Protein Alignment Grik and grin3b

DIOPT Version :9

• Sequence 1: NP_001262788.1
• Gene: Grik / 42476
• FlyBaseID: FBgn0038840
• Length: 907
• Species: Drosophila melanogaster
• Sequence 2: XP_017952374.2
• Gene: grin3b / 100497172
• XenbaseID: XB-GENE-990106
• Length: 1005
• Species: Xenopus tropicalis
• Alignment Length: 986
• Identity: 209/986 - (21%)
• Similarity: 372/986 - (37%)
• Gaps: 220/986 - (22%)

  Fly    29 CR-----GERTNVGLV---YENTDPDLEKIFHLAISKANEENEDLQLHGVSVSIEPGNSFETSKK 85
            ||     |....:|.:   |.:|...::.:.. .||:.:....:|.|..||.:....:....::.
 Frog    27 CRILARIGHTVRLGALLPSYGHTQARIQNVLS-RISRTSWLPYNLSLEVVSGAPRDRSPASLTRW 90

  Fly    86 LCKML-RQNLVAVFG-PTSNLAARHAMSICDAKELPF-----------LDTRWDFGAQLPTINLH 137
            ||::| .|.:.||.. |.:.........:....|:||           |.|:..|..|:.|.:..
 Frog    91 LCQVLVAQGIAAVLAFPQAQEELLQLEFLSSFLEIPFISILEQEQIVPLATKNPFHLQMDTQSSV 155

  Fly   138 PHPATLGVALRDMVVAL----GWESFTIIYESGEYLPTVRELLQMYGTAGP--TVTVRRYELDLN 196
            .:       |.|:..::    .||...||                  |..|  :.:::||   |.
 Frog   156 EN-------LMDIFFSVLQNSSWEEVDII------------------TCHPWDSASIQRY---LT 192

  Fly   197 GNYRNVLRRIRN---ADDFSFVV-----VGSMATLPEF---------------FKQAQQVGLVTS 238
            .|...|.|.|.|   .|:.:.|.     ..||.. |:|               |:.|:..||...
 Frog   193 SNTTLVSRTILNIHPVDESALVPFLQQHFESMKN-PQFPMLLYGCDARRSSLVFRVARDCGLEAH 256

  Fly   239 DYRYIIGNLDWHTMDLEPYQHAGTNITGLRLVSPDSEQVQEVAKALYESEEPFQNVSCPLTNSMA 303
            ::.::||    |.::.|.....|        :.|......||::...|.
 Frog   257 EFHWMIG----HPLNGEEMTTEG--------MPPGLLAYGEVSRPTMEK---------------- 293

  Fly   304 LVYDGVQLLAETYK-HVNFRP-VAL-----SCNDDSA---WDKGYTLVNYMKSLTLNGLTGPIRF 358
            .:.|.|.|:..... .|:.|| :||     :|||...   ...|..|..::.:.:.:|.||.|..
 Frog   294 FIRDAVGLVTRAISAAVHVRPDLALIQSMVNCNDKQTKQNESSGSYLSRFLANTSFSGQTGQIYV 358

  Fly   359 DYEGLRTDFKLEVIEL-----------AVSGMQKIGQWSGEDGFQENR-----PAPAHSLEPDMR 407
            ....:.|:....:..|           .|.|.:: |:...|:|..::|     |||.......:|
 Frog   359 SNNLIHTEHHYRIWSLVRDSLGDPTWVTVGGWRQ-GKMEVEEGLWQSRIQQWEPAPGGFARTKLR 422

  Fly   408 SLVNKSFVVITAISEPYGMLKET-----------------------------------SEKLEGN 437
                    |:|.:..|:...:|.                                   |..||..
 Frog   423 --------VVTLVEHPFVFTREVDADGSCPAGQMCLDPRTNNSAVLDVLFEELNSPNGSVPLEYK 479

  Fly   438 DQFEGFGIELIDELSKKLGFSYTWRLQEDNKYGGIDPKTGEWNGMLREIIDSRADMGITDLTMTS 502
            ....|:.|:|:::||:.|.|.:...:..|.|||.  .|...|.|::.:::...|.|.:|..::.|
 Frog   480 TCCYGYCIDLLEKLSEDLRFDFELYIVGDGKYGA--RKGDRWTGLVGDLLSGAAHMAVTSFSINS 542

  Fly   503 ERESGVDFTIPFMSLGIGILFRKPMKEPPKLFSFMSPFSGEVWLWLGLAYMGVSISMFVLGR-LS 566
            .|.:.:|||.||.|..:|||.|......| :.:||.|....:|       :|:.:::.:... |:
 Frog   543 ARSTVIDFTSPFYSTSLGILVRMRDTASP-IGAFMWPLHWSMW-------VGIFVALHITALFLT 599

  Fly   567 PAEWDNPYPCIEEPTELENQFSFANCLWFSIGALL-QQGSELAPKAYSTRAVAASWWFFTLILVS 630
            ..||.:|:............||:::.|......|. :..|...||..:.|.:...|..|.|:::|
 Frog   600 FYEWKSPFGMTPHGRNRTKIFSYSSALNLCYAILFGRTVSSKTPKCCTGRVLMNLWAIFCLLVLS 664

  Fly   631 SYTANLAAFL----TVESLVTPINDADDLSKNKGGVNYGAKIGGATFNFFKESNYPTYQRMYEFM 691
            ||||||||.:    |.|:| :.|:| ..|.....|..:|.....:...:.|:|    :..|:.:|
 Frog   665 SYTANLAAVMVGDKTFEAL-SGIHD-PKLHHPSQGFRFGTVWESSAEQYIKKS----FPEMHNYM 723

  Fly   692 RDNPQYMTNTNQEGVDRVEN---SNYAFLMESTTIEY--ITERRCTLTQVGALLDEKGYGIAMRK 751
            |   ::......:||..::.   :..||:|:...::|  ..:..|.|..:|.....:||||.:.:
 Frog   724 R---KFSVPATSDGVHLLKTDPPTLNAFIMDKALLDYEVSIDSDCKLLTIGKPFAIEGYGIGLPQ 785

  Fly   752 NWPYRDTLSQAVLEMQEQGLLTKMKTKWWQEKRGGGACSDADEDSGAVALEISNLGGVFLVMGVG 816
            |.|....:|:.:...:..|.:..:..||::....|.......|   .:.:.|.:..|:|:::.:|
 Frog   786 NSPLTSNISEFISRYKSSGFMDTLHDKWYKMVPCGKRVYAVTE---TLQMGIYHFSGLFVLLCIG 847

  Fly   817 SFFGIFVSLLEMVL------GVKERSDENQVSFKTELLDEIRFILQCSGNTKAVKYPKNSSRSNA 875
            ....:..||:|.|:      .::.|   .:..:......:|...|..:...:....||.:.|.|.
 Frog   848 FCGSLLTSLMERVVYHLILPRIRRR---RRFKYWLHTSQKIHRALNMTCEDQDALSPKLNKRCNL 909

  Fly   876 SSKSKGSSMSV 886
            ...:.|:..||
 Frog   910 QKDATGAPQSV 920

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grik	NP_001262788.1	PBP1_iGluR_Kainate	37..391	CDD:107377	82/419 (20%)
		ANF_receptor	53..374	CDD:279440	74/372 (20%)
		Periplasmic_Binding_Protein_Type_2	411..781	CDD:304360	98/415 (24%)
		Lig_chan	543..816	CDD:278489	63/283 (22%)
grin3b	XP_017952374.2	PBP1_iGluR_NMDA_NR3	29..402	CDD:380600	84/431 (19%)
		PBP2_iGluR_NMDA_Nr3	418..814	CDD:270438	98/422 (23%)
		Lig_chan	582..848	CDD:395014	63/284 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910