Protein Alignment Ktl and Kctd8

DIOPT Version :10

• Sequence 1: NP_650926.1
• Gene: Ktl / 42475
• FlyBaseID: FBgn0038839
• Length: 228
• Species: Drosophila melanogaster
• Sequence 2: NP_001093642.1
• Gene: Kctd8 / 364148
• RGDID: 1312020
• Length: 476
• Species: Rattus norvegicus
• Alignment Length: 288
• Identity: 112/288 - (38%)
• Similarity: 154/288 - (53%)
• Gaps: 68/288 - (23%)

  Fly     2 PEIIELNVGGVSYTTTLATLLQDKSTLLAELFGEG--------RDSLAKDSKGRYFLDRDGVLFR 58
            ||::||||||..|.|..:|||....:.||.:|...        |..|.:||:.|:|:||||.|||
  Rat    43 PEVVELNVGGQVYVTKHSTLLSVPDSTLASMFSPSSPRGGARRRGDLPRDSRARFFIDRDGFLFR 107

  Fly    59 YILDFLRDKALHLPEGFRERQRLLREAEHFKLTAMLEC----IRSERDARPPGC----------- 108
            |:||:||||.|.|||.|.|::|||||||.|:||.:::.    :..:......||
  Rat   108 YVLDYLRDKQLALPEHFPEKERLLREAEFFQLTDLVKLLSPKVTKQNSLNDEGCQSDLEDNLSQG 172

  Fly   109 ---------------------------------------ITIGYRGSFQFGKDGLADVKFRKLSR 134
                                                   :|:|||||:...:|..||.|||:::|
  Rat   173 SSDALLLRGAAAGAPSSSGAHGVSGVVSGGSAPDKRSGFLTLGYRGSYTTVRDNQADAKFRRVAR 237

  Fly   135 ILVCGRVAQCREVFGDTLNESRDPDHGGTDRYTSRFFLKHCYIEQAFDNLHDHGYRMAGSCGSGT 199
            |:||||:|..:||||||||||||||. ..::|||||:||..|:|||||.|.:.|:.|.....|||
  Rat   238 IMVCGRIALAKEVFGDTLNESRDPDR-QPEKYTSRFYLKFTYLEQAFDRLSEAGFHMVACNSSGT 301

  Fly   200 AGSAAEPKPGVDTEENRWNHYNEFVFIR 227
            |....:.:     ::..|:.|.|::|.|
  Rat   302 AAFVNQYR-----DDKIWSSYTEYIFFR 324

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ktl	NP_650926.1	BTB_POZ_KCTD8-like	1..99	CDD:349676	52/108 (48%)
		H1_KCTD12-like	106..227	CDD:409026	59/170 (35%)
Kctd8	NP_001093642.1	BTB_POZ_KCTD8	41..150	CDD:349704	52/106 (49%)
		potassium channel tetramerization domain	46..145		50/98 (51%)
		H1_KCTD8	204..324	CDD:409029	57/125 (46%)