Protein Alignment Ktl and KCTD16

DIOPT Version :10

• Sequence 1: NP_650926.1
• Gene: Ktl / 42475
• FlyBaseID: FBgn0038839
• Length: 228
• Species: Drosophila melanogaster
• Sequence 2: NP_065819.1
• Gene: KCTD16 / 57528
• HGNCID: 29244
• Length: 428
• Species: Homo sapiens
• Alignment Length: 262
• Identity: 116/262 - (44%)
• Similarity: 160/262 - (61%)
• Gaps: 41/262 - (15%)

  Fly     2 PEIIELNVGGVSYTTTLATLLQDKSTLLAELFGEGRDS---LAKDSKGRYFLDRDGVLFRYILDF 63
            ||::||||||..|.|..:||:....:||.::|...||:   ||||||||:|:||||.|||||||:
Human    24 PEVVELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRDTANDLAKDSKGRFFIDRDGFLFRYILDY 88

  Fly    64 LRDKALHLPEGFRERQRLLREAEHFKLTAMLECIRSER--------------------DAR--PP 106
            |||:.:.||:.|.|:.||.||||:|:|..:::.:..:.                    |.|  ||
Human    89 LRDRQVVLPDHFPEKGRLKREAEYFQLPDLVKLLTPDEIKQSPDEFCHSDFEDASQGSDTRICPP 153

  Fly   107 ----------GCITIGYRGSFQFGKDGLADVKFRKLSRILVCGRVAQCREVFGDTLNESRDPDHG 161
                      |.||:|||||...|::|.||.|||::.|||||||::..:||||:|||||||||.
Human   154 SSLLPADRKWGFITVGYRGSCTLGREGQADAKFRRVPRILVCGRISLAKEVFGETLNESRDPDR- 217

  Fly   162 GTDRYTSRFFLKHCYIEQAFDNLHDHGYRMAGSCGSGTAGSAAEPKPGVDTEENRWNHYNEFVFI 226
            ..:||||||:||..::|:|||.|.:.|:.|. :|.|....|.....    |::..|:.|.|:||.
Human   218 APERYTSRFYLKFKHLERAFDMLSECGFHMV-ACNSSVTASFINQY----TDDKIWSSYTEYVFY 277

  Fly   227 RD 228
            |:
Human   278 RE 279

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ktl	NP_650926.1	BTB_POZ_KCTD8-like	1..99	CDD:349676	52/99 (53%)
		H1_KCTD12-like	106..227	CDD:409026	60/130 (46%)
KCTD16	NP_065819.1	BTB_POZ_KCTD16	23..125	CDD:349706	52/100 (52%)
		H1_KCTD16	160..280	CDD:409030	60/126 (48%)