Protein Alignment Ktl and Kctd12

DIOPT Version :9

• Sequence 1: NP_001303467.1
• Gene: Ktl / 42475
• FlyBaseID: FBgn0038839
• Length: 228
• Species: Drosophila melanogaster
• Sequence 2: NP_808383.3
• Gene: Kctd12 / 239217
• MGIID: 2145823
• Length: 327
• Species: Mus musculus
• Alignment Length: 299
• Identity: 114/299 - (38%)
• Similarity: 154/299 - (51%)
• Gaps: 76/299 - (25%)

  Fly     2 PEIIELNVGGVSYTTTLATLLQDKSTLLAELFGEGR-DSLAKDSKGRYFLDRDGVLFRYILDFLR 65
            |:|:||||||..|.|...|::....:||..:|.:.: ..||:|||||:||||||.|||||||:||
Mouse    33 PDIVELNVGGQVYVTRRCTVVSVPDSLLWRMFTQQQPQELARDSKGRFFLDRDGFLFRYILDYLR 97

  Fly    66 DKALHLPEGFRERQRLLREAEHFKLTAMLECIRS------------------------------- 99
            |..|.||:.|.||.||.||||:|:|..::..:.:
Mouse    98 DLQLVLPDYFPERSRLQREAEYFELPELVRRLGAPQQPGPGPPPPHSRRGVHKEGSLGDELLPLG 162

  Fly   100 -------------------ERDARPP---------------------GCITIGYRGSFQFGKDGL 124
                               |..:|.|                     |.||||||||:..|:|..
Mouse   163 YAEPEPQEGASAGAPSPTLELASRSPSGGAAGPLLTPSQSLDGSRRSGYITIGYRGSYTIGRDAQ 227

  Fly   125 ADVKFRKLSRILVCGRVAQCREVFGDTLNESRDPDHGGTDRYTSRFFLKHCYIEQAFDNLHDHGY 189
            ||.|||:::||.|||:.:..:||||||||||||||. ..:|||||::||..::|||||.|.:.|:
Mouse   228 ADAKFRRVARITVCGKTSLAKEVFGDTLNESRDPDR-PPERYTSRYYLKFNFLEQAFDKLSESGF 291

  Fly   190 RMAGSCGSGTAGSAAEPKPGVDTEENRWNHYNEFVFIRD 228
            .|.....:||...|:...   .:|:..|..|.|:||.|:
Mouse   292 HMVACSSTGTCAFASSTD---QSEDKIWTSYTEYVFCRE 327

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ktl	NP_001303467.1	BTB	5..97	CDD:197585	49/92 (53%)
		BTB	5..91	CDD:295341	48/86 (56%)
Kctd12	NP_808383.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..28
		BTB	36..125	CDD:321966	49/88 (56%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	129..204		3/74 (4%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167848468
Domainoid	1	1.000	125	1.000	Domainoid score	I5438
eggNOG	1	0.900	-	-		E1_KOG2723
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	223	1.000	Inparanoid score	I3509
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG49144
OrthoDB	1	1.010	-	-		D1579292at2759
OrthoFinder	1	1.000	-	-		FOG0001212
OrthoInspector	1	1.000	-	-		otm43437
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR14499
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2965
SonicParanoid	1	1.000	-	-		X239
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	14	13.940