Protein Alignment Grik and grik1

DIOPT Version :10

• Sequence 1: NP_001262788.1
• Gene: Grik / 42476
• FlyBaseID: FBgn0038840
• Length: 907
• Species: Drosophila melanogaster
• Sequence 2: XP_004912220.1
• Gene: grik1 / 100493949
• XenbaseID: XB-GENE-957124
• Length: 928
• Species: Xenopus tropicalis
• Alignment Length: 921
• Identity: 337/921 - (36%)
• Similarity: 516/921 - (56%)
• Gaps: 96/921 - (10%)

  Fly    22 LLLAF--------PGCRGERTNVGLVY---ENTDPDLEKI-FHLAISKANEENEDLQLHGVSVSI 74
            |||.|        |....:...:|.::   ||...::|:: |..|::..|.....:....::..|
 Frog    25 LLLPFLCALAAITPQASQQVLRIGGIFETVENEPINVEELAFKFAVTNINRNRTLMPNTTLTYDI 89

  Fly    75 EPGN---SFETSKKLCKMLRQNLVAVFGPTSNLAARHAMSICDAKELPFLDTRWDFGAQLPT--- 133
            :..|   |||.|::.|..|...:.|:|||:.:.:.....|||:|.|:|.:.|||    :.|:
 Frog    90 QRINLFDSFEASRRACDQLALGVAALFGPSHSSSVSAVQSICNALEVPHIQTRW----KHPSVDN 150

  Fly   134 -----INLHPHPATLGVALRDMVVALGWESFTIIYESGEYLPTVRELLQMYGTAGPTVTVRRYEL 193
                 |||||..|.:..|:.::|:...|::.|::||....|..::||::     .|:    ||.:
 Frog   151 KDSFFINLHPDYAAISRAVLELVLHYSWKTVTVVYEDSTGLIRLQELIK-----APS----RYNI 206

  Fly   194 DL--------NGNYRNVLRRIRNADDFSFVVVGSMATLPEFFKQAQQVGLVTSDYRYIIGNLDWH 250
            .:        |.:.|.:|:.::.:.:|..:...|..|..|..||...:|::|..|.|....:|..
 Frog   207 KIKIRQLPSGNKDARTLLKEMKKSREFYVIFDCSHETAAEILKQILSMGMMTEYYHYFFTTMDLF 271

  Fly   251 TMDLEPYQHAGTNITGLRLVSPDSEQVQEVAKALYESEEPFQNVSCP--------LTNSMALVYD 307
            .:|||||:::|.|:||.||::.|:.||..|.:..  |.|..|....|        :|...||:||
 Frog   272 ALDLEPYRYSGVNMTGFRLLNIDNPQVSSVVEKW--SMERLQAPPKPETGLLDGMMTTDAALMYD 334

  Fly   308 GVQLLA-ETYKHVNFRPVALSCNDDSAWDKGYTLVNYMKSLTLNGLTGPIRFD-YEGLRTDFKLE 370
            .|.::| .|.:.......:|.|:....|..|...::.:|....:||||.|.|: .:|||.||.::
 Frog   335 AVYMVAVATQRATQMTVSSLQCHRHKPWRFGPRFMSLIKEARWDGLTGRITFNRTDGLRRDFDMD 399

  Fly   371 VIELAVSGMQ---------------KIGQWSGEDGFQ--ENRPAPAHSLEPDMRSLVNKSFVVIT 418
            :|.|...||:               |:|.|:...|..  :|....:.::..   ||.|::.:|.|
 Frog   400 IISLKEDGMEKAAGETVNHLNKVWKKVGVWNSNTGLNMTDNLKDKSTNITD---SLANRTLIVTT 461

  Fly   419 AISEPYGMLKETSEKLEGNDQFEGFGIELIDELSKKLGFSYTWRLQEDNKYGGIDPKTGEWNGML 483
            .:.:||.|.:::.:.|.|||:|||:.::|:.|||..|||:|..||..|.|||..:.| ||||||:
 Frog   462 ILEDPYVMFRKSDKPLYGNDRFEGYCLDLLKELSNILGFTYEVRLVVDGKYGAQNDK-GEWNGMV 525

  Fly   484 REIIDSRADMGITDLTMTSERESGVDFTIPFMSLGIGILFRKPMKEPPKLFSFMSPFSGEVWLWL 548
            ||:||.:||:.:..||:|..||..:||:.|||:|||.||:|||....|.:|||::|.|.::|:::
 Frog   526 RELIDHKADLAVAPLTITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPDIWMYV 590

  Fly   549 GLAYMGVSISMFVLGRLSPAEWDNPYPCIEEPTELENQFSFANCLWFSIGALLQQGSELAPKAYS 613
            .||.:|||..:||:.|.:|.||.||:||..:...:||.|:..|..||.:|||:||||||.|||.|
 Frog   591 LLACLGVSCVLFVIARFTPYEWYNPHPCNPDSDVVENNFTLLNSFWFGVGALMQQGSELMPKALS 655

  Fly   614 TRAVAASWWFFTLILVSSYTANLAAFLTVESLVTPINDADDLSKNKGGVNYGAKIGGATFNFFKE 678
            ||.|...|||||||::||||||||||||||.:.:||:.||||:| :..:.|||...|:|..|||:
 Frog   656 TRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAK-QTKIEYGAVRDGSTMTFFKK 719

  Fly   679 SNYPTYQRMYEFMRDNPQ-YMTNTNQEGVDRVENSNYAFLMESTTIEYITERRCTLTQVGALLDE 742
            |...||::|:.||....| .:...|.||:.||..::||.|||||:|||:|:|.|.|||:|.|:|.
 Frog   720 SKISTYEKMWAFMSSRQQTALVKNNDEGIQRVLTTDYALLMESTSIEYVTQRNCNLTQIGGLIDS 784

  Fly   743 KGYGIAMRKNWPYRDTLSQAVLEMQEQGLLTKMKTKWWQEKRGGGACSDADEDSGAVALEISNLG 807
            ||||:......||||.::.|:|::||:|.|..||.|||   ||.| |.:.|... |.||.:.|:|
 Frog   785 KGYGVGTPIGSPYRDKITIAILQLQEEGKLHMMKEKWW---RGNG-CPEEDSKE-ASALGVENIG 844

  Fly   808 GVFLVMGVGSFFGIFVSLLEMVLGVKERSDENQVSFKTELLDEIRFILQCSGNTKAVKYPKNSSR 872
            |:|:|:..|....:||::.|.:...::.||..|......:::|:..         ::|:||   |
 Frog   845 GIFIVLAAGLVLSVFVAIGEFIYKSRKNSDIEQCLSFNAIMEELGI---------SLKHPK---R 897

  Fly   873 SNASSKSKGSS 883
            .....|:||.|
 Frog   898 LKKKPKAKGRS 908

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grik	NP_001262788.1	PBP1_iGluR_Kainate	35..395	CDD:380605	112/409 (27%)
		Periplasmic_Binding_Protein_Type_2	411..781	CDD:473866	187/370 (51%)
grik1	XP_004912220.1	PBP1_iGluR_Kainate	46..439	CDD:380605	112/407 (28%)
		Periplasmic_Binding_Protein_Type_2	454..823	CDD:473866	188/373 (50%)