Protein Alignment Grik and grid1

DIOPT Version :9

• Sequence 1: NP_001262788.1
• Gene: Grik / 42476
• FlyBaseID: FBgn0038840
• Length: 907
• Species: Drosophila melanogaster
• Sequence 2: NP_001096470.1
• Gene: grid1 / 100125089
• XenbaseID: XB-GENE-990290
• Length: 1009
• Species: Xenopus tropicalis
• Alignment Length: 965
• Identity: 257/965 - (26%)
• Similarity: 434/965 - (44%)
• Gaps: 145/965 - (15%)

  Fly    22 LLLAFP---GCRGERT----NVGLVYENTDPDLEKIFHLAISKANEENEDLQLHGVSVS---IEP 76
            :|..||   .|...|.    ::|.::|......:::|.||:|..:..::.||...::.|   ||.
 Frog     5 MLCLFPWIFQCLSVRADSIIHIGAIFEENAVKDDEVFQLAVSDLSLNDDILQSEKITYSIKFIEA 69

  Fly    77 GNSFETSKKLCKMLRQNLVAVFGPTSNLAARHAMSICDAKELPFLDTRWDFGAQLPTI-NLHPHP 140
            .|.|:..::.|.::.|.::|:...|...:|....|:.||..:|.:..:.:.|....|: ..:|.|
 Frog    70 NNPFQAVQEACDLMTQGILALVTSTGCASANALQSLTDAMHIPHIFVQRNSGGSPRTVCQFNPSP 134

  Fly   141 A----TLG----VALRD----MVVALGWESFTIIYESGEYLPTVRELLQMYGTAGPTVTVRRYEL 193
            .    ||.    |.|.|    :|..|.|:.|.:.|:|...:..::..|......|..|::::.:.
 Frog   135 EGEEYTLAARPPVRLNDVMLKLVTELRWQKFIVFYDSDYDIRGLQGFLDQASRLGLDVSLQKVDR 199

  Fly   194 DLN---------------GNYRNVLRRIRNADDFSFVVVGSMATLPEFFKQAQQVGLVTSDYRYI 243
            :::               ..||:.|||.        :::.|......|..:|.:..|.:.|..::
 Frog   200 NISRVFATLFTSMKTEELNRYRDTLRRA--------ILLLSPRGAQSFISEAVETNLASKDSHWV 256

  Fly   244 IGNLDWHTMDLEPYQHAGT-NITGLRLVSPDSEQVQEVAKALYESEEPFQNVSCPLTN------- 300
            ..|.:.:..::....|:.. .||.:|.:.|..:.               .|:.|...|
 Frog   257 YVNEEINDAEIVELVHSALGRITVIRQIFPSLKD---------------NNIRCVRNNHRIASLP 306

  Fly   301 -------------SMALVYDGVQLLAETY-KHVNFRP----VALSCNDDSA--WDKGYTLVNYMK 345
                         |...:||.|.:||..: :.:..|.    .:|:|...|.  |:.|.::::.:|
 Frog   307 CDPQEGYLQMLQVSNLYLYDSVLMLANAFHRKLEDRKWHSMASLNCMRKSTKPWNGGRSMLDTIK 371

  Fly   346 SLTLNGLTGPIRFDYEGLRTDFKLEVIELAVS-----GMQKIGQWSGEDGFQ---ENRPAPAHSL 402
            ...:.||||.:.|...|.....:.|::..:.|     .::::..|....||.   :.:|     |
 Frog   372 KGRITGLTGIMEFKEAGANPHVQFEILGTSYSETFGKDVRRLATWDSMKGFNGSLQEKP-----L 431

  Fly   403 EPDMRSLVNKSFVVITAISEPYGMLKETSEKLEGN-DQFEGFGIELIDELSKKLGFSYTWRLQED 466
            ..|::.|..|   |:|.:.||:.|:   :|.:.|. .:::||.||::||||.:|||.|......|
 Frog   432 NNDLQGLTLK---VVTVLEEPFVMV---AENILGQPKRYKGFSIEILDELSNRLGFKYEIYQAPD 490

  Fly   467 NKYGGIDPKTGEWNGMLREIIDSRADMGITDLTMTSERESGVDFTIPFMSLGIGILFRKPMKEPP 531
            .|||. ....|.||||:.|:|:.|||:.|:.:|:|.|||:.||||..::...:|||.:|| :|..
 Frog   491 GKYGH-QLSNGSWNGMIGELINKRADIAISAITITPERENVVDFTKRYLDYSVGILIKKP-EERI 553

  Fly   532 KLFSFMSPFSGEVWLWLGLAYMGVSISMFVLGRLSPAEWDNPYPCIEEPTELENQFSFANCLWFS 596
            .:||..:||...||..:......|.:.:|||.|:......|     ...|......:..:.:|..
 Frog   554 NIFSLFAPFDFAVWACIAAVIPVVGVLIFVLNRIQAVRAQN-----SSQTSQSTSSTLHSAIWIV 613

  Fly   597 IGALLQQGSELAPKAYSTRAVAASWWFFTLILVSSYTANLAAFLTVESLVTPINDADDLSKNKGG 661
            .||.:|||.|.|..:.:.|.|..|||.||||:.|||||||||||||..:..||....||:| :..
 Frog   614 YGAFVQQGGESAANSVAMRIVMGSWWLFTLIVCSSYTANLAAFLTVSRMDNPIRTFQDLAK-QVD 677

  Fly   662 VNYGAKIGGATFNFFKE--SNYPTYQRMY-EFMR--------DNPQYMTNTNQEGVDRVENSNYA 715
            :.||.....:.:.:||.  :|.....|.: |..|        ||   ..::..||:.:.:..|||
 Frog   678 LPYGTVKDSSVYEYFKSKGTNTLVQDRTFAELWRTIGKNNGSDN---CVSSPSEGIRKAKRGNYA 739

  Fly   716 FLMESTTIEY--ITERRCTLTQVGALLDEKGYGIAMRKNWPYRDTLSQAVLEMQEQGLLTKMKTK 778
            ||.:.|.:||  :|:..|::...|..:..||||||::...||||..||.:||.|:.|.|..:|.|
 Frog   740 FLWDVTVVEYAALTDDECSVAVTGNTISSKGYGIALQHGSPYRDIFSQRILEFQDSGRLDVLKEK 804

  Fly   779 WWQEKRGGGAC---SDADEDSGAVALEISNLGGVFLVMGVGSFFGIFVSLLEMVLGVKERSDENQ 840
            ||...   |.|   |..:..:...||::.:..|||.::.:|......|:.||:.........::.
 Frog   805 WWPRT---GRCDLNSHNNAQNDGKALKLHSFAGVFCILAIGLLLACLVAALELWWNSNRCRQDSP 866

  Fly   841 VSFKTELLDEIRFILQCSGNTKAVKYPKNSSRSNASSKSKGSSMSVDSLPEDTSE 895
            ...|...|:::...|    |:...:...:...|.||.:.  |::.:..:|..|.|
 Frog   867 KEDKEVNLEQVHRRL----NSLIDEDMAHKQISTASIEI--SALEIGGMPSQTLE 915

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grik	NP_001262788.1	PBP1_iGluR_Kainate	37..391	CDD:107377	81/417 (19%)
		ANF_receptor	53..374	CDD:279440	76/379 (20%)
		Periplasmic_Binding_Protein_Type_2	411..781	CDD:304360	141/383 (37%)
		Lig_chan	543..816	CDD:278489	96/288 (33%)
grid1	NP_001096470.1	PBP1_iGluR_delta_1	25..424	CDD:107387	83/421 (20%)
		ANF_receptor	39..400	CDD:279440	77/383 (20%)
		PBP2_iGluR_delta_1	437..807	CDD:270448	142/386 (37%)
		Lig_chan	565..842	CDD:278489	96/288 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000021
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000