DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ktl and LOC681355

DIOPT Version :9

Sequence 1:	NP_001303467.1	Gene:	Ktl / 42475	FlyBaseID:	FBgn0038839	Length:	228	Species:	Drosophila melanogaster
Sequence 2:	XP_003752068.1	Gene:	LOC681355 / 681355	RGDID:	1596735	Length:	292	Species:	Rattus norvegicus

Alignment Length:	279	Identity:	110/279 - (39%)
Similarity:	151/279 - (54%)	Gaps:	58/279 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 PEIIELNVGGVSYTTTLATLLQDKSTLLAELFG-EGRDSLAKDSKGRYFLDRDGVLFRYILDFLR 65
            ||||||||||..|.|...||:....:.|.|:|. :...||.:|:|||:|:||||.||||:||::|
  Rat    20 PEIIELNVGGQVYITRYPTLISIPGSRLWEMFSVKNPCSLIQDNKGRFFIDRDGFLFRYVLDYMR 84

  Fly    66 DKALHLPEGFRERQRLLREAEHFKLTAMLECI---------------RSERDARPP--------- 106
            |..:.||:.|.|..||.||||:|||..:.:.:               :.:.|...|
  Rat    85 DMQVVLPDHFPECGRLHREAEYFKLPELAKMLALKMNKLNSIGNDSCQIDLDELSPSIDTTFNFS 149

  Fly   107 ---------------------------GCITIGYRGSFQFGKDGLADVKFRKLSRILVCGRVAQC 144
                                       |.||||||||:..|:|...|.|||:::||:|||:::..
  Rat   150 STNSIHISGPDNPVVLTAAPGSELKKAGFITIGYRGSYTLGRDSQTDAKFRRVARIMVCGKISLA 214

  Fly   145 REVFGDTLNESRDPDHGGTDRYTSRFFLKHCYIEQAFDNLHDHGYRMAGSCGSGTAGSAAEPKPG 209
            :||||||||||||||. ..:|||||::||..::|||||.|.|.|:.|.....:||.....:
  Rat   215 KEVFGDTLNESRDPDR-PPERYTSRYYLKFTFLEQAFDKLADAGFHMVACNSTGTCTVTHD---- 274

  Fly   210 VDTEENRWNHYNEFVFIRD 228
             .|::..|..|.|:||.|:
  Rat   275 -QTDDRIWTSYTEYVFYRE 292

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ktl	NP_001303467.1	BTB	5..97	CDD:197585	46/92 (50%)
Ktl	NP_001303467.1	BTB	5..91	CDD:295341	45/86 (52%)
LOC681355	XP_003752068.1	BTB	23..113	CDD:295341	46/89 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	124	1.000	Domainoid score	I5410
eggNOG	1	0.900	-	-		E1_KOG2723
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	183	1.000	Inparanoid score	I3869
OMA	1	1.010	-	-		QHG49144
OrthoDB	1	1.010	-	-		D1579292at2759
OrthoFinder	1	1.000	-	-		FOG0001212
OrthoInspector	1	1.000	-	-		oto97197
orthoMCL	1	0.900	-	-		OOG6_106901
Panther	1	1.100	-	-	O	PTHR14499
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X239
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	12.880