Protein Alignment Ktl and Kctd12b

DIOPT Version :9

• Sequence 1: NP_001303467.1
• Gene: Ktl / 42475
• FlyBaseID: FBgn0038839
• Length: 228
• Species: Drosophila melanogaster
• Sequence 2: NP_780638.1
• Gene: Kctd12b / 207474
• MGIID: 2444667
• Length: 292
• Species: Mus musculus
• Alignment Length: 279
• Identity: 111/279 - (39%)
• Similarity: 152/279 - (54%)
• Gaps: 58/279 - (20%)

  Fly     2 PEIIELNVGGVSYTTTLATLLQDKSTLLAELFG-EGRDSLAKDSKGRYFLDRDGVLFRYILDFLR 65
            ||||||||||..|.|...||:....:.|.|:|. :...||.:|:|||:|:||||.||||:||::|
Mouse    20 PEIIELNVGGQVYITRYPTLISIPGSRLWEMFSVKNPCSLIQDNKGRFFIDRDGFLFRYVLDYMR 84

  Fly    66 DKALHLPEGFRERQRLLREAEHFKLTAMLECIRSE--------RDARP----------------- 105
            |..:.||:.|.|..||.||||:|||..:.:.:..:        .|:.|
Mouse    85 DMQVVLPDHFPECGRLHREAEYFKLPELAKMLAPKMNKLNSIGNDSCPIDLEELSPSIDTTFNFS 149

  Fly   106 --------------------------PGCITIGYRGSFQFGKDGLADVKFRKLSRILVCGRVAQC 144
                                      .|.||||||||:..|:|..||.|||:::||:|||:::..
Mouse   150 STNSIHISGPDNPMVLRAAPGSELKKAGFITIGYRGSYTLGRDSQADAKFRRVARIMVCGKISLA 214

  Fly   145 REVFGDTLNESRDPDHGGTDRYTSRFFLKHCYIEQAFDNLHDHGYRMAGSCGSGTAGSAAEPKPG 209
            :||||||||||||||. ..:|||||::||..::|||||.|.|.|:.|.....:||.....:
Mouse   215 KEVFGDTLNESRDPDR-PPERYTSRYYLKFTFLEQAFDKLADAGFHMVACNSTGTCTVTHD---- 274

  Fly   210 VDTEENRWNHYNEFVFIRD 228
             .|::..|..|.|:||.|:
Mouse   275 -QTDDRIWTSYTEYVFYRE 292

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ktl	NP_001303467.1	BTB	5..97	CDD:197585	46/92 (50%)
		BTB	5..91	CDD:295341	45/86 (52%)
Kctd12b	NP_780638.1	BTB_POZ_KCTD8-like	19..118	CDD:349676	49/97 (51%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	125	1.000	Domainoid score	I5438
eggNOG	1	0.900	-	-		E1_KOG2723
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	223	1.000	Inparanoid score	I3509
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG49144
OrthoDB	1	1.010	-	-		D1579292at2759
OrthoFinder	1	1.000	-	-		FOG0001212
OrthoInspector	1	1.000	-	-		otm43437
orthoMCL	1	0.900	-	-		OOG6_106901
Panther	1	1.100	-	-	O	PTHR14499
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2965
SonicParanoid	1	1.000	-	-		X239
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.870