Protein Alignment Grik and si:ch211-264f5.8

DIOPT Version :10

• Sequence 1: NP_001262788.1
• Gene: Grik / 42476
• FlyBaseID: FBgn0038840
• Length: 907
• Species: Drosophila melanogaster
• Sequence 2: XP_017207885.1
• Gene: si:ch211-264f5.8 / 100331381
• ZFINID: ZDB-GENE-081104-209
• Length: 1063
• Species: Danio rerio
• Alignment Length: 876
• Identity: 301/876 - (34%)
• Similarity: 489/876 - (55%)
• Gaps: 81/876 - (9%)

  Fly    30 RGERTNVGLVYENTDPDLEKIFHLAISKANEENEDLQLHGVSVSIEPGNSFETSKKLCKMLRQNL 94
            ||||..:.|..||.:..:|     ..::|..|.:..:|       :..:.:||:..:|::|.:.:
Zfish    50 RGERLALALARENINSLME-----GPARARVEVDIFEL-------QRDSQYETTDTMCQILPKGV 102

  Fly    95 VAVFGPTSNLAARHAMS-ICDAKELPFLDTRWDFGAQLP-----TINLHPHPATLGVALRDMVVA 153
            |:|.||.|:.|:...:| ||..||:|.:....:...:||     ::.|:|....|.:|:..::.:
Zfish   103 VSVIGPASSPASGSTVSHICGEKEIPHIKIGPEETPRLPYLRFASVTLYPSNEDLSLAIGAILRS 167

  Fly   154 LGWESFTIIYESGEYLPTVRELLQMYGTAGPTVTVRRYELDLNGNYRNVLRRIRNADDFSFVVVG 218
            .|:.:.::|....|.|..:.||::.:..:..|::||.  ||.|.:...:|:.||: |..:.:::.
Zfish   168 FGYPTASLICAKAECLLRLEELVRHFLISRETLSVRM--LDENLDPTPLLKEIRD-DKVATIIID 229

  Fly   219 SMATLP-EFFKQAQQVGLVTSDYRYIIGNLDWHTMDLEPYQHAGTNITGLRLVSPDSEQVQEVAK 282
            :.|::. ...|:|.::|:.::.|:||:..:|:..:.|:...:..:||.|..:::.......|..:
Zfish   230 ANASVSILILKKASELGMTSAFYKYILTTMDFPLLRLDDVVNDQSNIVGFSMLNNSHPFYLEFIR 294

  Fly   283 ALYESEEPFQNVS----CPLTN------SMALVYDGVQLLAETYKHVN------FRPVALSCNDD 331
            :|        |:|    |.|:.      |.||::|.|.::....:.:|      .:|  |||...
Zfish   295 SL--------NLSWREGCDLSPYPGPALSSALMFDAVHVVVGAVRELNRSQEIGVKP--LSCTSS 349

  Fly   332 SAWDKGYTLVNYMKSLTLNGLTGPIRFDYEGLRTDFKLEVIELAVSGMQKIGQWSGEDGFQENRP 396
            ..|..|.:|:||::.:..:||||.:.|:.:|.||::.|.::|....|.::||.|      ..|..
Zfish   350 LIWQHGTSLMNYLRMVEYDGLTGRVEFNSKGQRTNYTLRILEKFKGGHKEIGVW------YSNNT 408

  Fly   397 APAHSLEPDM---RSLVNKSFVVITAISEPYGMLKETSEKLEGNDQFEGFGIELIDELSKKLGFS 458
            ...:|...|:   .:|.||:..|.|.:..||.|.||..:..:|:||:|||.::::.||:..|.||
Zfish   409 LAMNSTSLDINTSETLANKTLTVTTILENPYVMRKENYQDFQGSDQYEGFCVDMLRELADILKFS 473

  Fly   459 YTWRLQEDNKYGGIDPKTGEWNGMLREIIDSRADMGITDLTMTSERESGVDFTIPFMSLGIGILF 523
            :..:|.:|..||..:| .|.|.||:.|:|:.:||:.:...|:|||||..:||:.|||:|||.||:
Zfish   474 FRIKLVDDGLYGAPEP-NGSWTGMVGELINRKADLAVAGFTITSEREKVIDFSKPFMNLGISILY 537

  Fly   524 RKPMKEPPKLFSFMSPFSGEVWLWLGLAYMGVSISMFVLGRLSPAEWDNPYPCIEEPTE-LENQF 587
            |..:...|..|||:.|||..|||::.|||:.||..:|:..||||.||.||:||..|..: ||||:
Zfish   538 RVHIGRKPGYFSFLDPFSPAVWLFMLLAYLAVSCVLFLAARLSPYEWYNPFPCWRERRDLLENQY 602

  Fly   588 SFANCLWFSIGALLQQGSELAPKAYSTRAVAASWWFFTLILVSSYTANLAAFLTVESLVTPINDA 652
            :..|.|||.||..:|||||:.|:|.|||.|:..||.||||::|||||||||||||:.:..||..|
Zfish   603 TLGNSLWFPIGGFMQQGSEIMPRALSTRCVSGVWWAFTLIIISSYTANLAAFLTVQRMEVPIESA 667

  Fly   653 DDLSKNKGGVNYGAKIGGATFNFFKESNYPTYQRMYEFM-RDNPQYMTNTNQEGVDRVENSNYAF 716
            :||: ::..:.||...||:|..||..|.|.|||||:.:| ...|.....:.:||:.||.||.|||
Zfish   668 EDLA-DQTNIQYGTIQGGSTMTFFMNSRYQTYQRMWNYMYSKQPSVFVKSTEEGIARVLNSKYAF 731

  Fly   717 LMESTTIEYITERRCTLTQVGALLDEKGYGIAMRKNWPYRDTLSQAVLEMQEQGLLTKMKTKWWQ 781
            |:|||..||.....|.|||:|.|||.|||||.|....|:||.::..:|::||...|..:|.:||:
Zfish   732 LLESTMNEYHRRLNCNLTQIGGLLDTKGYGIGMPLGSPFRDEITLGILQLQENNRLEILKRRWWE 796

  Fly   782 EKRGGGACSDADEDSGAVALEISNLGGVFLVMGVGSFFGIFVSLLEMVLGVKERSDENQ------ 840
                ||.|. .:||..|..|.:.|:||:|:|:..|....:||:::|.|...:..::.::
Zfish   797 ----GGKCL-KEEDHRAKGLGMDNIGGIFVVLICGLIIAVFVAIMEFVWSTRRSAETDEVRPHPC 856

  Fly   841 ---------VSFKTELLDEIRFILQCSGNTK 862
                     ||...|::.|.|.::.|..|::
Zfish   857 PVRNHRHARVSVCQEMMTEFRNVISCKKNSR 887

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grik	NP_001262788.1	PBP1_iGluR_Kainate	35..395	CDD:380605	92/382 (24%)
		Periplasmic_Binding_Protein_Type_2	411..781	CDD:473866	176/371 (47%)
si:ch211-264f5.8	XP_017207885.1	PBP1_iGluR_Kainate_KA1_2	35..413	CDD:380616	97/393 (25%)
		Periplasmic_Binding_Protein_Type_2	426..796	CDD:473866	176/371 (47%)