Protein Alignment Ktl and KCTD5

DIOPT Version :10

• Sequence 1: NP_650926.1
• Gene: Ktl / 42475
• FlyBaseID: FBgn0038839
• Length: 228
• Species: Drosophila melanogaster
• Sequence 2: NP_061865.1
• Gene: KCTD5 / 54442
• HGNCID: 21423
• Length: 234
• Species: Homo sapiens
• Alignment Length: 220
• Identity: 53/220 - (24%)
• Similarity: 90/220 - (40%)
• Gaps: 63/220 - (28%)

  Fly     5 IELNVGGVSYTTTLATLLQDKSTLLAELFGEGRD-SLAKDSKGRYFLDRDGVLFRYILDFLRDKA 68
            :.|||||..:.||..||.:|..:.|..|.....| ...||..|.|.:|||...|..:|::||...
Human    46 VRLNVGGTYFLTTRQTLCRDPKSFLYRLCQADPDLDSDKDETGAYLIDRDPTYFGPVLNYLRHGK 110

  Fly    69 LHLPEGFRERQRLLREAEHFKLTAMLECIRS---ERDARPPGCITIGYRGSFQFGKDGLADVKFR 130
            |.:.:...| :.:|.|||.:.:|::::.::.   |||::                   .:.|..:
Human   111 LVINKDLAE-EGVLEEAEFYNITSLIKLVKDKIRERDSK-------------------TSQVPVK 155

  Fly   131 KLSRILVCGRVAQCRE--------------VFGDTLNESRDPDHGGTDRYTSRFFLKHCYIEQAF 181
            .:.|:|      ||:|              .|...::.....::|..|:..   ||  |.:.:
Human   156 HVYRVL------QCQEEELTQMVSTMSDGWKFEQLVSIGSSYNYGNEDQAE---FL--CVVSK-- 207

  Fly   182 DNLHDHGYRMAGSCGSGTAGSAAEP 206
             .||:..|           |:|:||
Human   208 -ELHNTPY-----------GTASEP 220

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ktl	NP_650926.1	BTB_POZ_KCTD8-like	1..99	CDD:349676	31/94 (33%)
		H1_KCTD12-like	106..227	CDD:409026	19/115 (17%)
KCTD5	NP_061865.1	BTB_POZ_KCTD5	40..151	CDD:349698	34/124 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	213..234		5/19 (26%)