DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ktl and kctd16

DIOPT Version :9

Sequence 1:	NP_001303467.1	Gene:	Ktl / 42475	FlyBaseID:	FBgn0038839	Length:	228	Species:	Drosophila melanogaster
Sequence 2:	XP_002935310.1	Gene:	kctd16 / 100497743	XenbaseID:	XB-GENE-6032729	Length:	428	Species:	Xenopus tropicalis

Alignment Length:	261	Identity:	113/261 - (43%)
Similarity:	155/261 - (59%)	Gaps:	41/261 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 PEIIELNVGGVSYTTTLATLLQDKSTLLAELFGEGRDS---LAKDSKGRYFLDRDGVLFRYILDF 63
            ||::||||||..|.|..|||.....:||.::|...|||   ||||:|||:|:||||.||||:||:
Frog    24 PEVVELNVGGQVYFTRHATLTSIPHSLLWKMFTCKRDSVNDLAKDAKGRFFIDRDGFLFRYVLDY 88

  Fly    64 LRDKALHLPEGFRERQRLLREAEHFKLTAMLECIRSERDARPP---------------------- 106
            |||:.:.||:.|.||.||.||||:|:|..:::.:..|...:.|
Frog    89 LRDRQVVLPDHFPERGRLKREAEYFQLPDLVKLLIPEEVKQSPDDYCHSDYEEVSQGSETRICPS 153

  Fly   107 ----------GCITIGYRGSFQFGKDGLADVKFRKLSRILVCGRVAQCREVFGDTLNESRDPDHG 161
                      |.:|:|||||...|::..||.|||::.|||||||::..:||||||||||||||.
Frog   154 ASLMPSDRKWGFVTVGYRGSCTMGRESQADAKFRRVPRILVCGRISLAKEVFGDTLNESRDPDR- 217

  Fly   162 GTDRYTSRFFLKHCYIEQAFDNLHDHGYRMAGSCGSGTAGSAAEPKPGVDTEENRWNHYNEFVFI 226
            ..::|||||:||..::|:|||.|.:.|:.|. :|.|....|.....    |::..|:.|.|:||.
Frog   218 APEKYTSRFYLKFKHLERAFDMLSESGFLMV-ACNSSVTASFVNQY----TDDKIWSSYTEYVFY 277

  Fly   227 R 227
            |
Frog   278 R 278

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ktl	NP_001303467.1	BTB	5..97	CDD:197585	51/94 (54%)
Ktl	NP_001303467.1	BTB	5..91	CDD:295341	50/88 (57%)
kctd16	XP_002935310.1	BTB_POZ_KCTD16	23..125	CDD:349706	53/100 (53%)
kctd16	XP_002935310.1	H1_KCTD16	160..280	CDD:409030	58/125 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	124	1.000	Domainoid score	I5438
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	227	1.000	Inparanoid score	I3393
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1579292at2759
OrthoFinder	1	1.000	-	-		FOG0001212
OrthoInspector	1	1.000	-	-		otm48582
Panther	1	1.100	-	-	O	PTHR14499
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X239
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	10.070