DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ktl and Kctd1

DIOPT Version :10

Sequence 1:NP_650926.1 Gene:Ktl / 42475 FlyBaseID:FBgn0038839 Length:228 Species:Drosophila melanogaster
Sequence 2:NP_001136203.1 Gene:Kctd1 / 106931 MGIID:1918269 Length:861 Species:Mus musculus


Alignment Length:238 Identity:73/238 - (30%)
Similarity:118/238 - (49%) Gaps:45/238 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly     5 IELNVGGVSYTTTLATLLQDKSTLLAELFGEGRDSLAKDS-KGRYFLDRDGVLFRYILDFLRDKA 68
            :.::|||..||::||||.:...:.:..|| :|.:.:..|| |..||:||||.:|||||:|||...
Mouse   636 VHIDVGGHMYTSSLATLTKYPESRIGRLF-DGTEPIVLDSLKQHYFIDRDGQMFRYILNFLRTSK 699

  Fly    69 LHLPEGFRERQRLLREAEHFKLTAM-LECIRSERD------ARPPGCITIGYRGSFQFGKDGLAD 126
            |.:|:.|::...|..||::|:|..| ||..|.::|      :||..|:.:  |.:...|:     
Mouse   700 LLIPDDFKDYTLLYEEAKYFQLQPMLLEMERWKQDRETGRFSRPCECLVV--RVAPDLGE----- 757

  Fly   127 VKFRKLSRILVCGRVAQCREVF---GDTLNESRDPDHGGTDRYTSRFFLK-HCYIE--QAFDNLH 185
                   ||.:.|..:...|||   ||.:..|.:........:..||.|. :|::.  |..:.|.
Mouse   758 -------RITLSGDKSLIEEVFPEIGDVMCNSVNAGWNHDSTHVIRFPLNGYCHLNSVQVLERLQ 815

  Fly   186 DHGYRMAGSCGSGTAGSAAEPKPGVDTEENRWNHYNEFVFIRD 228
            ..|:.:.||||.           |||:.:     ::|:|..|:
Mouse   816 QRGFEIVGSCGG-----------GVDSSQ-----FSEYVLRRE 842

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
KtlNP_650926.1 BTB_POZ_KCTD8-like 1..99 CDD:349676 40/95 (42%)
H1_KCTD12-like 106..227 CDD:409026 28/126 (22%)
Kctd1NP_001136203.1 DUF3504 279..435 CDD:463430
PHA03247 <489..635 CDD:223021
BTB_POZ_KCTD1 632..736 CDD:349695 42/100 (42%)
Blue background indicates that the domain is not in the aligned region.

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