DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment KaiR1D and GLR2.9

DIOPT Version :9

Sequence 1:	NP_650925.1	Gene:	KaiR1D / 42473	FlyBaseID:	FBgn0038837	Length:	853	Species:	Drosophila melanogaster
Sequence 2:	NP_001325277.1	Gene:	GLR2.9 / 817458	AraportID:	AT2G29100	Length:	942	Species:	Arabidopsis thaliana

Alignment Length:	895	Identity:	193/895 - (21%)
Similarity:	356/895 - (39%)	Gaps:	145/895 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 LILNCRKAQSLPDIIKIGGLFHPADDHQEL---AFRQAVDRINADR-SILPRSKLVAQIERISPF 76
            |::.....|:....||:|.:........::   :.:.||....||. :.|.|..|..   |.|..
plant    18 LLMGVGLGQNQTSEIKVGVVLDLNTTFSKICLTSIKMAVSDFYADHPNYLTRLTLHV---RDSME 79

  Fly    77 DSFHAGKRVCGLLNI-GVAAIFGPQSSHTASHVQSICDNMEIPHLENRWDYRLRRESCLVNLYPH 140
            |:..|......|:.. .|:||.||.:|..|..:..:.:..::|.:      .....|.|:.....
plant    80 DTVQASAAALDLIKTEQVSAIIGPINSMQADFMIKLANKTQVPTI------TFSATSPLLTSIKS 138

  Fly   141 P---------NTLSKAYVDIVRHWGWKTFTIIYENNDGIVRLQELLKAHGMTPF------PITVR 190
            |         ::..:|...|.:.:.|:....||.:|:         ...|..||      .:.|:
plant   139 PYFVRATIDDSSQVRAIASIFKFFRWRRVVAIYVDNE---------FGEGFMPFLFDALQDVEVK 194

  Fly   191 ------QLSDSGDYRPLLKQIKNSAEAHIV-LDCSTE-RIHEVLKQAQQIGMMSDYHSYLVTSLD 247
                  :..|....:.|.|.::..|...:| ::.|.. |:.::   |:.||||.:.:.:|:|:..
plant   195 RSVIPPEAIDDEIQKELRKLMERQARVFVVHMESSLALRVFQI---ARDIGMMEEGYVWLMTNGM 256

  Fly   248 LHTV-NLDEFRYGGT--NITGFR--LINEKIVSDVVRQWSIDEKGLLRSANLTTVRSETALMYDA 307
            .|.: :::..|...|  .:.|.|  :...|.:.|...:|.            .|...|...|.|.
plant   257 THMMRHINNGRSLNTIEGVLGVRSHVPKSKELGDFRLRWK------------RTFEKENPSMRDD 309

  Fly   308 VHLFAKALHDLDTS-----QQIDIHPISCDGQSTWQ-------------HGFSLINYMKIVEMKG 354
            :::||...:|..|:     ::.:...:..|..||..             :|.||......|...|
plant   310 LNVFALWAYDSITALAKAVEKANTKSLWYDNGSTLSKNRTDLGNVGVSLYGPSLQKAFSEVRFNG 374

  Fly   355 LTNVIK-FDHQGFRTDFMLDIVELTPAGIRKIGTWNSTLPDGINFTRTFSQKQQEIEANLKNKTL 418
            |....| .|.|.....|  :|:.......|.||.|  |..||: ...|.|.|:.........|:.
plant   375 LAGEFKLIDGQLQSPKF--EIINFVGNEERIIGFW--TPRDGL-MDATSSNKKTLGPVIWPGKSK 434

  Fly   419 VVTTILSNP--------------YCMRKESAIPLSGNDQFEGYAVDLIHEISKSLGFNYKIQLVP 469
            :|......|              :...|.:..|::......|||:::.....|.|.:    .::|
plant   435 IVPKGWEIPGKKLRVGVPMKKGFFDFVKVTINPITNKKTPTGYAIEIFEAALKELPY----LVIP 495

  Fly   470 D-GSYGSLNKLTGEWNGMIRELLEQRADLAIADLTITFEREQAVDFTTPFMNLGVSILYRKPIKQ 533
            : .|:.|.|    .:|.::.::.::..|..:.|:|||..|....|||.||...|||::.  |::.
plant   496 EYVSFESPN----NYNNLVYQVYDKTWDAVVGDITITANRSLYADFTLPFTESGVSMMV--PVRD 554

  Fly   534 PPN--LFSFLSPLSLDVWIYMATAYLGVSVLLFILAKFTPYEWPAYTDAHGEKVESQFTLLNCMW 596
            ..|  .:.||.|.||::|:.....::.:..::::      :|....||..|   ..|:.:...:|
plant   555 NENKDTWVFLEPWSLELWVTTGCFFVFIGFVVWL------FEHRVNTDFRG---PPQYQIGTSLW 610

  Fly   597 FAIGSLMQQGCDFLPKALSTRMVAGIWWFFTLIMISSYTANLAAFLTVERMDSPIESAEDLAK-Q 660
            |:..:::....:.:...|: |.|..:|.|..|::..||||:|.:||||:.:...:.:..||.| :
plant   611 FSFSTMVFAHRENVVSNLA-RFVVVVWCFVVLVLTQSYTASLTSFLTVQSLQPTVTNVNDLIKNR 674

  Fly   661 TRIKYGALKGGSTAAFFRDSKISTYQRMWSFMESARPSVFTASNGEGVERVAKGKGSYAFLMEST 725
            ..:.|   :||   ||.:|..:..     .|.|.......:|.:.:.:....|.||..|...|..
plant   675 DCVGY---QGG---AFVKDILLGL-----GFHEDQLKPFDSAKDADDLLSKGKSKGIAAAFDEVA 728

  Fly   726 SIEYVTERNC-ELTQVGGMLDTKSYGIATPPNSPYRTAINSVILKLQEEGKLHILKTKWWKEKRG 789
            .::.:..::| :...|.....|..:|.|.|.|||.....:..||.|.:......::.:|:.:|
plant   729 YLKAILSQSCSKYVMVEPTFKTGGFGFAFPKNSPLTGEFSRAILNLTQNNVTQQIEDRWFPKK-- 791

  Fly   790 GGKCRVETSKSSSAANELGLANVGGVFVVLMGGMGVACVIAVCEFVWKSR 839
             ..|....:..||  |.|.|::..|:|::....:..:.::.|..|:::.|
plant   792 -NDCPDPMTALSS--NRLNLSSFLGLFLIAGTAISFSLLVFVALFLYEHR 838

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
KaiR1D	NP_650925.1	PBP1_iGluR_Kainate	31..397	CDD:107377	86/417 (21%)
		ANF_receptor	42..378	CDD:279440	77/387 (20%)
		Periplasmic_Binding_Protein_Type_2	415..785	CDD:304360	89/388 (23%)
		Lig_chan	547..823	CDD:278489	62/277 (22%)
GLR2.9	NP_001325277.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	82	0.746	Domainoid score	I2907
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG60082
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000021
OrthoInspector	1	1.000	-	-		mtm1027
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18966
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	9	8.880