDMRSLVNKSFVVITAISEPYGMLKE--TSEKLEGNDQ 439
            .|.:||..|....|....| :........:.||.||:|:|.:.|..|:.|.||  ..|.||||::
Mosquito   396 EGFKKIATWDPTHGVNYTR-SQGEVYSQIVESLQNKTFIVASRIGAPFLMFKEKKDGEFLEGNNR 459

  Fly   440 FEGFGIELIDELSKKLGFSYTWRLQEDNKYGGIDPKTGEWNGMLREIIDSRADMGITDLTMTSER 504
            |||:.:||||.:||.|||.|...|..|.|||..:..|.:|:|:::.::|.:||:.:.|||:|.||
Mosquito   460 FEGYSLELIDGISKILGFQYRMELVPDGKYGSYNKVTKKWDGLVKHLLDRKADLAVCDLTITYER 524

  Fly   505 ESGVDFTIPFMSLGIGILFRKPMKEPPKLFSFMSPFSGEVWLWLGLAYMGVSISMFVLGRLSPAE 569
            .:.||||:|||:|||.||:.||:::|..||||:||.|.:||::...||:|||:.:|||.|::||:
Mosquito   525 RTAVDFTMPFMTLGISILYAKPVQQPKDLFSFLSPLSLDVWIYTATAYLGVSVLLFVLSRMAPAD 589

  Fly   570 WDNPYPCIEEPTELENQFSFANCLWFSIGALLQQGSELAPKAYSTRAVAASWWFFTLILVSSYTA 634
            |:||:||.::..|:||.:...|.||.::|:::.||.::.|||.|||.||..||||.||::|||||
Mosquito   590 WENPHPCKQDNDEVENIWDMLNALWLTMGSIMGQGCDILPKAISTRLVAGMWWFFALIMLSSYTA 654

  Fly   635 NLAAFLTVESLVTPINDADDLSKNKGGVNYGAKIGGATFNFFKESNYPTYQRMYEFMRD-NPQYM 698
            |||||||:|.:...|..|:||:| :..:.||..:||:|..||:.||:.|||||:..|.. .|...
Mosquito   655 NLAAFLTMERMDATIESAEDLAK-QSKIKYGVLMGGSTMAFFQTSNFSTYQRMWASMESVRPSVF 718

  Fly   699 TNTNQEGVDRVENSN--YAFLMESTTIEYITERRCTLTQVGALLDEKGYGIAMRKNWPYRDTLSQ 761
            |.:|.||.|||....  ||||||||::||||||.|.|||:|.|||.|||||||..|.|||..:|.
Mosquito   719 TKSNDEGRDRVIKGKRMYAFLMESTSLEYITERYCDLTQIGGLLDSKGYGIAMPVNSPYRTAISG 783

  Fly   762 AVLEMQEQGLLTKMKTKWWQEKRGGGACSDADEDSGAVALEISNLGGVFLVMGVGSFFGIFVSLL 826
            |||:|||:|.|.::||:||:|.||||.|::....:|...|.|.|:||||:|:.:|.|....:.:|
Mosquito   784 AVLKMQEEGKLHQLKTRWWKEMRGGGQCTEVPNSAGENELGIGNVGGVFVVLALGCFCAFIIGIL 848

  Fly   827 EMVLGVKERSDENQVSFKTELLDEIRFILQCSGNTKAVKYPKNSSRSNASSKSKGSSMSVDSLPE 891
            |.:..|::.:.|.:::....|..|::|.|..|..:|.|.  ...|.|.||.||     |:.|..|
Mosquito   849 EFLWNVRKVAVEEKITPWDALKAEMKFALNISVTSKPVH--NTLSESTASDKS-----SLRSKSE 906

  Fly   892 DTSEADASGKHNH 904
            ....::.:|:.|:
Mosquito   907 SRRGSELTGRGNN 919

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grik	NP_001262788.1	PBP1_iGluR_Kainate	35..395	CDD:380605	123/385 (32%)
		Periplasmic_Binding_Protein_Type_2	411..781	CDD:473866	193/374 (52%)
LOC1270566	XP_309276.5	None