DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ktl and kctd1

DIOPT Version :9

Sequence 1:	NP_001303467.1	Gene:	Ktl / 42475	FlyBaseID:	FBgn0038839	Length:	228	Species:	Drosophila melanogaster
Sequence 2:	XP_012820753.2	Gene:	kctd1 / 100486970	XenbaseID:	XB-GENE-6076050	Length:	840	Species:	Xenopus tropicalis

Alignment Length:	238	Identity:	72/238 - (30%)
Similarity:	117/238 - (49%)	Gaps:	45/238 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 IELNVGGVSYTTTLATLLQDKSTLLAELFGEGRDSLAKDS-KGRYFLDRDGVLFRYILDFLRDKA 68
            :.::|||..||::||||.:...:.:..|| :|.:.:..|| |..||:||||.:|||||:|||...
Frog   615 VHIDVGGHMYTSSLATLTKYPDSRIGRLF-DGTEPIVLDSLKQHYFIDRDGQMFRYILNFLRTSK 678

  Fly    69 LHLPEGFRERQRLLREAEHFKLTAM-LECIRSERD------ARPPGCITIGYRGSFQFGKDGLAD 126
            |.:.:.|::...|..||::|:|..| ||..|.::|      :||..|:.:  |.:...|:
Frog   679 LLISDDFKDYSLLYEEAKYFQLQPMLLELERWKQDKEAGRFSRPCECLVV--RVAPDLGE----- 736

  Fly   127 VKFRKLSRILVCGRVAQCREVF---GDTLNESRDPDHGGTDRYTSRFFLK-HCYIE--QAFDNLH 185
                   ||.:.|..:...|||   ||.:..|.:........:..||.|. :|::.  |..:.|.
Frog   737 -------RITLSGDKSLIEEVFPEIGDVMCNSVNAGWNHDSTHVIRFPLNGYCHLNSVQVLERLQ 794

  Fly   186 DHGYRMAGSCGSGTAGSAAEPKPGVDTEENRWNHYNEFVFIRD 228
            ..|:.:.||||.           |||:.:     ::|:|..|:
Frog   795 HRGFEIVGSCGG-----------GVDSSQ-----FSEYVLRRE 821

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ktl	NP_001303467.1	BTB	5..97	CDD:197585	39/93 (42%)
Ktl	NP_001303467.1	BTB	5..91	CDD:295341	35/86 (41%)
kctd1	XP_012820753.2	DNA_BRE_C	270..435	CDD:412227
kctd1	XP_012820753.2	BTB_POZ_KCTD1	611..715	CDD:349695	41/100 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910