Protein Alignment Ktl and kctd12.2

DIOPT Version :10

• Sequence 1: NP_650926.1
• Gene: Ktl / 42475
• FlyBaseID: FBgn0038839
• Length: 228
• Species: Drosophila melanogaster
• Sequence 2: NP_001029191.1
• Gene: kctd12.2 / 553403
• ZFINID: ZDB-GENE-060117-4
• Length: 271
• Species: Danio rerio
• Alignment Length: 263
• Identity: 115/263 - (43%)
• Similarity: 158/263 - (60%)
• Gaps: 43/263 - (16%)

  Fly     3 EIIELNVGGVSYTTTLATLLQDKSTLLAELFGEGRDS-LAKDSKGRYFLDRDGVLFRYILDFLRD 66
            |||||||||..|.|..:|||...::||..:|.:.:.: |..|||||:||||||.|||||||:|||
Zfish    15 EIIELNVGGQVYVTRHSTLLSVPNSLLWTMFSQKKPAELTTDSKGRFFLDRDGFLFRYILDYLRD 79

  Fly    67 KALHLPEGFRERQRLLREAEHFKLTAMLECIR---------SER--------------------- 101
            :.|.||:.|:|:..||:|||:|:|..:.:.::         ||.
Zfish    80 QTLVLPDYFKEKASLLKEAEYFQLQDLAKRLKPAVSKENSISEEVCQSDPEEAALAGTSMTCTGP 144

  Fly   102 -----DARPPGCITIGYRGSFQFGKDGLADVKFRKLSRILVCGRVAQCREVFGDTLNESRDPDHG 161
                 |||..|.||||||||:..|:|...|.|||:::||.|||:.:..:||||:|||||||||.
Zfish   145 RSPSLDARKTGFITIGYRGSYTIGRDLQQDAKFRRVARITVCGKTSLAKEVFGETLNESRDPDR- 208

  Fly   162 GTDRYTSRFFLKHCYIEQAFDNLHDHGYRMAGSCGSGTAGSAA-EPKPGVDTEENRWNHYNEFVF 225
            ..:|||||::||:.::|||||.|.:.|:.|.....:||...|: :|     .|:..|..|.|:||
Zfish   209 PPERYTSRYYLKYNFLEQAFDRLAEVGFHMVACSSTGTCAYASNDP-----NEDKIWTSYTEYVF 268

  Fly   226 IRD 228
            .|:
Zfish   269 CRE 271

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ktl	NP_650926.1	BTB_POZ_KCTD8-like	1..99	CDD:349676	51/105 (49%)
		H1_KCTD12-like	106..227	CDD:409026	58/121 (48%)
kctd12.2	NP_001029191.1	BTB_POZ	13..112	CDD:453885	51/96 (53%)
		H1_KCTD12	153..271	CDD:409028	58/123 (47%)