Protein Alignment Grik and grik3

DIOPT Version :10

• Sequence 1: NP_001262788.1
• Gene: Grik / 42476
• FlyBaseID: FBgn0038840
• Length: 907
• Species: Drosophila melanogaster
• Sequence 2: XP_017206939.1
• Gene: grik3 / 100334689
• ZFINID: ZDB-GENE-211021-1
• Length: 991
• Species: Danio rerio
• Alignment Length: 902
• Identity: 330/902 - (36%)
• Similarity: 510/902 - (56%)
• Gaps: 66/902 - (7%)

  Fly    36 VGLVYENTDPDL------EKIFHLAISKANEENEDLQLHGVSVSIEPGN---SFETSKKLCKMLR 91
            :|.::|.||..:      |..|..|::..|.....|....::..|:..|   |||.|:|.|..|.
Zfish    33 IGGIFEQTDGPVALVSSEELAFKFAVNNINRNRTLLPNTTLTYDIQRINIYDSFEASRKACDQLS 97

  Fly    92 QNLVAVFGPTSNLAARHAMSICDAKELPFLDTRW---------DFGAQLPTINLHPHPATLGVAL 147
            ..:||:|||:.:.::....|||:|.|:|.:..||         .|.|     ||:|..::|..|:
Zfish    98 LGVVAIFGPSHSSSSNAVQSICNALEVPHIQVRWKHHPMDNRDTFYA-----NLYPDYSSLSYAI 157

  Fly   148 RDMVVALGWESFTIIYESGEYLPTVRELLQMYGTAGPTVTVRRYELDLNGNYRNVLRRIRNADDF 212
            .|:|..|.|::.|::|:....|..::||:.........:.:|:..:| ..:.|.:|:.::.:.:|
Zfish   158 LDLVQFLKWKTATVVYDDSTGLIRLQELIMAPSRYNIRLKIRQLPMD-TVDTRPLLKEMKRSREF 221

  Fly   213 SFVVVGSMATLPEFFKQAQQVGLVTSDYRYIIGNLDWHTMDLEPYQHAGTNITGLRLVSPDSEQV 277
            ..:...|.....:..||||.:|::|..|.||...||...::||||:..|.|:||.|:::.|:.||
Zfish   222 RIIFDCSHTMAAQILKQAQMMGMMTEYYHYIFTTLDLMAINLEPYRFCGVNMTGFRILNVDNPQV 286

  Fly   278 QE-VAKALYESEEP-------FQNVSCPLTNSMALVYDGVQLLAETYKHVNFRPV-ALSCNDDSA 333
            .. |.|...|.:.|       .:.:   :|...||.||.|.:::.:|:|.....| :|.|:....
Zfish   287 ASIVEKWSLERQIPPKPDSGLLEGI---MTTDAALTYDAVHIVSVSYQHAPQMTVNSLQCHRHKP 348

  Fly   334 WDKGYTLVNYMKSLTLNGLTGPIRFD-YEGLRTDFKLEVIELAVSGMQKIGQWSGEDGFQENRPA 397
            |..|...::::|....:||||.:.|: ..||||||.|:::.|...|:||:|:||...|..... .
Zfish   349 WRFGGRFMSFIKESHWDGLTGRLCFNRTTGLRTDFDLDIVSLKEDGLQKVGKWSASGGLNITE-V 412

  Fly   398 PAHSLEPDMRSLVNKSFVVITAISEPYGMLKETSEKLEGNDQFEGFGIELIDELSKKLGFSYTWR 462
            |..:......||.|:|.|:.|.:.|||.|||::.:.|.|||:||||.|:|:.||:..|||||...
Zfish   413 PRQNGMNITDSLSNRSLVITTILEEPYVMLKKSDKALVGNDRFEGFCIDLLKELASILGFSYEIH 477

  Fly   463 LQEDNKYGGIDPKTGEWNGMLREIIDSRADMGITDLTMTSERESGVDFTIPFMSLGIGILFRKPM 527
            |..|.|||..|.| |:||||:||:::.|||:.:..||:|..||..:||:.||::.||.||:|||.
Zfish   478 LVPDGKYGFQDDK-GQWNGMIRELMEHRADLAVAPLTITFMREKAIDFSKPFLNTGISILYRKPN 541

  Fly   528 KEPPKLFSFMSPFSGEVWLWLGLAYMGVSISMFVLGRLSPAEWDNPYPCIEEPTELENQFSFANC 592
            ......|||::|.:.::|:::.|||:|||..:||:.|.||.||.:.:||......:||.|:..|.
Zfish   542 STNSGFFSFLNPMTPDIWVYILLAYLGVSCVLFVIARFSPYEWYDAHPCNPGSDVVENNFTLLNS 606

  Fly   593 LWFSIGALLQQGSELAPKAYSTRAVAASWWFFTLILVSSYTANLAAFLTVESLVTPINDADDLSK 657
            .||.:|:|:||||||.|||.|||.:...|||||||::||||||||||||||.:.:|::.||||:|
Zfish   607 FWFGVGSLMQQGSELMPKALSTRIIGGIWWFFTLIIISSYTANLAAFLTVERMDSPVDSADDLAK 671

  Fly   658 NKGGVNYGAKIGGATFNFFKESNYPTYQRMYEFM--RDNPQYMTNTNQEGVDRVENSNYAFLMES 720
             :..:.||....|||.:|||:|...|:::|:.||  |.:..::.:. ::|:.||..|:||.||||
Zfish   672 -QTKIEYGVVKDGATMSFFKKSRVSTFEKMWAFMSSRQSTSFVKSI-EDGIQRVLKSDYALLMES 734

  Fly   721 TTIEYITERRCTLTQVGALLDEKGYGIAMRKNWPYRDTLSQAVLEMQEQGLLTKMKTKWWQEKRG 785
            |||||:|.|.|.|||||.::|.|||||...|..||||.::.|:|.:.|.|.|..:|.|||    .
Zfish   735 TTIEYVTRRNCNLTQVGGIIDSKGYGIGTPKGSPYRDKITIAILGILEDGRLHMLKEKWW----S 795

  Fly   786 GGACSDADEDSGAVALEISNLGGVFLVMGVGSFFGIFVSLLEMVLGVKERSDENQVSFKTELLDE 850
            |.:|.: ||......:.|.||||:|:|:..|....:||::.|.:..:::.::..||
Zfish   796 GSSCLE-DERYETGPMGIQNLGGIFIVLASGLVLSVFVAIGEFIYKLRKTAEREQV--------- 850

  Fly   851 IRFILQC-SGNTKAVKYPKNSSRSN----ASSKSKGSSMSVDSLPEDTSEADASGKH 902
               .||| .|..:.|.:.:.:..:.    |:|.::.......:|.:..|.| ..|:|
Zfish   851 ---FLQCGDGRDQTVVHVRETGEAQAPPAAASHAEDGRSDQHALLQRPSPA-RKGQH 903

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grik	NP_001262788.1	PBP1_iGluR_Kainate	35..395	CDD:380605	114/386 (30%)
		Periplasmic_Binding_Protein_Type_2	411..781	CDD:473866	183/371 (49%)
grik3	XP_017206939.1	PBP1_iGluR_Kainate	32..410	CDD:380605	114/385 (30%)
		Periplasmic_Binding_Protein_Type_2	426..794	CDD:473866	182/370 (49%)